N
Nora D. Volkow
Researcher at National Institute on Drug Abuse
Publications - 1038
Citations - 121498
Nora D. Volkow is an academic researcher from National Institute on Drug Abuse. The author has contributed to research in topics: Dopamine & Addiction. The author has an hindex of 165, co-authored 958 publications receiving 107463 citations. Previous affiliations of Nora D. Volkow include National Institutes of Health & North Shore University Hospital.
Papers
More filters
Journal ArticleDOI
Neurobiology of addiction: A neurocircuitry analysis.
George F. Koob,Nora D. Volkow +1 more
TL;DR: Molecular genetic studies have identified transduction and transcription factors that act in neurocircuitry associated with the development and maintenance of addiction that might mediate initial vulnerability, maintenance, and relapse associated with addiction.
Journal ArticleDOI
Brain dopamine and obesity.
Gene-Jack Wang,Gene-Jack Wang,Nora D. Volkow,Nora D. Volkow,Jean Logan,Naoml R Pappas,Christopher Wong,Wel Zhu,Noelwah Netusll,Joanna S. Fowler +9 more
TL;DR: Dopamine modulates motivation and reward circuits and hence dopamine deficiency in obese individuals may perpetuate pathological eating as a means to compensate for decreased activation of these circuits.
Journal ArticleDOI
Distribution Volume Ratios without Blood Sampling from Graphical Analysis of PET Data
Jean Logan,Joanna S. Fowler,Nora D. Volkow,Nora D. Volkow,Gene-Jack Wang,Yu-Shin Ding,David Alexoff +6 more
TL;DR: In this paper, the authors proposed a graphical method for determining the distribution volume ratio (DVR), which is a linear function of receptor availability, which does not require blood sampling and is widely used as a model parameter in imaging studies.
Journal ArticleDOI
Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects
Jean Logan,Joanna S. Fowler,Nora D. Volkow,Alfred P. Wolf,Stephen L. Dewey,David J. Schlyer,Robert R. MacGregor,Robert Hitzemann,Bernard Bendriem,S. John Gatley,David R. Christman +10 more
TL;DR: It can be shown that, for many systems, linearity is effectively reached some time before this, and this method provides an easy, rapid method for comparison of the reproducibility of repeated measures in a single subject, for longitudinal or drug intervention protocols, or for comparing experimental results between subjects.
Journal ArticleDOI
Addiction, a Disease of Compulsion and Drive: Involvement of the Orbitofrontal Cortex
Nora D. Volkow,Joanna S. Fowler +1 more
TL;DR: It is implied that pleasure per se is not enough to maintain compulsive drug administration in the drugaddicted subject and that drugs that could interfere with the activation of the striato-thalamo-orbitofrontal circuit could be beneficial in the treatment of drug addiction.