O
Olga Addimanda
Researcher at University of Bologna
Publications - 64
Citations - 1458
Olga Addimanda is an academic researcher from University of Bologna. The author has contributed to research in topics: Synovitis & Psoriatic arthritis. The author has an hindex of 19, co-authored 58 publications receiving 1152 citations. Previous affiliations of Olga Addimanda include Santa Maria Nuova Hospital & University of Modena and Reggio Emilia.
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Journal ArticleDOI
Efficacy of anti-TNF alpha in severe and/or refractory Behçet's disease: Multicenter study of 124 patients
H. Vallet,Sophie Rivière,Alice Sanna,Alban Deroux,Guillaume Moulis,Olga Addimanda,Carlo Salvarani,Marc Lambert,Philip Bielefeld,Pascal Sève,Jean Sibilia,Jl Pasquali,J.B. Fraison,Isabelle Marie,Laurent Perard,L. Bouillet,F. Cohen,Damien Sène,Yoland Schoindre,O Lidove,P. Le Hoang,Eric Hachulla,Olivier Fain,Xavier Mariette,Thomas Papo,Bertrand Wechsler,Bahram Bodaghi,M. Resche Rigon,Patrice Cacoub,D. Saadoun +29 more
TL;DR: Anti-TNF alpha therapy is efficient in all severe and refractory BD manifestations and appears to be similar regardless of the anti-T NF agent used (infliximab or adalimumab).
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A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility.
F. David Carmona,Sarah L. Mackie,Jose Ezequiel Martin,John C. Taylor,Augusto Vaglio,Stephen Eyre,Lara Bossini-Castillo,Santos Castañeda,Maria C. Cid,José Hernández-Rodríguez,Sergio Prieto-González,Roser Solans,Marc Ramentol-Sintas,M. Francisca González-Escribano,Lourdes Ortiz-Fernández,Inmaculada C. Morado,Javier Narváez,José A. Miranda-Filloy,Lorenzo Beretta,Claudio Lunardi,Marco A. Cimmino,Davide Gianfreda,Daniele Santilli,Giuseppe A. Ramirez,Alessandra Soriano,Francesco Muratore,Giulia Pazzola,Olga Addimanda,Cisca Wijmenga,Torsten Witte,Jan H. Schirmer,Frank Moosig,Verena Schönau,Andre Franke,Øyvind Palm,Øyvind Molberg,Andreas P. Diamantopoulos,Simon Carette,David Cuthbertson,Lindsy J. Forbess,Gary S. Hoffman,Nader Khalidi,Curry L. Koening,Carol A. Langford,Carol A. McAlear,Larry W. Moreland,Paul A. Monach,Christian Pagnoux,Philip Seo,Robert Spiera,Antoine G. Sreih,Kenneth J. Warrington,Steven R. Ytterberg,Peter K. Gregersen,Colin T. Pease,Andrew Gough,Michael J. Green,Lesley Hordon,Stephen Jarrett,Richard A. Watts,Sarah Levy,Yusuf Patel,Sanjeet Kamath,Bhaskar Dasgupta,Jane Worthington,Bobby P. C. Koeleman,Paul I.W. de Bakker,Jennifer H. Barrett,Carlo Salvarani,Peter A. Merkel,Miguel A. González-Gay,Ann W. Morgan,Javier Martín +72 more
TL;DR: This study provides evidence of a strong contribution of HLA class I and II molecules to susceptibility to GCA, and confirmed a key role for the functional PTPN22 rs2476601 variant and proposed other putative risk loci involved in Th1, Th17, and Treg cell function.
Journal ArticleDOI
WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis.
G. Nalesso,B.L. Thomas,J. Sherwood,J. Sherwood,Jing Yu,Olga Addimanda,S.E. Eldridge,Anne Sophie Thorup,Leslie Dale,Georg Schett,Jochen Zwerina,N.M. Eltawil,N.M. Eltawil,Costantino Pitzalis,Francesco Dell'Accio +14 more
TL;DR: In osteoarthritis, WNT16 maintains a balanced canonical WNT signalling and prevents detrimental excessive activation, thereby supporting the homeostasis of progenitor cells.
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New findings in osteoarthritis pathogenesis: therapeutic implications:
TL;DR: This review focuses on the new perspectives which can provide insight into the crucial pathways that drive cartilage-bone physiopathology and discusses the critical signaling and effector molecules that can activate cellular and molecular processes in both cartilage and bone cells.
Journal ArticleDOI
Tocilizumab for severe refractory neuro-Behçet: Three cases IL-6 blockade in neuro-Behçet
TL;DR: The data suggest that TCZ may be considered for patients with refractory NBD, and the prednisone dose could successfully be tapered to about 20mg/day, while in another patient glucocorticoids could safely be withdrawn.