Showing papers by "Owen White published in 2014"
King Abdulaziz University1, University of Queensland2, University of California, Davis3, Joint Genome Institute4, DSM5, Max Planck Society6, ATCC7, Los Alamos National Laboratory8, Seoul National University9, Johns Hopkins University10, Ghent University11, Université catholique de Louvain12, Massachusetts Institute of Technology13, University of Wisconsin-Madison14, Chinese Academy of Sciences15, Institut national de la recherche agronomique16, University of Maryland, Baltimore17, Baylor College of Medicine18, Argonne National Laboratory19, Oak Ridge National Laboratory20, Jacobs University Bremen21, Lawrence Berkeley National Laboratory22, Howard Hughes Medical Institute23, National Center for Agricultural Utilization Research24, Saint Petersburg Academic University25, Korea Research Institute of Bioscience and Biotechnology26, Chinese Ministry of Education27, University of Gothenburg28, J. Craig Venter Institute29, University of Toronto30, University of Colorado Boulder31, Wellcome Trust Sanger Institute32, Zhejiang University33, Spanish National Research Council34, CABI35, Woods Hole Oceanographic Institution36, King Abdullah University of Science and Technology37, Michigan State University38, University of Vienna39, French Alternative Energies and Atomic Energy Commission40, University of Copenhagen41, Natural Environment Research Council42, University of Georgia43
TL;DR: This article proposed a systematic effort to produce a comprehensive genomic catalog of all cultured Bacteria and Archaea by sequencing, where available, the type strain of each species with a validly published name.
Abstract: Microbes hold the key to life. They hold the secrets to our past (as the descendants of the earliest forms of life) and the prospects for our future (as we mine their genes for solutions to some of the planet's most pressing problems, from global warming to antibiotic resistance). However, the piecemeal approach that has defined efforts to study microbial genetic diversity for over 20 years and in over 30,000 genome projects risks squandering that promise. These efforts have covered less than 20% of the diversity of the cultured archaeal and bacterial species, which represent just 15% of the overall known prokaryotic diversity. Here we call for the funding of a systematic effort to produce a comprehensive genomic catalog of all cultured Bacteria and Archaea by sequencing, where available, the type strain of each species with a validly published name (currently∼11,000). This effort will provide an unprecedented level of coverage of our planet's genetic diversity, allow for the large-scale discovery of novel genes and functions, and lead to an improved understanding of microbial evolution and function in the environment.
169 citations
King Abdulaziz University1, University of Queensland2, University of California, Davis3, Joint Genome Institute4, DSM5, Max Planck Society6, ATCC7, Los Alamos National Laboratory8, Seoul National University9, Johns Hopkins University10, Ghent University11, Université catholique de Louvain12, Massachusetts Institute of Technology13, University of Wisconsin-Madison14, Chinese Academy of Sciences15, Institut national de la recherche agronomique16, University of Maryland, Baltimore17, Baylor College of Medicine18, Argonne National Laboratory19, Oak Ridge National Laboratory20, Jacobs University Bremen21, Lawrence Berkeley National Laboratory22, Howard Hughes Medical Institute23, National Center for Agricultural Utilization Research24, Saint Petersburg Academic University25, Korea Research Institute of Bioscience and Biotechnology26, Chinese Ministry of Education27, University of Gothenburg28, J. Craig Venter Institute29, University of Toronto30, University of Colorado Boulder31, Wellcome Trust Sanger Institute32, Zhejiang University33, Spanish National Research Council34, CABI35, Woods Hole Oceanographic Institution36, King Abdullah University of Science and Technology37, Michigan State University38, University of Vienna39, French Alternative Energies and Atomic Energy Commission40, University of Copenhagen41, Natural Environment Research Council42, University of Georgia43
TL;DR: This paper proposed a systematic effort to produce a comprehensive genomic catalog of all cultured Bacteria and Archaea by sequencing, where available, the type strain of each species with a validly published name.
Abstract: Microbes hold the key to life. They hold the secrets to our past (as the descendants of the earliest forms of life) and the prospects for our future (as we mine their genes for solutions to some of the planet's most pressing problems, from global warming to antibiotic resistance). However, the piecemeal approach that has defined efforts to study microbial genetic diversity for over 20 years and in over 30,000 genome projects risks squandering that promise. These efforts have covered less than 20% of the diversity of the cultured archaeal and bacterial species, which represent just 15% of the overall known prokaryotic diversity. Here we call for the funding of a systematic effort to produce a comprehensive genomic catalog of all cultured Bacteria and Archaea by sequencing, where available, the type strain of each species with a validly published name (currently∼11,000). This effort will provide an unprecedented level of coverage of our planet's genetic diversity, allow for the large-scale discovery of novel genes and functions, and lead to an improved understanding of microbial evolution and function in the environment.