P
Pascal De Tullio
Researcher at University of Liège
Publications - 128
Citations - 2442
Pascal De Tullio is an academic researcher from University of Liège. The author has contributed to research in topics: Benzothiadiazine & AMPA receptor. The author has an hindex of 26, co-authored 122 publications receiving 2106 citations. Previous affiliations of Pascal De Tullio include Université libre de Bruxelles.
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Journal ArticleDOI
Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice.
Vincent Lambert,Julie Lecomte,Sylvain Hansen,Silvia Blacher,Maria-Luz Alvarez Gonzalez,Ingrid Struman,Nor Eddine Sounni,Eric Rozet,Pascal De Tullio,Jean-Michel Foidart,Jean-Marie Rakic,Agnès Noël +11 more
TL;DR: This standardized protocol can be applied to transgenic mice and can include treatments with drugs, recombinant proteins, antibodies, adenoviruses and pre-microRNAs to aid in the search for new molecular regulators and the identification of novel targets for innovative treatments.
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Blocking Lipid Synthesis Overcomes Tumor Regrowth and Metastasis after Antiangiogenic Therapy Withdrawal
Nor Eddine Sounni,Jonathan Cimino,Silvia Blacher,Irina Primac,Alice Truong,Gabriel Mazzucchelli,Alexandra Paye,David Calligaris,Delphine Debois,Pascal De Tullio,Bernard Mari,Edwin De Pauw,Agnès Noël +12 more
TL;DR: Evidence for tumor adaptation to vascular endothelial growth factor blockade through a metabolic shift toward carbohydrate and lipid metabolism in tumors is provided and key molecules involved in lipid metabolism as putative therapeutic targets are identified.
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Effect of head-to-head addition in vinyl acetate controlled radical polymerization: why is Co(acac)2-mediated polymerization so much better?
Aurélie N. Morin,Christophe Detrembleur,Christine Jérôme,Pascal De Tullio,Rinaldo Poli,Antoine Debuigne +5 more
TL;DR: In this paper, a detailed investigation by 1H, 13C and multiplicity-edited HSQC and DEPT-135 NMR of the PVAc obtained by organometallic mediated radical polymerization (OMRP) is presented.
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3-(Alkylamino)-4h-Pyrido[4,3-E]-1,2,4-Thiadiazine 1,1-Dioxides as Powerful Inhibitors of Insulin Release from Rat Pancreatic B-Cells: A New Class of Potassium Channel Openers?
Bernard Pirotte,Pascal De Tullio,Philippe Lebrun,M. H. Antoine,Jeanine Fontaine,Bernard Masereel,Marc Schynts,Léon Dupont,André Herchuelz,Jacques Delarge +9 more
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Design, Synthesis, and Pharmacology of Novel 7-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of AMPA Receptors†
Pierre Francotte,Pascal De Tullio,Eric Goffin,Gaëlle Dintilhac,E. Graindorge,Pierre Fraikin,Pierre Lestage,Laurence Danober,Jean-Yves Thomas,Daniel-Henri Caignard,Bernard Pirotte +10 more
TL;DR: The most potent compound, 4-ethyl-7-fluoro-3,4-dihydro-2H-1,2,4 -benzothiadiazine 1,1-dioxide was found to be active in an object recognition test in rats demonstrating cognition enhancing effects in vivo after oral administration.