P
Paul Sopp
Researcher at University of Oxford
Publications - 77
Citations - 4116
Paul Sopp is an academic researcher from University of Oxford. The author has contributed to research in topics: Antigen & CD8. The author has an hindex of 35, co-authored 73 publications receiving 3381 citations. Previous affiliations of Paul Sopp include Newbury College & University of Giessen.
Papers
More filters
Journal ArticleDOI
Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.
Yanchun Peng,Alexander J. Mentzer,G Liu,G Liu,X Yao,Z Yin,D Dong,D Dong,Wanwisa Dejnirattisai,T Rostron,P Supasa,C Liu,Cesar Lopez-Camacho,J Slon-Campos,Yuguang Zhao,David I. Stuart,Guido C. Paesen,Jonathan M. Grimes,Alfred A. Antson,Oliver W. Bayfield,Hawkins Dedp.,Ker D-S.,B Wang,Lance Turtle,Krishanthi Subramaniam,Paul Thomson,P Zhang,Christina Dold,Jeremy Ratcliff,Peter Simmonds,T I de Silva,Paul Sopp,Dannielle Wellington,U S Rajapaksa,Chen Y-L.,Mariolina Salio,Giorgio Napolitani,Wayne Paes,Persephone Borrow,Benedikt M. Kessler,J W Fry,N F Schwabe,Malcolm G Semple,Malcolm G Semple,J K Baillie,Shona C Moore,Openshaw Pjm.,M A Ansari,Susanna Dunachie,Eleanor Barnes,John Frater,G Kerr,Philip J. R. Goulder,T Lockett,R Levin,Y Zhang,Y Zhang,R Jing,Ho L-P.,Richard J. Cornall,Christopher P. Conlon,Paul Klenerman,Gavin R. Screaton,Juthathip Mongkolsapaya,Andrew J. McMichael,Julian C. Knight,Graham S. Ogg,Tao Dong +67 more
TL;DR: The identification of T cell responses associated with milder disease will support an understanding of protective immunity and highlights the potential of including non-spike proteins within future COVID-19 vaccine design.
Journal ArticleDOI
Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia
Alice Giustacchini,Supat Thongjuea,Nikolaos Barkas,Petter S. Woll,Benjamin J. Povinelli,Christopher A.G. Booth,Paul Sopp,Ruggiero Norfo,Alba Rodriguez-Meira,Neil Ashley,Lauren Jamieson,Paresh Vyas,Kristina Anderson,Åsa Segerstolpe,Hong Qian,Ulla Olsson-Strömberg,Satu Mustjoki,Rickard Sandberg,Rickard Sandberg,Sten Eirik W. Jacobsen,Adam J. Mead,Adam J. Mead +21 more
TL;DR: A method that combines high-sensitivity mutation detection with whole-transcriptome analysis of the same single cell is developed, illustrating how single-cell analysis can identify subpopulations of therapy-resistant SCs that are not apparent through cell-population analysis.
Journal Article
Identification of two distinct populations of dendritic cells in afferent lymph that vary in their ability to stimulate T cells.
TL;DR: Considering the central role of dendritic cells in the initiation of immune responses in naive animals, the two cell types may have different roles in the induction of primary responses induced following infection or immunization.
Journal ArticleDOI
Role of T-Lymphocyte Subsets in Recovery from Respiratory Syncytial Virus Infection in Calves
TL;DR: CD8+ T cells play a dominant role in the recovery of calves from RSV infection, and virus was isolated in high titers from lungwashings of these animals 10 days after infection, whereas virus had been cleared from lung washings of all other animals.
Journal ArticleDOI
Protective epitopes on the fusion protein of respiratory syncytial virus recognized by murine and bovine monoclonal antibodies.
TL;DR: A comparison of the biological properties of MAbs to the F protein indicated that protection against RSV infection correlated with fusion inhibition rather than neutralization titre or complement-dependent lysis of virus-infected cells.