Oliver W. Bayfield

TL;DR: The identification of T cell responses associated with milder disease will support an understanding of protective immunity and highlights the potential of including non-spike proteins within future COVID-19 vaccine design.

TL;DR: The identification of T cell specificity and functionality associated with milder disease, highlights the potential importance of including non-spike proteins within future COVID-19 vaccine design.

TL;DR: It is shown that the ligand sphere of the polarization transfer catalyst itself becomes hyperpolarized and hence that the high-sensitivity detection of a number of reaction intermediates is possible and hydride ligand signals are shown to become visible through para-hydrogen-induced polarization rather than SABRE.

TL;DR: In this article, it was shown that phosphorylated SARS-CoV-2-N protein (pN) dimers, reconstituted via bacterial co-expression with protein kinase A, directly associate, in a phosphorylation-dependent manner, with the dimeric 14-3-3 protein, but not with its monomeric mutant.

TL;DR: Cryo-EM reconstructions indicate that capsid expansion affects the conformation of the portal protein, while still allowing DNA to be packaged, and suggest a mechanism by which structural events inside the capsid can be communicated to the outside.