P
Per-Ulf Tunn
Researcher at Charité
Publications - 90
Citations - 2764
Per-Ulf Tunn is an academic researcher from Charité. The author has contributed to research in topics: Soft tissue sarcoma & Sarcoma. The author has an hindex of 25, co-authored 85 publications receiving 2230 citations.
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Journal ArticleDOI
Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial
Stefan S. Bielack,Sigbjørn Smeland,Jeremy Whelan,Neyssa Marina,Gordana Jovic,Jane Hook,Mark Krailo,Mark C. Gebhardt,Zsuzsanna Papai,James O. Meyer,Helen Nadel,R. Lor Randall,Claudia Deffenbaugh,Rajaram Nagarajan,Bernadette Brennan,G. Douglas Letson,Lisa A. Teot,Allen M. Goorin,Daniel Baumhoer,Leo Kager,Mathias Werner,Ching C. Lau,Kirsten Sundby Hall,Hans Gelderblom,Paul A. Meyers,Richard Gorlick,Reinhard Windhager,Knut Helmke,Mikael Eriksson,Peter M. Hoogerbrugge,Paula J. Schomberg,Per-Ulf Tunn,Thomas Kühne,Heribert Jürgens,Henk van den Berg,Tom Böhling,Susan Picton,Marleen Renard,Peter Reichardt,Joachim Gerss,Trude Butterfass-Bahloul,Carol D. Morris,Pancras C.W. Hogendoorn,Beatrice Seddon,Gabriele Calaminus,Maria Michelagnoli,Catharina Dhooge,Matthew R. Sydes,Mark L. Bernstein +48 more
TL;DR: Investigation of maintenance therapy with pegylated interferon alfa-2b in patients whose osteosarcoma showed good histologic response (good response) to induction chemotherapy found that MAP plus IFN-α-2B was not statistically different from MAP alone.
Journal ArticleDOI
Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency
Michal Kovac,Claudia Blattmann,Sebastian Ribi,Jan Smida,Nikola S. Mueller,Florian Engert,Francesc Castro-Giner,Joachim Weischenfeldt,Monika Kovacova,Andreas H. Krieg,Dimosthenis Andreou,Per-Ulf Tunn,Hans Roland Dürr,Hans Rechl,Klaus-Dieter Schaser,Ingo Melcher,Stefan Burdach,Andreas E. Kulozik,Katja Specht,Karl Heinimann,Simone Fulda,Simone Fulda,Stefan S. Bielack,Gernot Jundt,Ian Tomlinson,Jan O. Korbel,Michaela Nathrath,Daniel Baumhoer +27 more
TL;DR: It is implied that multiple oncogenic pathways drive chromosomal instability during osteosarcoma evolution and result in the acquisition of BRCA-like traits, which could be therapeutically exploited.
Journal ArticleDOI
Best practices for the Management of Local-regional Recurrent Chordoma. A Position Paper by the Chordoma Global Consensus Group
Silvia Stacchiotti,Alessandro Gronchi,Piero Fossati,Toru Akiyama,Claire Alapetite,Michael Baumann,J.-Y. Blay,Stéphanie Bolle,Stefano Boriani,P. Bruzzi,R. Capanna,Augusto Caraceni,Riccardo Casadei,Vittoria Colia,Jürgen Debus,Thomas F. DeLaney,Anant Desai,Palma Dileo,S. Dijkstra,Francesco Doglietto,Adrienne M. Flanagan,Adrienne M. Flanagan,S. Froelich,P. A. Gardner,Hans Gelderblom,Ziya L. Gokaslan,Rick L. Haas,C. Heery,Nadia Hindi,Peter Hohenberger,Francis J. Hornicek,R. Imai,Lee Jeys,Robin L. Jones,Bernd Kasper,Akira Kawai,Marco Krengli,Andreas Leithner,I. Logowska,J. Martin Broto,Diego Mazzatenta,Carlo Morosi,Piero Nicolai,O. J. Norum,Sandip Pravin Patel,Nicolas Penel,P. Picci,S. Pilotti,Stefano Radaelli,F. Ricchini,Piotr Rutkowski,Susanne Scheipl,C. Sen,Elena Tamborini,Katherine Anne Thornton,Beate Timmermann,Valter Torri,Per-Ulf Tunn,M. Uhl,Y. Yamada,Damien C. Weber,Daniel Vanel,Peter Pal Varga,C. L. A. Vleggeert-Lankamp,Paolo G. Casali,Josh Sommer +65 more
TL;DR: The consensus achieved during a second consensus group meeting in November 2015 to address the treatment of locally relapsed chordoma complements the recommendations of the first position paper and is the subject of the present publication.
Journal ArticleDOI
Diffusion-weighted magnetic resonance imaging allows monitoring of anticancer treatment effects in patients with soft-tissue sarcomas.
Oliver Dudeck,M Zeile,Daniel Pink,Maciej Pech,Per-Ulf Tunn,Peter Reichardt,Wolf-Dieter Ludwig,Bernd Hamm +7 more
TL;DR: To determine if diffusion‐weighted imaging (DWI) can be used as a surrogate marker of tumor response to anticancer therapy in patients with soft‐tissue sarcomas, diffusion‐ weighted imaging is used.
Journal ArticleDOI
Noninvasive magnetic resonance thermography of soft tissue sarcomas during regional hyperthermia: correlation with response and direct thermometry.
Johanna Gellermann,Bert Hildebrandt,Rolf D. Issels,Hildegard Ganter,Waldemar Wlodarczyk,Volker Budach,Roland Felix,Per-Ulf Tunn,Peter Reichardt,Peter Wust +9 more
TL;DR: Noninvasive magnetic resonance thermography for the monitoring of regional hyperthermia (RHT) in patients with soft tissue sarcomas of the lower extremities and pelvis is evaluated.