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Carsten O. Daub

Researcher at Karolinska Institutet

Publications -  102
Citations -  16438

Carsten O. Daub is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Cap analysis gene expression & Regulation of gene expression. The author has an hindex of 47, co-authored 97 publications receiving 14374 citations. Previous affiliations of Carsten O. Daub include April & Max Planck Society.

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An atlas of active enhancers across human cell types and tissues

TL;DR: It is shown that enhancers share properties with CpG-poor messenger RNA promoters but produce bidirectional, exosome-sensitive, relatively short unspliced RNAs, the generation of which is strongly related to enhancer activity.
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A promoter-level mammalian expression atlas

Alistair R. R. Forrest, +280 more
- 27 Mar 2014 - 
TL;DR: For example, the authors mapped transcription start sites (TSSs) and their usage in human and mouse primary cells, cell lines and tissues to produce a comprehensive overview of mammalian gene expression across the human body.
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An atlas of human long non-coding RNAs with accurate 5′ ends

TL;DR: This work integrates multiple transcript collections to generate a comprehensive atlas of 27,919 human lncRNA genes with high-confidence 5′ ends and expression profiles across 1,829 samples from the major human primary cell types and tissues, identifying 19,175 potentially functional lncRNAs in the human genome.
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The mutual information: detecting and evaluating dependencies between variables.

TL;DR: The findings show that the algorithms used so far may be quite substantially improved upon when dealing with small datasets, finite sample effects and other sources of potentially misleading results have to be taken into account.