P
Philip Mertins
Publications - 3
Citations - 506
Philip Mertins is an academic researcher. The author has contributed to research in topics: Cancer & Proteogenomics. The author has an hindex of 3, co-authored 3 publications receiving 256 citations.
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Journal ArticleDOI
Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities.
Suhas Vasaikar,Chen Huang,Xiaojing Wang,Vladislav A. Petyuk,Sara R. Savage,Bo Wen,Yongchao Dou,Yun Zhang,Zhiao Shi,Osama A. Arshad,Marina A. Gritsenko,Lisa J. Zimmerman,Jason E. McDermott,Therese R. W. Clauss,Ronald J. Moore,Rui Zhao,Matthew E. Monroe,Yi-Ting Wang,Matthew C. Chambers,Robbert J.C. Slebos,Ken S. Lau,Qianxing Mo,Li Ding,Matthew J. Ellis,Mathangi Thiagarajan,Christopher R. Kinsinger,Henry Rodriguez,Richard D. Smith,Karin D. Rodland,Karin D. Rodland,Daniel C. Liebler,Tao Liu,Bing Zhang,Akhilesh Pandey,Amanda G. Paulovich,Andrew N. Hoofnagle,D. R. Mani,Daniel W. Chan,David F. Ransohoff,David Fenyö,David L. Tabb,Douglas A. Levine,Emily S. Boja,Eric Kuhn,Forest M. White,Gordon Whiteley,Heng Zhu,Hui Zhang,Ie Ming Shih,Jasmin H. Bavarva,Jeffrey R. Whiteaker,Karen A. Ketchum,Karl R. Clauser,Kelly V. Ruggles,Kimberly Elburn,Linda Hannick,Mark A. Watson,Mauricio Oberti,Mehdi Mesri,Melinda E. Sanders,Melissa Borucki,Michael A. Gillette,Michael Snyder,Nathan Edwards,Negin Vatanian,Paul A. Rudnick,Peter B. McGarvey,Philip Mertins,R. Reid Townsend,Ratna R. Thangudu,Robert Rivers,Samuel H. Payne,Sherri R. Davies,Shuang Cai,Stephen E. Stein,Steven A. Carr,Steven J. Skates,Subha Madhavan,Tara Hiltke,Xian Chen,Yingming Zhao,Yue Wang,Zhen Zhang +82 more
TL;DR: Comparative proteomic and phosphoproteomic analysis of paired tumor and normal adjacent tissues produced a catalog of colon cancer-associated proteins and phosphosites, including known and putative new biomarkers, drug targets, and cancer/testis antigens, which suggested glycolysis as a potential target to overcome the resistance of MSI-H tumors to immune checkpoint blockade.
Journal ArticleDOI
Integrated Proteomic and Glycoproteomic Characterization of Human High-Grade Serous Ovarian Carcinoma
Yingwei Hu,Jianbo Pan,Punit Shah,Minghui Ao,Stefani N. Thomas,Yang Liu,Lijun Chen,Michael Schnaubelt,David J. Clark,Henry Rodriguez,Emily S. Boja,Tara Hiltke,Christopher R. Kinsinger,Karin D. Rodland,Qing Kay Li,Jiang Qian,Zhen Zhang,Daniel W. Chan,Hui Zhang,Akhilesh Pandey,Amanda G. Paulovich,Andrew N. Hoofnagle,Bing Zhang,D. R. Mani,Daniel C. Liebler,David F. Ransohoff,David Fenyö,David L. Tabb,Douglas A. Levine,Eric Kuhn,Forest M. White,Gordon Whiteley,Heng Zhu,Ie Ming Shih,Jasmin H. Bavarva,Jason E. McDermott,Jeffrey R. Whiteaker,Karen A. Ketchum,Karl R. Clauser,Kelly V. Ruggles,Kimberly Elburn,Li Ding,Linda Hannick,Lisa J. Zimmerman,Mark A. Watson,Mathangi Thiagarajan,Matthew J. Ellis,Mauricio Oberti,Mehdi Mesri,Melinda E. Sanders,Melissa Borucki,Michael A. Gillette,Michael Snyder,Nathan Edwards,Negin Vatanian,Paul A. Rudnick,Peter B. McGarvey,Philip Mertins,Raymond R. Townsend,Ratna R. Thangudu,Richard D. Smith,Robert Rivers,Robert J.C. Slebos,Samuel H. Payne,Sherri R. Davies,Shuang Cai,Stephen E. Stein,Steven A. Carr,Steven J. Skates,Subha Madhavan,Tao Liu,Xian Chen,Yingming Zhao,Yue Wang,Zhiao Shi +74 more
TL;DR: Insight is provided into the potential roles of glycosylation in the pathogenesis of HGSC, with the possibility of distinguishing pathological outcomes of ovarian tumors from non-tumors, as well as classifying tumor clusters.