J
Jason E. McDermott
Researcher at Pacific Northwest National Laboratory
Publications - 150
Citations - 10011
Jason E. McDermott is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Proteomics & Gene. The author has an hindex of 41, co-authored 142 publications receiving 7457 citations. Previous affiliations of Jason E. McDermott include United States Department of Energy & Institute for Systems Biology.
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Journal ArticleDOI
Proteogenomic characterization of human colon and rectal cancer
Bing Zhang,Jing Wang,Xiaojing Wang,Jing Zhu,Qi Liu,Zhiao Shi,Matthew C. Chambers,Lisa J. Zimmerman,Kent Shaddox,Sangtae Kim,Sherri R. Davies,Sean Wang,Pei Wang,Christopher R. Kinsinger,Robert Rivers,Henry Rodriguez,R. Reid Townsend,Matthew J. Ellis,Steven A. Carr,Steven A. Carr,David L. Tabb,Robert J. Coffey,Robbert J.C. Slebos,Daniel C. Liebler,Michael A. Gillette,Karl R. Klauser,Eric Kuhn,D. R. Mani,Philipp Mertins,Karen A. Ketchum,Amanda G. Paulovich,Jeffrey R. Whiteaker,Nathan Edwards,Peter B. McGarvey,Subha Madhavan,Daniel W. Chan,Akhilesh Pandey,Ie Ming Shih,Hui Zhang,Zhen Zhang,Heng Zhu,Gordon Whiteley,Steven J. Skates,Forest M. White,Douglas A. Levine,Emily S. Boja,Tara Hiltke,Mehdi Mesri,Kenna M. Shaw,Stephen E. Stein,David Fenyö,Tao Liu,Jason E. McDermott,Samuel H. Payne,Karin D. Rodland,Richard D. Smith,Paul A. Rudnick,Michael Snyder,Yingming Zhao,Xian Chen,David F. Ransohoff,Andrew N. Hoofnagle,Melinda E. Sanders,Yue Wang,Li Ding +64 more
TL;DR: Integrated proteogenomic analysis provides functional context to interpret genomic abnormalities and affords a new paradigm for understanding cancer biology.
Journal ArticleDOI
The Genomes of Oryza sativa: a history of duplications.
Jun Yu,Jun Yu,Jun Wang,Jun Wang,Wei Lin,Songgang Li,Songgang Li,Heng Li,Heng Li,Jun Zhou,Peixiang Ni,Wei Dong,Songnian Hu,Changqing Zeng,Jianguo Zhang,Yong Zhang,Yong Zhang,Ruiqiang Li,Zuyuan Xu,Shengting Li,Xianran Li,Hongkun Zheng,Lijuan Cong,Liang Lin,Jianning Yin,Jianing Geng,Guangyuan Li,Jianping Shi,Juan Liu,Hong Lv,Jun Li,Jing Wang,Jing Wang,Yajun Deng,Longhua Ran,Xiaoli Shi,Xiaoli Shi,Xiyin Wang,Xiyin Wang,Qingfa Wu,Changfeng Li,Xiaoyu Ren,Jingqiang Wang,Xiaoling Wang,Dawei Li,Dongyuan Liu,Xiaowei Zhang,Zhendong Ji,Wenming Zhao,Yongqiao Sun,Zhenpeng Zhang,Jingyue Bao,Yujun Han,Lingli Dong,Jia Ji,Peng Chen,Shuming Wu,Jinsong Liu,Ying Xiao,Dongbo Bu,Jianlong Tan,Li Yang,Chen Ye,Jingfen Zhang,Jingyi Xu,Yan Zhou,Yingpu Yu,Bing Zhang,Shulin Zhuang,Haibin Wei,Bin Liu,Meng Lei,Hong Yu,Yuanzhe Li,Hao Xu,Shulin Wei,Ximiao He,Lijun Fang,Zengjin Zhang,Yunze Zhang,Xiangang Huang,Zhixi Su,Wei Tong,Jinhong Li,Zongzhong Tong,Shuangli Li,Jia Ye,Lishun Wang,Lin Fang,Tingting Lei,Chen Chen,Huan Chen,Zhao Xu,Haihong Li,Haiyan Huang,Feng Zhang,Huayong Xu,Na Li,Caifeng Zhao,Shuting Li,Lijun Dong,Yanqing Huang,Long Li,Yan Xi,Qiuhui Qi,Wenjie Li,Bo Zhang,Wei Hu,Yanling Zhang,Xiangjun Tian,Yongzhi Jiao,Xiaohu Liang,Jiao Jin,Jiao Jin,Lei Gao,Lei Gao,Wei-Mou Zheng,Wei-Mou Zheng,Bailin Hao,Bailin Hao,Siqi Liu,Siqi Liu,Wen Wang,Wen Wang,Longping Yuan,Mengliang Cao,Jason E. McDermott,Ram Samudrala,Jian Wang,Jian Wang,Gane Ka-Shu Wong,Gane Ka-Shu Wong,Gane Ka-Shu Wong,Huanming Yang,Huanming Yang +134 more
TL;DR: A more inclusive new approach for analyzing duplication history is introduced here, which reveals an ancient whole-genome duplication, a recent segmental duplication on Chromosomes 11 and 12, and massive ongoing individual gene duplications.
Journal ArticleDOI
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Hui Zhang,Tao Liu,Zhen Zhang,Samuel H. Payne,Bai Zhang,Jason E. McDermott,Jian-Ying Zhou,Vladislav A. Petyuk,Li Chen,Debjit Ray,Shisheng Sun,Feng Yang,Lijun Chen,Jing Wang,Punit Shah,Seong Won Cha,Paul Aiyetan,Sunghee Woo,Yuan Tian,Marina A. Gritsenko,Therese R. W. Clauss,Caitlin H. Choi,Matthew E. Monroe,Stefani N. Thomas,Song Nie,Chaochao Wu,Ronald J. Moore,Kun-Hsing Yu,David L. Tabb,David Fenyö,Vineet Bafna,Yue Wang,Henry Rodriguez,Emily S. Boja,Tara Hiltke,Robert Rivers,Lori J. Sokoll,Heng Zhu,Ie Ming Shih,Leslie Cope,Akhilesh Pandey,Bing Zhang,Michael Snyder,Douglas A. Levine,Richard D. Smith,Daniel W. Chan,Karin D. Rodland,Steven A. Carr,Michael A. Gillette,Karl R. Klauser,Eric Kuhn,D. R. Mani,Philipp Mertins,Karen A. Ketchum,Ratna R. Thangudu,Shuang Cai,Mauricio Oberti,Amanda G. Paulovich,Jeffrey R. Whiteaker,Nathan Edwards,Peter B. McGarvey,Subha Madhavan,Pei Wang,Gordon Whiteley,Steven J. Skates,Forest M. White,Christopher R. Kinsinger,Mehdi Mesri,Kenna M. Shaw,Stephen E. Stein,Paul A. Rudnick,Michael Snyder,Yingming Zhao,Xian Chen,David F. Ransohoff,Andrew N. Hoofnagle,Daniel C. Liebler,Melinda E. Sanders,Zhiao Shi,Robbert J.C. Slebos,Lisa J. Zimmerman,Sherri R. Davies,Li Ding,Matthew J. Ellis,R. Reid Townsend +84 more
TL;DR: A view of how the somatic genome drives the cancer proteome and associations between protein and post-translational modification levels and clinical outcomes in HGSC is provided.
Journal ArticleDOI
Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors
Thomas Duhen,Rebekka Duhen,Ryan Montler,Jake Moses,Tarsem Moudgil,Noel F C C de Miranda,Cheri P. Goodall,Tiffany C. Blair,Bernard A. Fox,Jason E. McDermott,Shu Ching Chang,Gary L. Grunkemeier,Rom Leidner,R.B. Bell,Andrew D. Weinberg +14 more
TL;DR: The authors show that CD39 and CD103 mark a subset of tumor-infiltrating CD8 T cells that are tumor-reactive and exhibit characteristics of exhausted or tissue-resident memory T cells, which may lead to future adoptive T-cell cancer therapies.
Journal ArticleDOI
Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities.
Suhas Vasaikar,Chen Huang,Xiaojing Wang,Vladislav A. Petyuk,Sara R. Savage,Bo Wen,Yongchao Dou,Yun Zhang,Zhiao Shi,Osama A. Arshad,Marina A. Gritsenko,Lisa J. Zimmerman,Jason E. McDermott,Therese R. W. Clauss,Ronald J. Moore,Rui Zhao,Matthew E. Monroe,Yi-Ting Wang,Matthew C. Chambers,Robbert J.C. Slebos,Ken S. Lau,Qianxing Mo,Li Ding,Matthew J. Ellis,Mathangi Thiagarajan,Christopher R. Kinsinger,Henry Rodriguez,Richard D. Smith,Karin D. Rodland,Karin D. Rodland,Daniel C. Liebler,Tao Liu,Bing Zhang,Akhilesh Pandey,Amanda G. Paulovich,Andrew N. Hoofnagle,D. R. Mani,Daniel W. Chan,David F. Ransohoff,David Fenyö,David L. Tabb,Douglas A. Levine,Emily S. Boja,Eric Kuhn,Forest M. White,Gordon Whiteley,Heng Zhu,Hui Zhang,Ie Ming Shih,Jasmin H. Bavarva,Jeffrey R. Whiteaker,Karen A. Ketchum,Karl R. Clauser,Kelly V. Ruggles,Kimberly Elburn,Linda Hannick,Mark A. Watson,Mauricio Oberti,Mehdi Mesri,Melinda E. Sanders,Melissa Borucki,Michael A. Gillette,Michael Snyder,Nathan Edwards,Negin Vatanian,Paul A. Rudnick,Peter B. McGarvey,Philip Mertins,R. Reid Townsend,Ratna R. Thangudu,Robert Rivers,Samuel H. Payne,Sherri R. Davies,Shuang Cai,Stephen E. Stein,Steven A. Carr,Steven J. Skates,Subha Madhavan,Tara Hiltke,Xian Chen,Yingming Zhao,Yue Wang,Zhen Zhang +82 more
TL;DR: Comparative proteomic and phosphoproteomic analysis of paired tumor and normal adjacent tissues produced a catalog of colon cancer-associated proteins and phosphosites, including known and putative new biomarkers, drug targets, and cancer/testis antigens, which suggested glycolysis as a potential target to overcome the resistance of MSI-H tumors to immune checkpoint blockade.