V
Vladislav A. Petyuk
Researcher at Pacific Northwest National Laboratory
Publications - 131
Citations - 8855
Vladislav A. Petyuk is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Medicine & Proteome. The author has an hindex of 40, co-authored 109 publications receiving 5960 citations. Previous affiliations of Vladislav A. Petyuk include Environmental Molecular Sciences Laboratory & University of California, Los Angeles.
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Journal ArticleDOI
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Hui Zhang,Tao Liu,Zhen Zhang,Samuel H. Payne,Bai Zhang,Jason E. McDermott,Jian-Ying Zhou,Vladislav A. Petyuk,Li Chen,Debjit Ray,Shisheng Sun,Feng Yang,Lijun Chen,Jing Wang,Punit Shah,Seong Won Cha,Paul Aiyetan,Sunghee Woo,Yuan Tian,Marina A. Gritsenko,Therese R. W. Clauss,Caitlin H. Choi,Matthew E. Monroe,Stefani N. Thomas,Song Nie,Chaochao Wu,Ronald J. Moore,Kun-Hsing Yu,David L. Tabb,David Fenyö,Vineet Bafna,Yue Wang,Henry Rodriguez,Emily S. Boja,Tara Hiltke,Robert Rivers,Lori J. Sokoll,Heng Zhu,Ie Ming Shih,Leslie Cope,Akhilesh Pandey,Bing Zhang,Michael Snyder,Douglas A. Levine,Richard D. Smith,Daniel W. Chan,Karin D. Rodland,Steven A. Carr,Michael A. Gillette,Karl R. Klauser,Eric Kuhn,D. R. Mani,Philipp Mertins,Karen A. Ketchum,Ratna R. Thangudu,Shuang Cai,Mauricio Oberti,Amanda G. Paulovich,Jeffrey R. Whiteaker,Nathan Edwards,Peter B. McGarvey,Subha Madhavan,Pei Wang,Gordon Whiteley,Steven J. Skates,Forest M. White,Christopher R. Kinsinger,Mehdi Mesri,Kenna M. Shaw,Stephen E. Stein,Paul A. Rudnick,Michael Snyder,Yingming Zhao,Xian Chen,David F. Ransohoff,Andrew N. Hoofnagle,Daniel C. Liebler,Melinda E. Sanders,Zhiao Shi,Robbert J.C. Slebos,Lisa J. Zimmerman,Sherri R. Davies,Li Ding,Matthew J. Ellis,R. Reid Townsend +84 more
TL;DR: A view of how the somatic genome drives the cancer proteome and associations between protein and post-translational modification levels and clinical outcomes in HGSC is provided.
Journal ArticleDOI
Comparative Analysis of Proteome and Transcriptome Variation in Mouse
Anatole Ghazalpour,Brian J. Bennett,Vladislav A. Petyuk,Luz D. Orozco,Raffi Hagopian,Imran N. Mungrue,Charles R. Farber,Janet S. Sinsheimer,Hyun Min Kang,Nicholas A. Furlotte,Christopher C. Park,Ping Zi Wen,Heather M. Brewer,Karl K. Weitz,David G. Camp,Calvin Pan,Roumyana Yordanova,Isaac M. Neuhaus,Charles Tilford,Nathan O. Siemers,Peter S. Gargalovic,Eleazar Eskin,Todd G. Kirchgessner,Desmond J. Smith,Richard D. Smith,Aldons J. Lusis +25 more
TL;DR: Using correlation analysis, it is found that a low number of clinical trait relationships are preserved between the protein and mRNA gene products and that the majority of such relationships are specific to either the protein levels or transcript levels.
Journal ArticleDOI
Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
Erik C. B. Johnson,Eric B. Dammer,Duc M. Duong,Lingyan Ping,Maotian Zhou,Luming Yin,Lenora Higginbotham,Andrew Guajardo,Bartholomew White,Juan C. Troncoso,Madhav Thambisetty,Thomas J. Montine,Edward B. Lee,John Q. Trojanowski,Thomas G. Beach,Eric M. Reiman,Vahram Haroutunian,Vahram Haroutunian,Minghui Wang,Eric E. Schadt,Bin Zhang,Dennis W. Dickson,Nilufer Ertekin-Taner,Todd E. Golde,Vladislav A. Petyuk,Philip L. De Jager,David A. Bennett,Thomas S. Wingo,Srikant Rangaraju,Ihab Hajjar,Joshua M. Shulman,James J. Lah,Allan I. Levey,Nicholas T. Seyfried +33 more
TL;DR: Large-scale, comprehensive proteomic profiling of Alzheimer’s disease brain and cerebrospinal fluid reveals disease-associated protein coexpression modules and highlights the importance of glia and energy metabolism in disease pathogenesis.
Journal ArticleDOI
Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities.
Suhas Vasaikar,Chen Huang,Xiaojing Wang,Vladislav A. Petyuk,Sara R. Savage,Bo Wen,Yongchao Dou,Yun Zhang,Zhiao Shi,Osama A. Arshad,Marina A. Gritsenko,Lisa J. Zimmerman,Jason E. McDermott,Therese R. W. Clauss,Ronald J. Moore,Rui Zhao,Matthew E. Monroe,Yi-Ting Wang,Matthew C. Chambers,Robbert J.C. Slebos,Ken S. Lau,Qianxing Mo,Li Ding,Matthew J. Ellis,Mathangi Thiagarajan,Christopher R. Kinsinger,Henry Rodriguez,Richard D. Smith,Karin D. Rodland,Karin D. Rodland,Daniel C. Liebler,Tao Liu,Bing Zhang,Akhilesh Pandey,Amanda G. Paulovich,Andrew N. Hoofnagle,D. R. Mani,Daniel W. Chan,David F. Ransohoff,David Fenyö,David L. Tabb,Douglas A. Levine,Emily S. Boja,Eric Kuhn,Forest M. White,Gordon Whiteley,Heng Zhu,Hui Zhang,Ie Ming Shih,Jasmin H. Bavarva,Jeffrey R. Whiteaker,Karen A. Ketchum,Karl R. Clauser,Kelly V. Ruggles,Kimberly Elburn,Linda Hannick,Mark A. Watson,Mauricio Oberti,Mehdi Mesri,Melinda E. Sanders,Melissa Borucki,Michael A. Gillette,Michael Snyder,Nathan Edwards,Negin Vatanian,Paul A. Rudnick,Peter B. McGarvey,Philip Mertins,R. Reid Townsend,Ratna R. Thangudu,Robert Rivers,Samuel H. Payne,Sherri R. Davies,Shuang Cai,Stephen E. Stein,Steven A. Carr,Steven J. Skates,Subha Madhavan,Tara Hiltke,Xian Chen,Yingming Zhao,Yue Wang,Zhen Zhang +82 more
TL;DR: Comparative proteomic and phosphoproteomic analysis of paired tumor and normal adjacent tissues produced a catalog of colon cancer-associated proteins and phosphosites, including known and putative new biomarkers, drug targets, and cancer/testis antigens, which suggested glycolysis as a potential target to overcome the resistance of MSI-H tumors to immune checkpoint blockade.
Journal ArticleDOI
DAnTE: a statistical tool for quantitative analysis of -omics data
Ashoka D. Polpitiya,Wei-Jun Qian,Navdeep Jaitly,Vladislav A. Petyuk,Joshua N. Adkins,David G. Camp,Gordon A. Anderson,Richard D. Smith +7 more
TL;DR: DAnTE features selected normalization methods, missing value imputation algorithms, peptide-to-protein rollup methods, an extensive array of plotting functions and a comprehensive hypothesis-testing scheme that can handle unbalanced data and random effects.