Pierre Tissieres

TL;DR: A large cohort of international experts was able to achieve consensus regarding many recommendations for the best care of children with sepsis, acknowledging that most aspects of care had relatively low quality of evidence resulting in the frequent issuance of weak recommendations.

TL;DR: A large cohort of international experts was able to achieve consensus regarding many recommendations for the best care of children with sepsis, acknowledging that most aspects of care had relatively low quality of evidence resulting in the frequent issuance of weak recommendations.

TL;DR: Anakinra did not improve outcomes in patients with mild-to-moderate COVID-19 pneumonia, and further studies are needed to assess the efficacy of anakinra in other selected groups of patients with more severe CO VID-19.

TL;DR: This Position Paper provides the first consensus definition for neonatal ARDS (called the Montreux definition), and provides expert consensus that mechanisms causing ARDS in adults and older children-namely complex surfactant dysfunction, lung tissue inflammation, loss of lung volume, increased shunt, and diffuse alveolar damage-are also present in several critical neonatal respiratory disorders.

TL;DR: BD validity for children is similar to that already reported in adults and mainly due to the introduction of a “severe ARDS” category.