P
Ping Yuan
Researcher at Sun Yat-sen University
Publications - 40
Citations - 3788
Ping Yuan is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Embryonic stem cell & Cellular differentiation. The author has an hindex of 14, co-authored 35 publications receiving 3437 citations. Previous affiliations of Ping Yuan include Institute of Molecular and Cell Biology & Memorial Hospital of South Bend.
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Journal ArticleDOI
Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells
Xi Chen,Han Xu,Ping Yuan,Fang Fang,Fang Fang,Mikael Huss,Vinsensius B. Vega,Eleanor Wong,Yuriy L. Orlov,Weiwei Zhang,Weiwei Zhang,Jianming Jiang,Jianming Jiang,Yuin-Han Loh,Yuin-Han Loh,Hock Chuan Yeo,Zhen Xuan Yeo,Vipin Narang,Kunde R Govindarajan,Bernard Leong,Atif Shahab,Yijun Ruan,Guillaume Bourque,Wing-Kin Sung,Neil D. Clarke,Chia-Lin Wei,Huck-Hui Ng,Huck-Hui Ng +27 more
TL;DR: This study uses chromatin immunoprecipitation coupled with ultra-high-throughput DNA sequencing to map the locations of TF-binding sites and identifies important features of the transcriptional regulatory networks that define ES-cell identity.
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Tbx3 improves the germ-line competency of induced pluripotent stem cells
Jianyong Han,Ping Yuan,Henry Yang,Jinqiu Zhang,Boon Seng Soh,Pin Li,Siew Lan Lim,Suying Cao,Junliang Tay,Yuriy L. Orlov,Thomas Lufkin,Huck-Hui Ng,Wai Leong Tam,Bing Lim +13 more
TL;DR: iPS cells generated with OSK and Tbx3 (OSKT) are superior in both germ-cell contribution to the gonads and germ-line transmission frequency, and the need to rigorously characterize iPS cells beyond in vitro studies is highlighted.
Journal ArticleDOI
Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
Ping Yuan,Jianyong Han,Guoji Guo,Yuriy L. Orlov,Mikael Huss,Yuin-Han Loh,Lai-Ping Yaw,Paul Robson,Bing Lim,Huck-Hui Ng +9 more
TL;DR: The results suggest that Eset restricts the extraembryonic trophoblast lineage potential of pluripotent cells and links an epigenetic regulator to key cell fate decision through a pluripotency factor.
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Hedgehog signaling induces osteosarcoma development through Yap1 and H19 overexpression.
TL;DR: It is demonstrated that aberrant Hh signaling in mature osteoblasts is responsible for the pathogenesis of osteoblastic osteosarcoma through Yap1 and H19 overexpression.
Journal ArticleDOI
A Dimerized Coiled-Coil Domain and an Adjoining Part of Geminin Interact with Two Sites on Cdt1 for Replication Inhibition
Sandeep Saxena,Ping Yuan,Suman Kumar Dhar,Takeshi Senga,David Y. Takeda,Howard Robinson,Sally Kornbluth,Kunchithapadam Swaminathan,Kunchithapadam Swaminathan,Anindya Dutta +9 more
TL;DR: It is reported that geminin forms a parallel coiled-coil homodimer with atypical residues in the dimer interface, which is a critical component of a bipartite interaction interface between geminIn and its cellular targets.