Q
Quan Chen
Researcher at Nankai University
Publications - 244
Citations - 20608
Quan Chen is an academic researcher from Nankai University. The author has contributed to research in topics: Medicine & Mitochondrion. The author has an hindex of 52, co-authored 154 publications receiving 16697 citations. Previous affiliations of Quan Chen include Chinese Academy of Fishery Sciences & Chinese Academy of Sciences.
Papers
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Journal ArticleDOI
Visceral Adiposity, Inflammation, and Testosterone Predict Skeletal Muscle Mitochondrial Mass and Activity in Chronic Spinal Cord Injury
Jacob A. Goldsmith,Raymond E Lai,Ryan S. Garten,Quan Chen,Edward J. Lesnefsky,Robert A. Perera,Ashraf S. Gorgey +6 more
TL;DR: Increased visceral adiposity and associated inflammatory signaling (CRP) along with reduced testosterone levels predict mitochondrial dysfunction following SCI, and lower VATCSA and higher testosterone levels or lower VATSSA and lower CRP levels positively predict mitochondrial mass and enzyme activity in persons with chronic SCI.
Patent
Anti-cellular-prion-protein monoclonal antibody and application of in diagnostic test kit
TL;DR: In this article, an anti-cellular-prion-protein monoclonal antibody was used for detecting rectal cancer or metastatic cancer stem cells using a diagnostic test kit.
Journal ArticleDOI
Optical Biosensors and Their Applications for the Detection of Water Pollutants
Marcela Herrera-Domínguez,Gesuri Morales-Luna,Jürgen Mahlknecht,Quan Chen,Iris Aguilar-Hernández,Nancy Ornelas-Soto +5 more
TL;DR: In this paper , a review of the most recent work in the specific area of optical biosensing for water monitoring is presented, focusing on both the biological element and the transducer used, as well as the type of target contaminant.
Journal ArticleDOI
Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function
Linbo Chen,Qian-Ru Zhang,Yuanyuan Meng,Tian Zhao,Chenglong Mu,Changying Fu,Caijuan Deng,Jianyu Feng,Siling Du,Wei Liu,Guangfeng Geng,Kaili Ma,Hongcheng Cheng,Qiangqiang Liu,Qian Luo,Jiaojiao Zhang,Zhanqiang Du,Lin Cao,Hui Yan Wang,Yong Liu,Jianping Lin,Guo Chen,Lei Liu,Sin Man Lam,Guanghou Shui,Yushan Zhu,Quan Chen +26 more
TL;DR: In this paper , the authors show that saturated dietary fatty acids such as palmitic acid, but not unsaturated oleic acid (OA), increase lysophosphatidylinositol (LPI) production to impact on the stability of the mitophagy receptor FUNDC1 and on mitochondrial quality.
Journal ArticleDOI
The determination of Sulfobutylether β-Cyclodextrin Sodium (SBECD) by LC-MS/MS and its application in remdesivir pharmacokinetics study for pediatric patients.
Zhengdong Yang,Deqing Xiao,Kah-Hiing John Ling,Thomas L. Tarnowski,Rita Humeniuk,Bryan Parmentier,Y. Fu,Eric Johnson,Marsha Luna,Habibi Goudarzi,Quan Chen +10 more
TL;DR: In this paper , an LC-MS/MS method was developed and validated for specific, accurate, and precise determination of SBECD concentrations in human plasma, which was applied to determine SBECD levels in plasma samples collected from pediatric patients during RDV clinical studies.