Q
Quan Chen
Researcher at Nankai University
Publications - 244
Citations - 20608
Quan Chen is an academic researcher from Nankai University. The author has contributed to research in topics: Medicine & Mitochondrion. The author has an hindex of 52, co-authored 154 publications receiving 16697 citations. Previous affiliations of Quan Chen include Chinese Academy of Fishery Sciences & Chinese Academy of Sciences.
Papers
More filters
Journal ArticleDOI
Redox Regulation of Apoptosis before and after Cytochrome C Release
TL;DR: This review summarizes what is known about the biological role of ROS and its targets in apoptosis with an emphasis on its intricate connections to mitochondria and the basic components of cell death.
Journal ArticleDOI
Caveolin-1 negatively regulates TRAIL-induced apoptosis in human hepatocarcinoma cells
Xiangxuan Zhao,Yong Liu,Qi Ma,Xiaohui Wang,Haijing Jin,Maryam Mehrpour,Maryam Mehrpour,Quan Chen,Quan Chen +8 more
TL;DR: The results reveal a new mechanism by which caveolin-1 negatively regulates TRAIL-induced apoptosis in human hepatocarcinoma cells.
Book ChapterDOI
Monitoring mitophagy in mammalian cells.
TL;DR: This work focuses on the current techniques that have been used to monitor mitophagy in mammalian cells, including morphological and biochemical parameters for monitoring the occurrence ofMitophagy.
Journal ArticleDOI
Mitophagy receptor FUNDC1 is regulated by PGC-1α/NRF1 to fine tune mitochondrial homeostasis
Lei Liu,Yanjun Li,Jianing Wang,Di Zhang,Di Zhang,Hao Wu,Wenhui Li,Huifang Wei,Na Ta,Yuyuan Fan,Yujiao Liu,Xiaohui Wang,Jun Wang,Xin Pan,Xudong Liao,Yushan Zhu,Quan Chen +16 more
TL;DR: In this paper, PGC-1α and nuclear respiratory factor 1 (NRF1), master regulators of mitochondrial biogenesis and metabolic adaptation, also transcriptionally upregulate the gene encoding FUNDC1, a previously characterized mitophagy receptor.
Journal ArticleDOI
Uncoupling protein 2 protects testicular germ cells from hyperthermia-induced apoptosis.
Keying Zhang,Yingli Shang,Shangying Liao,Wei Zhang,Hong Nian,Yi-Xun Liu,Quan Chen,Chunsheng Han +7 more
TL;DR: It is proposed that UCP2 may represent an effective weaponry used by germ cells to combat ROS-induced apoptosis and was detected in all germ cells with its level significantly increased if the testes were exposed to 43 degrees C for 5 min.