R
Raphael Guerois
Researcher at Université Paris-Saclay
Publications - 141
Citations - 6919
Raphael Guerois is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Homologous recombination & DNA repair. The author has an hindex of 41, co-authored 129 publications receiving 6001 citations. Previous affiliations of Raphael Guerois include Centre national de la recherche scientifique & French Alternative Energies and Atomic Energy Commission.
Papers
More filters
Journal ArticleDOI
Unveiling Novel RecO Distant Orthologues Involved in Homologous Recombination
TL;DR: In insight into the mechanisms that this successful pathogen uses to generate genetic diversity and adapt to changing environments and new hosts, it is found that neither RecOR nor RecB contributes to transformation, suggesting the presence of a third, specialized, RecA-dependent pathway responsible for the integration of transforming DNA into the chromosome of this naturally competent bacteria.
Journal ArticleDOI
Versatility and invariance in the evolution of homologous heteromeric interfaces.
TL;DR: This study systematically and quantitatively analyzed the conservation of different types of interface contacts in protein-protein interactions and identifies two important interface descriptors which correlate with an increased conservation in the evolution of interfaces: apolar patches and contacts surrounding anchor residues.
Journal ArticleDOI
Protein design based on folding models.
Raphael Guerois,Luis Serrano +1 more
TL;DR: The basic rules governing the folding of small, single-domain proteins are being discovered and new algorithms that can predict the major features of the folding process give the opportunity to design and optimise protein folding in a rational way.
Journal ArticleDOI
Meet-U: Educating through research immersion.
Nika Abdollahi,Alexandre Albani,Eric Anthony,Agnes Baud,Mélissa Cardon,Robert Clerc,Dariusz Czernecki,Romain Conte,Laurent David,Agathe Delaune,Samia Djerroud,Pauline Fourgoux,Nadège Guiglielmoni,Jeanne Laurentie,Nathalie Lehmann,Camille Lochard,Rémi Montagne,Vasiliki Myrodia,Vaitea Opuu,Elise Parey,Lélia Polit,Sylvain Privé,Chloé Quignot,Maria Ruiz-Cuevas,Mariam Sissoko,Nicolas Sompairac,Audrey Vallerix,Violaine Verrecchia,Marc Delarue,Raphael Guerois,Yann Ponty,Sophie Sacquin-Mora,Alessandra Carbone,Christine Froidevaux,Stéphane Le Crom,Olivier Lespinet,Martin Weigt,Samer Abboud,Juliana S Bernardes,Guillaume Bouvier,Chloé Dequeker,Arnaud Ferré,Patrick F.J. Fuchs,Gaëlle Lelandais,Pierre Poulain,Hugues Richard,Hugo Schweke,Elodie Laine,Anne Lopes +48 more
TL;DR: A new educational initiative called Meet-U that aims to train students for collaborative work in computational biology and to bridge the gap between education and research, which is easy to implement and can be straightforwardly transferred to other fields and/or universities.
Journal ArticleDOI
The PHD finger protein Spp1 has distinct functions in the Set1 and the meiotic DSB formation complexes.
Céline Adam,Céline Adam,Raphael Guerois,Anna Citarella,Anna Citarella,Laura Verardi,Laura Verardi,Florine Adolphe,Florine Adolphe,Claire Béneut,Claire Béneut,Vérane Sommermeyer,Vérane Sommermeyer,Claire Ramus,Jérôme Govin,Yohann Couté,Valérie Borde,Valérie Borde +17 more
TL;DR: This work proposes a model where Spp1 works in three ways to promote recombination initiation: first by depositing histone H3K4 methylation (Set1 complex), next by “reading” and protecting histoneH3K 4 methylation, and finally by making the link with the chromosome axis (Mer2-Spp1 complex).