R
Raphael Guerois
Researcher at Université Paris-Saclay
Publications - 141
Citations - 6919
Raphael Guerois is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Homologous recombination & DNA repair. The author has an hindex of 41, co-authored 129 publications receiving 6001 citations. Previous affiliations of Raphael Guerois include Centre national de la recherche scientifique & French Alternative Energies and Atomic Energy Commission.
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Journal ArticleDOI
Direct interaction between exocyst and Wave complexes promotes cell protrusions and motility.
Marco Biondini,Marco Biondini,Amel Sadou-Dubourgnoux,Amel Sadou-Dubourgnoux,Perrine Paul-Gilloteaux,Perrine Paul-Gilloteaux,Giulia Zago,Giulia Zago,Melis D Arslanhan,Melis D Arslanhan,François Waharte,François Waharte,Etienne Formstecher,Maud Hertzog,Jinchao Yu,Raphael Guerois,Alexis Gautreau,Giorgio Scita,Jacques Camonis,Jacques Camonis,Maria Carla Parrini,Maria Carla Parrini +21 more
TL;DR: A direct link between exocyst and Wave complexes is revealed, providing new mechanistic insight into the spatio-temporal coordination between membrane trafficking and actin polymerization in cell migration.
Journal ArticleDOI
Exploring the folding pathways of annexin I, a multidomain protein. I. non-native structures stabilize the partially folded state of the isolated domain 2 of annexin I
Françoise Cordier-Ochsenbein,Raphael Guerois,Françoise Baleux,Tam Huynh-Dinh,Pierre-Noël Lirsac,Françoise Russo-Marie,Jean-Michel Neumann,Alain Sanson +7 more
TL;DR: In this article, a detailed analysis of the partially folded D2 domain was performed using 15N-1H multidimensional NMR, which revealed the existence of a sequence-encoded regulation of the folding pathways and kinetics.
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Rad52-Rad51 association is essential to protect Rad51 filaments against Srs2, but facultative for filament formation
Emilie Ma,Pauline Dupaigne,Pauline Dupaigne,Pauline Dupaigne,Laurent Maloisel,Raphael Guerois,Raphael Guerois,Eric Le Cam,Eric Le Cam,Eric Le Cam,Eric Coïc +10 more
TL;DR: It is found that Rad52-Rad51 association makes Rad51 filaments toxic in Srs2-deficient cells after exposure to DNA damaging agents, independently of Rad52 role in Rad51 filament assembly.
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Phagonaute: A web-based interface for phage synteny browsing and protein function prediction
TL;DR: The Phagonaute tool permits detections of co-occurrences, often indicative of proteins completing a task together, and observation of conserved patterns across large evolutionary distances, to help virologists in their quest for protein functions and evolutionary relationships.
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Patronus is the elusive plant securin, preventing chromosome separation by antagonizing separase
Laurence Cromer,Sylvie Jolivet,Dipesh Kumar Singh,Floriane Berthier,N. De Winne,G. De Jaeger,Shinichiro Komaki,Maria Ada Prusicki,Arp Schnittger,Raphael Guerois,Raphael Mercier +10 more
TL;DR: It is shown that PANS1 targeting by the anaphase-promoting complex is required to trigger chromosome separation, mirroring the regulation of securin, and identification of patronus as the elusive plant Securin illustrates the extreme sequence divergence of this central regulator of mitosis and meiosis.