R
Raphael Guerois
Researcher at Université Paris-Saclay
Publications - 141
Citations - 6919
Raphael Guerois is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Homologous recombination & DNA repair. The author has an hindex of 41, co-authored 129 publications receiving 6001 citations. Previous affiliations of Raphael Guerois include Centre national de la recherche scientifique & French Alternative Energies and Atomic Energy Commission.
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Journal ArticleDOI
Septin 9 has Two Polybasic Domains Critical to Septin Filament Assembly and Golgi Integrity
Mohyeddine Omrane,Amanda Souza Camara,Cyntia Taveneau,Nassima Benzoubir,Thibault Tubiana,Jinchao Yu,Raphael Guerois,Raphael Guerois,Didier Samuel,Didier Samuel,Bruno Goud,Christian Poüs,Christian Poüs,Stéphane Bressanelli,Richard Charles Garratt,Abdou Rachid Thiam,Ama Gassama-Diagne,Ama Gassama-Diagne +17 more
TL;DR: It is found that septin 9 has a second polybasic domain (PB2) conserved in the human septin family, and this finding offers further insight into the role of septins in organelle morphology.
Journal ArticleDOI
PPI4DOCK: large scale assessment of the use of homology models in free docking over more than 1000 realistic targets.
Jinchao Yu,Raphael Guerois +1 more
TL;DR: The PPI4DOCK benchmark contains a large set of realistic cases and provides new ground for assessing docking and scoring methodologies and explores how to benefit from comparative modelling of unbound subunits to expand docking benchmark datasets.
Journal ArticleDOI
Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation.
Aurore Sanchez,Aurore Sanchez,Aurore Sanchez,Céline Adam,Céline Adam,Felix Rauh,Yann Duroc,Yann Duroc,Lepakshi Ranjha,Bérangère Lombard,Xiaojing Mu,Xiaojing Mu,Mélody Wintrebert,Mélody Wintrebert,Damarys Loew,Alba Guarné,Stefano Gnan,Stefano Gnan,Chun-Long Chen,Chun-Long Chen,Scott Keeney,Scott Keeney,Petr Cejka,Raphael Guerois,Franz Klein,Jean-Baptiste Charbonnier,Valérie Borde,Valérie Borde +27 more
TL;DR: It is proposed that Exo1 serves as a central coordinator in this molecular interplay, providing a defined order of interaction that prevents deleterious, premature activation of crossovers.
Journal ArticleDOI
Disentangling the molecular determinants for Cenp‐F localization to nuclear pores and kinetochores
Alessandro Berto,Alessandro Berto,Jinchao Yu,Stéphanie Morchoisne-Bolhy,Chiara Bertipaglia,Richard B. Vallee,Julien Dumont,Françoise Ochsenbein,Raphael Guerois,Valérie Doye +9 more
TL;DR: This work generates an interaction model between a conserved helix within the Nup133 β‐propeller and a short leucine zipper‐containing dimeric segment of Cenp‐F and identifies Bub1 as the direct KT‐core binding partner of Cetochores.
Journal ArticleDOI
Stabilization of HIV-1 Envelope in the CD4-bound Conformation through Specific Cross-linking of a CD4 Mimetic
Grégoire Martin,Brian Burke,Robert Thai,Antu K. Dey,Olivier Combes,Bernadette Heyd,Anthony R. Geonnotti,David C. Montefiori,Elaine Kan,Ying Lian,Yide Sun,Toufik Abache,Jeffrey B. Ulmer,Hocine Madaoui,Raphael Guerois,Susan W. Barnett,Indresh K. Srivastava,Pascal Kessler,Loic Martin +18 more
TL;DR: Small sized CD4 mimetics (miniCD4s) that are poorly immunogenic and do not induce anti-CD4 antibodies represent potential vaccine candidates that mimic an important HIV fusion intermediate, without autoimmune hazard.