S
Stéphane Le Crom
Researcher at University of Paris
Publications - 63
Citations - 5116
Stéphane Le Crom is an academic researcher from University of Paris. The author has contributed to research in topics: Gene & Trichoderma reesei. The author has an hindex of 28, co-authored 62 publications receiving 4551 citations. Previous affiliations of Stéphane Le Crom include Pierre-and-Marie-Curie University & Centre national de la recherche scientifique.
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Journal ArticleDOI
A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis
Marie-Agnès Dillies,Andrea Rau,Julie Aubert,Christelle Hennequet-Antier,Marine Jeanmougin,Nicolas Servant,Céline Keime,Guillemette Marot,David Castel,Jordi Estellé,Gregory Guernec,Bernd Jagla,Luc Jouneau,Denis Laloë,Caroline Le Gall,Brigitte Schaeffer,Stéphane Le Crom,Mickaël Guedj,Florence Jaffrézic +18 more
TL;DR: This work focuses on a comprehensive comparison of seven recently proposed normalization methods for the differential analysis of RNA-seq data, with an emphasis on the use of varied real and simulated datasets involving different species and experimental designs to represent data characteristics commonly observed in practice.
Journal ArticleDOI
Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma
Christian P. Kubicek,Alfredo Herrera-Estrella,Verena Seidl-Seiboth,Diego Martinez,Irina S. Druzhinina,Michael R. Thon,Susanne Zeilinger,Sergio Casas-Flores,Benjamin A. Horwitz,Prasun K. Mukherjee,Mala Mukherjee,László Kredics,Luis David Alcaraz,Andrea Aerts,Zsuzsanna Antal,Lea Atanasova,Mayte G Cervantes-Badillo,Jean F. Challacombe,Olga Chertkov,Kevin McCluskey,Fanny Coulpier,Nandan P. Deshpande,Hans von Döhren,Daniel J. Ebbole,Edgardo Ulises Esquivel-Naranjo,Erzsébet Fekete,Michel Flipphi,Fabian Glaser,Elida Yazmin Gomez-Rodriguez,Sabine Gruber,Cliff Han,Bernard Henrissat,Rosa Hermosa,Miguel Ángel Hernández-Oñate,Levente Karaffa,Idit Kosti,Stéphane Le Crom,Erika Lindquist,Susan Lucas,Mette Lübeck,Peter Stephensen Lübeck,Antoine Margeot,Benjamin Metz,Monica Misra,Helena Nevalainen,Markus Omann,Nicolle H. Packer,Giancarlo Perrone,Edith Elena Uresti-Rivera,Asaf Salamov,Monika Schmoll,Bernhard Seiboth,Harris Shapiro,Serenella A. Sukno,Juan Antonio Tamayo-Ramos,Doris Tisch,Aric Wiest,Heather H. Wilkinson,Michael Zhang,Pedro M. Coutinho,Charles M. Kenerley,Enrique Monte,Scott E. Baker,Scott E. Baker,Igor V. Grigoriev +64 more
TL;DR: A better understanding of mycoparasitism is offered, and the development of improved biocontrol strains for efficient and environmentally friendly protection of plants is enforced.
Journal ArticleDOI
Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes
Silvia Ginés,Joëlle Hillion,Maria Torvinen,Stéphane Le Crom,Vicent Casadó,Enric I. Canela,Sofia Rondin,J.Y. Lew,Stanley J. Watson,Michele Zoli,Luigi F. Agnati,Philippe Vernier,Carmen Lluis,Sergi Ferré,Kjell Fuxe,Rafael Franco +15 more
TL;DR: The A(1)R/D( 1)R heteromerization may be one molecular basis for the demonstrated antagonistic modulation of A(2)R of D(1]R receptor signaling in the brain and seems to be essential for the blockade of A-1-R agonist-induced A(3)R-induced coclustering and for the desensitization of the D(0)R agonists cAMP accumulation.
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Comparative transcriptomics reveals different strategies of Trichoderma mycoparasitism
Lea Atanasova,Stéphane Le Crom,Sabine Gruber,Fanny Coulpier,Fanny Coulpier,Fanny Coulpier,Verena Seidl-Seiboth,Christian P. Kubicek,Irina S. Druzhinina +8 more
TL;DR: This genome-wide expression study demonstrates that the initial Trichoderma mycotrophy has differentiated into several alternative ecological strategies ranging from parasitism to predation and saprotrophy, and provides first insights into the mechanisms of interactions between Trichodma and other fungi that may be exploited for further development of biofungicides.
Journal ArticleDOI
Yeast Mitochondrial Biogenesis: A Role for the PUF RNA-Binding Protein Puf3p in mRNA Localization
Yann Saint-Georges,Mathilde Garcia,Thierry Delaveau,Laurent Jourdren,Stéphane Le Crom,Sophie Lemoine,Véronique Tanty,Frédéric Devaux,Claude Jacq +8 more
TL;DR: MLR, which is intimately linked to translation control, and the activity of mRNA-binding proteins like Puf3p, may provide the conditions for a fine spatiotemporal control of mitochondrial protein import and mitochondrial protein complex assembly.