R
Richard E. Champlin
Researcher at University of Texas MD Anderson Cancer Center
Publications - 1500
Citations - 73470
Richard E. Champlin is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 138, co-authored 1402 publications receiving 66917 citations.
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Control of graft-versus-host disease with maintenance of the graft-versus-leukemia effect in a murine allogeneic transplant model using retrovirally transduced murine suicidal lymphocytes.
Steven M. Kornblau,Preston G. Aycox,L. Clifton Stephens,David McCue,Richard E. Champlin,Frank C. Marini +5 more
TL;DR: Retrovirally transduced suicidal lymphocytes generate a potent GVL effect while simultaneously enabling control of GVHD, which results in improved leukemia and GV HD-free survival.
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Fractures frequently occur in older cancer patients: the MD Anderson Cancer Center experience
Beatrice J. Edwards,Ming Sun,Xiaotao Zhang,Holly M. Holmes,Juhee Song,Peter Khalil,Meghan Sri Karuturi,Jay B. Shah,Colin P.N. Dinney,Robert F. Gagel,Vicente Valero,Richard E. Champlin,Debasish Tripathy,William A. Murphy +13 more
TL;DR: Most older cancer patients studied have osteoporosis or low bone mass, resulting in an almost 3-fold increase in fracture risk as compared to epidemiologic studies.
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Cytogenetics and comorbidity predict outcomes in older myelodysplastic syndrome patients after allogeneic stem cell transplantation using reduced intensity conditioning
Orhan Kemal Yucel,Rima M. Saliba,Gabriella Rondon,Sairah Ahmed,Amin M. Alousi,Qaiser Bashir,Stefan O. Ciurea,Uday R. Popat,Isa Khouri,David Marin,Katy Rezvani,Partow Kebriaei,Elizabeth J. Shpall,Richard E. Champlin,Betul Oran +14 more
TL;DR: Allogeneic hematopoietic stem cell transplantation is the only treatment with a curative potential for myelodysplastic syndrome patients and its role for older MDS patients has yet to be defined.
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PET imaging of T cells derived from umbilical cord blood.
Harjeet Singh,Amer Najjar,Simon Olivares,Ryuichi Nishii,Uday Mukhopadhyay,Mian M. Alauddin,Pallavi R. Manuri,Helen Huls,Dean A. Lee,Gianpietro Dotti,Catherine M. Bollard,Paul J. Simmons,Elizabeth J. Shpall,Richard E. Champlin,Juri G. Gelovani,Laurence J.N. Cooper +15 more
TL;DR: Imaging provides a methodology for quantitative, non-invasive, longitudinal and spatial in vivo information about the dynamic processes of infused T cells.
Journal ArticleDOI
Allogeneic Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndromes
TL;DR: Hematopoietic transplantation remains the only curative treatment for patients with MDS and should be used before patients overtly progress to advanced disease, and novel transplantation approaches are required to reduce the risk of disease relapse and complications of the procedure.