R
Richard E. Champlin
Researcher at University of Texas MD Anderson Cancer Center
Publications - 1500
Citations - 73470
Richard E. Champlin is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 138, co-authored 1402 publications receiving 66917 citations.
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Journal ArticleDOI
The clinical impact of time to response in de novo accelerated-phase chronic myeloid leukemia
Maro Ohanian,Hagop M. Kantarjian,Mahran Shoukier,Sara Dellasala,Arine Musaelyan,Graciela M. Nogueras González,Elias Jabbour,Lynne V. Abruzzo,Srdan Verstovsek,Gautam Borthakur,Farhad Ravandi,Guillermo Garcia-Manero,Gevorg Tamamyan,Richard E. Champlin,Sherry Pierce,Alessandra Ferrajoli,Tapan M. Kadia,Jorge E. Cortes +17 more
TL;DR: In de novo CML‐AP, early response at 3 and 6 months is a strong determinant of long‐term outcome, and the impact of various degrees of molecular and cytogenetic response at early time points is determined.
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Syngeneic blood stem cell transplantation for infectious mononucleosis-related aplastic anaemia.
TL;DR: A 17‐year‐old girl developed severe aplastic anaemia following an episode of infectious mononucleosis and underwent mobilization with filgrastim and subsequent leukapheresis for blood stem cell collection, which led to durable trilineage haematological recovery still ongoing at 16 months after her second transplant.
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Haploidentical transplants for patients with relapse after the first allograft
Samer A. Srour,Piyanuch Kongtim,Piyanuch Kongtim,Gabriela Rondon,Julianne Chen,Demetrios Petropoulos,Jeremy Ramdial,Uday R. Popat,Partow Kebriaei,Muzaffar H. Qazilbash,Elizabeth J. Shpall,Richard E. Champlin,Stefan O. Ciurea,Stefan O. Ciurea +13 more
TL;DR: It is suggested that haploidentical grafts might be a preferred donor source for second AHSCT as these are high‐risk patients who frequently need to proceed urgently to transplant.
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Results of Bortezomib (BTZ) Therapy for Myeloma (MM) Patients Relapsing after an Allogeneic Transplant. Preliminary Results Show Efficacy without Induction of GVHD.
Sergio Giralt,Ana Aleman,Xin Lei,Marilyn S. Davis,Kerry Mickler,Donna M. Weber,Michael Wang,Richard E. Champlin +7 more
TL;DR: BTZ therapy is effective as treatment of MM relapse post allo SCT, it is well tolerated and does not promote GVHD reactions, and the response rates would seem to be higher than the responses reported to donor lymphocyte infusions in this setting.
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Pure red cell aplasia characterized by erythropoietic maturation arrest. Response to anti-thymocyte globulin.
TL;DR: A patient with maturation arrest of erythropoiesis at the basophilic normoblast stage who had a response to an eight-day course of anti-thymocyte globulin with a return of normal erythroblasts is described.