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Richard E. Champlin

Researcher at University of Texas MD Anderson Cancer Center

Publications -  1500
Citations -  73470

Richard E. Champlin is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 138, co-authored 1402 publications receiving 66917 citations.

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Pentostatin therapy for steroid-refractory acute graft versus host disease: identifying those who may benefit.

TL;DR: Pentostatin remains a viable treatment option for steroid-refractory (SR)-aGVHD, especially in patients 60 years or younger with isolated LGI involvement, and in patients <60 years witholated LGI GVHD with isolatedLGI involvement.
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Leukemia burden delays lymphocyte and platelet recovery after allo-SCT for AML.

TL;DR: The data showed that the presence of circulating blasts before transplantation is significantly correlated with low post-SCT day +30 ALC and slow platelet engraftment, suggesting that the impact of early A LC and platelet recovery on transplant outcome may not be independent of disease status at transplantation.
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Principles of bone marrow processing and progenitor cell/mononuclear cell concentrate collection in a continuous flow blood cell separation system.

TL;DR: A protocol for recovery of MNC, CD33+, CD34+, and CD34+/DR- cells from harvested marrow for autologous and allogeneic transplants using a continuous flow blood cell separator is developed, the variables influencing the recovery of the cells of interest and the clinical response to infusion of the processed cells are reported.