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Richard E. Champlin
Researcher at University of Texas MD Anderson Cancer Center
Publications - 1500
Citations - 73470
Richard E. Champlin is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 138, co-authored 1402 publications receiving 66917 citations.
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Journal ArticleDOI
Bone Marrow or Peripheral Blood for Reduced-Intensity Conditioning Unrelated Donor Transplantation
Mary Eapen,Brent R. Logan,Mary M. Horowitz,Xiaobo Zhong,Miguel-Angel Perales,Stephanie J. Lee,Vanderson Rocha,Robert J. Soiffer,Richard E. Champlin +8 more
TL;DR: Survival after transplantation of PB and BM are comparable in the setting of nonirradiation RIC regimens for hematologic malignancy, and the effect of GVHD prophylaxis on survival merits further evaluation.
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Bone marrow transplantation using unrelated donors for patients with advanced leukemia or bone marrow failure
James L. Gajewski,Winston G. Ho,Stephen A. Feig,Lynne Hunt,Nancy Kaufman,Richard E. Champlin +5 more
TL;DR: Closely matched unrelated donor bone marrow transplants are associated with a higher incidence of graft failure and graft-versus-host disease than typically reported for transplants from HLA-identical siblings, but these preliminary data suggest a lower rate of relapse.
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Haploidentical Transplantation with Post-Transplantation Cyclophosphamide for High-Risk Acute Lymphoblastic Leukemia
Samer A. Srour,Samer A. Srour,Denái R. Milton,Asad Bashey,Amado J Karduss-Urueta,Monzr M. Al Malki,Rizwan Romee,Scott D. Solomon,Auayporn Nademanee,Stacey Brown,Michael Slade,R. Pérez,Gabriela Rondon,Stephan J. Forman,Richard E. Champlin,Partow Kebriaei,Stefan O. Ciurea +16 more
TL;DR: It is suggested that haploidentical transplants performed with PTCy-based GVHD prophylaxis provide a very suitable alternative to HLA-matched transplantations for patients with ALL.
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Incidence and natural history of pure red cell aplasia in major ABO-mismatched haematopoietic cell transplantation
Fleur M. Aung,Benjamin Lichtiger,Roland L. Bassett,Ping Liu,Amin M. Alousi,Qaiser Bashier,Stefan O. Ciurea,Marcos de Lima,Chitra Hosing,Partow Kebriaei,Yago Nieto,Betul Oran,Simrit Parmar,Muzaffar H. Qazilbash,Nina Shah,Issa F. Khouri,Richard E. Champlin,Uday R. Popat +17 more
TL;DR: After major ABO‐mismatched HSCT, the incidence of PRCA was 7·5% and it resolved spontaneously or after withdrawal of immunosuppression in the majority of patients, suggesting that the only risk factor associated withPRCA was the use of a fludarabine/busulfan conditioning regimen.
Journal ArticleDOI
CD8+ cell depletion of donor lymphocyte infusions using cd8 monoclonal antibody-coated high-density microparticles (CD8-HDM) after allogeneic hematopoietic stem cell transplantation: a pilot study.
Edwin P. Alyea,Christine Canning,Donna Neuberg,Heather Daley,H. Houde,Sergio Giralt,Richard E. Champlin,Kerry Atkinson,Robert J. Soiffer +8 more
TL;DR: TheCD8-HDM Cell Separation System appears to be highly selective and effective in depleting CD8+ T cells from DLI apheresis products, and CD8-depleted DLI is capable of mediating a graft-versus-leukemia effect while minimizing GVHD.