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Richard E. Champlin
Researcher at University of Texas MD Anderson Cancer Center
Publications - 1500
Citations - 73470
Richard E. Champlin is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 138, co-authored 1402 publications receiving 66917 citations.
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Journal ArticleDOI
Selective depletion of CD8+ cells for prevention of graft-versus-host disease after bone marrow transplantation: A randomized controlled trial
Stephen D. Nimer,Janis V. Giorgi,James Gajewski,Nora Ku,Gary J. Schiller,Kyoung Lee,Mary C. Territo,Winston G. Ho,Stephen A. Feig,Michael T. Selch,Valentin Isacescu,Thomas A. Reichert,Richard E. Champlin +12 more
TL;DR: It is indicated that selective depletion of CD8+ cells from the bone marrow significantly reduces the incidence and severity of acute GVHD.
Journal ArticleDOI
Respiratory syncytial virus upper respiratory tract illnesses in adult blood and marrow transplant recipients: combination therapy with aerosolized ribavirin and intravenous immunoglobulin
S. Ghosh,Richard E. Champlin,Janet A. Englund,Sergio Giralt,Kenneth V. I. Rolston,I. Raad,K. Jacobson,Joyce Neumann,Cindy Ippoliti,S. Mallik,Estella Whimbey +10 more
TL;DR: In this article, the authors performed a pilot trial of therapy of RSV upper respiratory illnesses using aerosolized ribavirin and IVIG (500 mg/kg every other day), with the goal of preventing progression to pneumonia and death.
Journal ArticleDOI
Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Farhad Ravandi,Susan O'Brien,Jorge E. Cortes,Deborah M. Thomas,Rebecca Garris,Stefan Faderl,Jan A. Burger,Michael Rytting,Alessandra Ferrajoli,William G. Wierda,Srdan Verstovsek,Richard E. Champlin,Partow Kebriaei,Deborah McCue,Xuelin Huang,Elias Jabbour,Guillermo Garcia-Manero,Zeev Estrov,Hagop M. Kantarjian +18 more
TL;DR: The long‐term efficacy of a combination of chemotherapy and dasatinib in patients with Philadelphia chromosome–positive (Ph+) acute lymphoblastic leukemia (ALL) is not well established.
Journal ArticleDOI
Leukemia relapse after allogeneic bone marrow transplantation: a review
TL;DR: The increasing use of human leukocyte antigen (HLA) nonidentical donors, and HLA-matched unrelated donors will assure the continued growth in the use of this therapeutic modality.
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Sirolimus in combination with tacrolimus and corticosteroids for the treatment of resistant chronic graft-versus-host disease.
Daniel R. Couriel,Rima M. Saliba,Maricer P. Escalon,Yvonne Hsu,S. Ghosh,Cindy Ippoliti,K. Hicks,M. Donato,Sergio Giralt,Issa F. Khouri,Chitra Hosing,M. de Lima,Borje S. Andersson,Joyce Neumann,Richard E. Champlin +14 more
TL;DR: A significantly better outcome was observed in patients with a platelet count ≥100 × 109/l, as well as in those with true chronic manifestations of GVHD compared to those with acute GV HD beyond day 100, and controlled trials comparing this approach with alternative strategies to determine which can best achieve the goal of GvHD‐free survival are warranted.