M
Marie Neergaard Harder
Researcher at University of Copenhagen
Publications - 18
Citations - 1594
Marie Neergaard Harder is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Type 2 diabetes & Genome-wide association study. The author has an hindex of 15, co-authored 18 publications receiving 1434 citations. Previous affiliations of Marie Neergaard Harder include Novo Nordisk Foundation.
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Journal ArticleDOI
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
Momoko Horikoshi,Hanieh Yaghootkar,Dennis O. Mook-Kanamori,Dennis O. Mook-Kanamori,Ulla Sovio,Ulla Sovio,H. Rob Taal,Branwen J. Hennig,Jonathan P. Bradfield,Beate St Pourcain,David M. Evans,Pimphen Charoen,Pimphen Charoen,Marika Kaakinen,Diana L. Cousminer,Terho Lehtimäki,Eskil Kreiner-Møller,Nicole M. Warrington,Mariona Bustamante,Bjarke Feenstra,Diane J. Berry,Elisabeth Thiering,Thiemo Pfab,Thiemo Pfab,Sheila J. Barton,Beverley M. Shields,Marjan Kerkhof,Elisabeth M. van Leeuwen,Anthony J. C. Fulford,Zoltán Kutalik,Zoltán Kutalik,Jing Hua Zhao,Marcel den Hoed,Anubha Mahajan,Virpi Lindi,Liang Kee Goh,Jouke-Jan Hottenga,Ying Wu,Olli T. Raitakari,Marie Neergaard Harder,Aline Meirhaeghe,Aline Meirhaeghe,Aline Meirhaeghe,Ioanna Ntalla,Rany M. Salem,Rany M. Salem,Karen A. Jameson,Kaixin Zhou,Dorota Monies,Vasiliki Lagou,Mirna Kirin,Jani Heikkinen,Linda S. Adair,Fowzan S. Alkuraya,Ali Al-Odaib,Philippe Amouyel,Philippe Amouyel,Philippe Amouyel,Ehm A. Andersson,Amanda J. Bennett,Alexandra I. F. Blakemore,Jessica L. Buxton,Jean Dallongeville,Jean Dallongeville,Jean Dallongeville,Shikta Das,Eco J. C. de Geus,Xavier Estivill,Claudia Flexeder,Philippe Froguel,Philippe Froguel,Philippe Froguel,Frank Geller,Keith M. Godfrey,Keith M. Godfrey,Frédéric Gottrand,Christopher J. Groves,Torben Hansen,Torben Hansen,Joel N. Hirschhorn,Joel N. Hirschhorn,Albert Hofman,Mads V. Hollegaard,David M. Hougaard,Elina Hyppönen,Hazel Inskip,Aaron Isaacs,Aaron Isaacs,Torben Jørgensen,Christina Kanaka-Gantenbein,John P. Kemp,Wieland Kiess,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Norman Klopp,Bridget A. Knight,Christopher W. Kuzawa,George McMahon,John P. Newnham,Harri Niinikoski,Ben A. Oostra,Louise Pedersen,Dirkje S. Postma,Susan M. Ring,Fernando Rivadeneira,Neil R. Robertson,Sylvain Sebert,Sylvain Sebert,Olli Simell,Torsten Slowinski,Carla M. T. Tiesler,Anke Tönjes,Allan Vaag,Allan Vaag,Jorma Viikari,Jacqueline M. Vink,Nadja Hawwa Vissing,Nicholas J. Wareham,Gonneke Willemsen,Daniel R. Witte,Haitao Zhang,Jianhua Zhao,James F. Wilson,Michael Stumvoll,Andrew M. Prentice,Brian F. Meyer,Ewan R. Pearson,Colin Boreham,Cyrus Cooper,Matthew W. Gillman,George Dedoussis,Luis A. Moreno,Oluf Pedersen,Oluf Pedersen,Oluf Pedersen,Maiju Saarinen,Karen L. Mohlke,Dorret I. Boomsma,Seang-Mei Saw,Seang-Mei Saw,Timo A. Lakka,Antje Körner,Ruth J. F. Loos,Ken K. Ong,Peter Vollenweider,Cornelia M. van Duijn,Gerard H. Koppelman,Andrew T. Hattersley,John W. Holloway,Berthold Hocher,Joachim Heinrich,Chris Power,Mads Melbye,Mònica Guxens,Craig E. Pennell,Klaus Bønnelykke,Hans Bisgaard,Johan G. Eriksson,Elisabeth Widen,Hakon Hakonarson,André G. Uitterlinden,Anneli Pouta,Anneli Pouta,Debbie A Lawlor,George Davey Smith,Timothy M. Frayling,Mark I. McCarthy,Mark I. McCarthy,Struan F.A. Grant,Vincent W. V. Jaddoe,Marjo-Riitta Järvelin,Nicholas J. Timpson,Inga Prokopenko,Rachel M. Freathy,Rachel M. Freathy +174 more
TL;DR: The number of loci associated at genome-wide significance to 7, accounting for a similar proportion of variance as maternal smoking, are extended and highlight genetic links between fetal growth and postnatal growth and metabolism.
Journal ArticleDOI
Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes
Valgerdur Steinthorsdottir,Gudmar Thorleifsson,Patrick Sulem,Hannes Helgason,Niels Grarup,Asgeir Sigurdsson,Hafdis T. Helgadottir,Hrefna Johannsdottir,Olafur Th Magnusson,Sigurjon A. Gudjonsson,Johanne Marie Justesen,Marie Neergaard Harder,Marit E. Jørgensen,Cramer Christensen,Ivan Brandslund,Annelli Sandbæk,Torsten Lauritzen,Henrik Vestergaard,Allan Linneberg,Torben Jørgensen,Torben Jørgensen,Torben Jørgensen,Torben Hansen,Maryam S. Daneshpour,Mohammad-Sadegh Fallah,Astradur B. Hreidarsson,Gunnar Sigurdsson,Fereidoun Azizi,Rafn Benediktsson,Gisli Masson,Agnar Helgason,Augustine Kong,Daniel F. Gudbjartsson,Oluf Pedersen,Unnur Thorsteinsdottir,Kari Stefansson +35 more
TL;DR: Through whole-genome sequencing of 2,630 Icelanders and imputation into 11,114 Icelandic cases and 267,140 controls followed by testing in Danish and Iranian samples, 4 previously unreported variants affecting risk of type 2 diabetes (T2D) are discovered.
Journal ArticleDOI
Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults
Mariaelisa Graff,Robert A. Scott,Anne E. Justice,Kristin L. Young,Mary F. Feitosa,Llilda Barata,Thomas W. Winkler,Audrey Y. Chu,Audrey Y. Chu,Anubha Mahajan,David Hadley,Luting Xue,Luting Xue,Tsegaselassie Workalemahu,Nancy L. Heard-Costa,Nancy L. Heard-Costa,Marcel den Hoed,Marcel den Hoed,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Qibin Qi,Julius S. Ngwa,Frida Renström,Frida Renström,Lydia Quaye,John D. Eicher,James E. Hayes,James E. Hayes,Marilyn C. Cornelis,Marilyn C. Cornelis,Marilyn C. Cornelis,Zoltán Kutalik,Zoltán Kutalik,Elise Lim,Jian'an Luan,Jennifer E. Huffman,Jennifer E. Huffman,Weihua Zhang,Weihua Zhang,Wei Zhao,Paula J. Griffin,Toomas Haller,Shafqat Ahmad,Pedro Marques-Vidal,Stephanie A. Bien,Loic Yengo,Alexander Teumer,Albert V. Smith,Meena Kumari,Marie Neergaard Harder,Johanne Marie Justesen,Marcus E. Kleber,Marcus E. Kleber,Mette Hollensted,Kurt Lohman,Natalia V. Rivera,John Whitfield,Jing Hua Zhao,Heather M. Stringham,Leo-Pekka Lyytikäinen,Charlotte Huppertz,Charlotte Huppertz,Gonneke Willemsen,Gonneke Willemsen,Wouter J. Peyrot,Ying Wu,Kati Kristiansson,Kati Kristiansson,Ayse Demirkan,Ayse Demirkan,Myriam Fornage,Maija Hassinen,Lawrence F. Bielak,Gemma Cadby,Toshiko Tanaka,Reedik Mägi,Peter J. van der Most,Anne U. Jackson,Jennifer L. Bragg-Gresham,Veronique Vitart,Jonathan Marten,Pau Navarro,Claire Bellis,Claire Bellis,Dorota Pasko,Åsa Johansson,Soren Snitker,Yu-Ching Cheng,Joel Eriksson,Unhee Lim,Mette Aadahl,Mette Aadahl,Linda S. Adair,Najaf Amin,Beverley Balkau,Juha Auvinen,Juha Auvinen,John Beilby,John Beilby,Richard N. Bergman,Sven Bergmann,Sven Bergmann,Alain G. Bertoni,John Blangero,Amélie Bonnefond,Lori L. Bonnycastle,Judith B. Borja,Soren Brage,Fabio Busonero,Steve Buyske,Harry Campbell,Peter S. Chines,Francis S. Collins,Tanguy Corre,Tanguy Corre,George Davey Smith,Graciela E. Delgado,Nicole Dueker,Marcus Dörr,Tapani Ebeling,Tapani Ebeling,Gudny Eiriksdottir,Tõnu Esko,Jessica D. Faul,Mao Fu,Kristine Færch,Christian Gieger,Sven Gläser,Jian Gong,Penny Gordon-Larsen,Harald Grallert,Tanja B. Grammer,Niels Grarup,Gerard van Grootheest,Kennet Harald,Nicholas D. Hastie,Aki S. Havulinna,Dena G. Hernandez,Lucia A. Hindorff,Lynne J. Hocking,Lynne J. Hocking,Oddgeir L. Holmens,Christina Holzapfel,Jouke-Jan Hottenga,Jie Huang,Tao Huang,Jennie Hui,Jennie Hui,Cornelia Huth,Nina Hutri-Kähönen,Alan James,Alan James,John-Olov Jansson,Min A. Jhun,Markus Juonala,Markus Juonala,Leena Kinnunen,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Ivana Kolcic,Pirjo Komulainen,Johanna Kuusisto,Kirsti Kvaløy,Mika Kähönen,Timo A. Lakka,Lenore J. Launer,Benjamin Lehne,Cecilia M. Lindgren,Cecilia M. Lindgren,Cecilia M. Lindgren,Mattias Lorentzon,Mattias Lorentzon,Robert Luben,Michel Marre,Yuri Milaneschi,Keri L. Monda,Keri L. Monda,Grant W. Montgomery,Marleen H.M. de Moor,Marleen H.M. de Moor,Antonella Mulas,Martina Müller-Nurasyid,Arthur W. Musk,Arthur W. Musk,Reija Männikkö,Satu Männistö,Narisu Narisu,Matthias Nauck,Jennifer A. Nettleton,Ilja M. Nolte,Albertine J. Oldehinkel,Matthias Olden,Ken K. Ong,Sandosh Padmanabhan,Sandosh Padmanabhan,Lavinia Paternoster,Jeremiah Perez,Markus Perola,Markus Perola,Markus Perola,Annette Peters,Ulrike Peters,Patricia A. Peyser,Inga Prokopenko,Hannu Puolijoki,Olli T. Raitakari,Olli T. Raitakari,Tuomo Rankinen,Laura J. Rasmussen-Torvik,Rajesh Rawal,Paul M. Ridker,Paul M. Ridker,Lynda M. Rose,Igor Rudan,Cinzia Sarti,Mark A. Sarzynski,Kai Savonen,William R. Scott,Serena Sanna,Alan R. Shuldiner,Steve Sidney,Günther Silbernagel,Blair H. Smith,Blair H. Smith,Jennifer A. Smith,Harold Snieder,Alena Stančáková,Barbara Sternfeld,Amy J. Swift,Tuija Tammelin,Sian-Tsung Tan,Barbara Thorand,Dorothée Thuillier,Liesbeth Vandenput,Henrik Vestergaard,Henrik Vestergaard,Jana V. van Vliet-Ostaptchouk,Marie-Claude Vohl,Uwe Völker,Gérard Waeber,Mark Walker,Sarah H. Wild,Andrew Wong,Alan F. Wright,M. Carola Zillikens,Niha Zubair,Christopher A. Haiman,Loic LeMarchand,Ulf Gyllensten,Claes Ohlsson,Albert Hofman,Albert Hofman,Fernando Rivadeneira,Fernando Rivadeneira,André G. Uitterlinden,Louis Pérusse,James F. Wilson,Caroline Hayward,Ozren Polasek,Francesco Cucca,Kristian Hveem,Catharina A. Hartman,Anke Tönjes,Stefania Bandinelli,Lyle J. Palmer,Sharon L.R. Kardia,Rainer Rauramaa,Thorkild I. A. Sørensen,Jaakko Tuomilehto,Jaakko Tuomilehto,Jaakko Tuomilehto,Veikko Salomaa,Brenda W.J.H. Penninx,Eco J. C. de Geus,Eco J. C. de Geus,Dorret I. Boomsma,Terho Lehtimäki,Massimo Mangino,Massimo Mangino,Markku Laakso,Claude Bouchard,Nicholas G. Martin,Diana Kuh,Yongmei Liu,Allan Linneberg,Allan Linneberg,Winfried März,Winfried März,Winfried März,Konstantin Strauch,Mika Kivimäki,Tamara B. Harris,Vilmundur Gudnason,Henry Völzke,Lu Qi,Marjo-Riitta Järvelin,John C. Chambers,John C. Chambers,John C. Chambers,Jaspal S. Kooner,Jaspal S. Kooner,Jaspal S. Kooner,Philippe Froguel,Philippe Froguel,Charles Kooperberg,Peter Vollenweider,Göran Hallmans,Torben Hansen,Oluf Pedersen,Andres Metspalu,Nicholas J. Wareham,Claudia Langenberg,David R. Weir,David J. Porteous,Eric Boerwinkle,Daniel I. Chasman,Daniel I. Chasman,Daniel I. Chasman,Gonçalo R. Abecasis,Inês Barroso,Inês Barroso,Mark I. McCarthy,Mark I. McCarthy,Timothy M. Frayling,Jeffrey R. O'Connell,Cornelia M. van Duijn,Cornelia M. van Duijn,Michael Boehnke,Iris M. Heid,Karen L. Mohlke,David P. Strachan,Caroline S. Fox,Ching-Ti Liu,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Robert J. Klein,Andrew D. Johnson,Ingrid B. Borecki,Paul W. Franks,Paul W. Franks,Paul W. Franks,Kari E. North,L. Adrienne Cupples,L. Adrienne Cupples,Ruth J. F. Loos,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen +349 more
TL;DR: In additional genome-wide meta-analyses adjusting for PA and interaction with PA, 11 novel adiposity loci are identified, suggesting that accounting for PA or other environmental factors that contribute to variation in adiposity may facilitate gene discovery.
Journal ArticleDOI
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Anne E. Justice,Thomas W. Winkler,Mary F. Feitosa,Misa Graff,Virginia Fisher,Kristin L. Young,Llilda Barata,Xuan Deng,Jacek Czajkowski,David Hadley,Julius S. Ngwa,Julius S. Ngwa,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Audrey Y. Chu,Audrey Y. Chu,Nancy L. Heard-Costa,Nancy L. Heard-Costa,Elise Lim,Jeremiah Perez,John D. Eicher,Zoltán Kutalik,Luting Xue,Anubha Mahajan,Frida Renström,Frida Renström,Joseph M. Wu,Qibin Qi,Shafqat Ahmad,Shafqat Ahmad,Tamuno Alfred,Najaf Amin,Lawrence F. Bielak,Amélie Bonnefond,Jennifer Bragg,Gemma Cadby,Martina Chittani,Scott Coggeshall,Tanguy Corre,Nese Direk,Nese Direk,Joel Eriksson,Krista Fischer,Mathias Gorski,Marie Neergaard Harder,Momoko Horikoshi,Tao Huang,Tao Huang,Jennifer E. Huffman,Jennifer E. Huffman,Anne U. Jackson,Johanne Marie Justesen,Stavroula Kanoni,Leena Kinnunen,Marcus E. Kleber,Pirjo Komulainen,Meena Kumari,Meena Kumari,Unhee Lim,Jian'an Luan,Leo-Pekka Lyytikäinen,Massimo Mangino,Massimo Mangino,Ani Manichaikul,Jonathan Marten,Rita P. S. Middelberg,Martina Müller-Nurasyid,Pau Navarro,Louis Pérusse,Natalia Pervjakova,Cinzia Sarti,Albert V. Smith,Jennifer A. Smith,Alena Stančáková,Rona J. Strawbridge,Heather M. Stringham,Yun Ju Sung,Toshiko Tanaka,Alexander Teumer,Stella Trompet,Sander W. van der Laan,Peter J. van der Most,Jana V. van Vliet-Ostaptchouk,Sailaja Vedantam,Sailaja Vedantam,Niek Verweij,Jacqueline M. Vink,Jacqueline M. Vink,Veronique Vitart,Ying Wu,Loic Yengo,Weihua Zhang,Weihua Zhang,Jing Hua Zhao,Martina E. Zimmermann,Niha Zubair,Gonçalo R. Abecasis,Linda S. Adair,Saima Afaq,Saima Afaq,Uzma Afzal,Uzma Afzal,Stephan J. L. Bakker,Traci M. Bartz,John Beilby,John Beilby,Richard N. Bergman,Sven Bergmann,Reiner Biffar,John Blangero,Eric Boerwinkle,Lori L. Bonnycastle,Erwin P. Bottinger,Daniele Braga,Brendan M. Buckley,Steve Buyske,Harry Campbell,John C. Chambers,John C. Chambers,Francis S. Collins,Joanne E. Curran,Gert J. de Borst,Anton J. M. de Craen,Eco J. C. de Geus,George Dedoussis,Graciela E. Delgado,Hester M. den Ruijter,Gudny Eiriksdottir,Anna Eriksson,Tõnu Esko,Tõnu Esko,Tõnu Esko,Jessica D. Faul,Ian Ford,Terrence Forrester,Karl Gertow,Bruna Gigante,Nicola Glorioso,Jian Gong,Harald Grallert,Tanja B. Grammer,Niels Grarup,Saskia Haitjema,Göran Hallmans,Anders Hamsten,Torben Hansen,Tamara B. Harris,Catharina A. Hartman,Maija Hassinen,Nicholas D. Hastie,Andrew C. Heath,Dena G. Hernandez,Lucia A. Hindorff,Lynne J. Hocking,Lynne J. Hocking,Mette Hollensted,Oddgeir L. Holmen,Georg Homuth,Jouke-Jan Hottenga,Jie Huang,Joseph Hung,Joseph Hung,Nina Hutri-Kähönen,Erik Ingelsson,Erik Ingelsson,Alan James,Alan James,John-Olov Jansson,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Min A. Jhun,Marit E. Jørgensen,Markus Juonala,Mika Kähönen,Magnus Karlsson,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Ivana Kolcic,Genovefa Kolovou,Charles Kooperberg,Bernhard K. Krämer,Johanna Kuusisto,Kirsti Kvaløy,Timo A. Lakka,Claudia Langenberg,Lenore J. Launer,Karin Leander,Nanette R. Lee,Lars Lind,Cecilia M. Lindgren,Allan Linneberg,Stéphane Lobbens,Marie Loh,Marie Loh,Mattias Lorentzon,Robert Luben,Gitta H. Lubke,Anja Ludolph-Donislawski,Sara Lupoli,Pamela A. F. Madden,Reija Männikkö,Pedro Marques-Vidal,Nicholas G. Martin,Colin A. McKenzie,Barbara McKnight,Barbara McKnight,Dan Mellström,Cristina Menni,Grant W. Montgomery,Arthur W. Musk,Arthur W. Musk,Narisu Narisu,Matthias Nauck,Ilja M. Nolte,Albertine J. Oldehinkel,Matthias Olden,Ken K. Ong,Sandosh Padmanabhan,Sandosh Padmanabhan,Patricia A. Peyser,Charlotta Pisinger,David J. Porteous,Olli T. Raitakari,Tuomo Rankinen,Dabeeru C. Rao,Laura J. Rasmussen-Torvik,Rajesh Rawal,Treva Rice,Paul M. Ridker,Lynda M. Rose,Stephanie A. Bien,Igor Rudan,Serena Sanna,Mark A. Sarzynski,Naveed Sattar,Kai Savonen,David Schlessinger,Salome Scholtens,Claudia Schurmann,Robert A. Scott,Bengt Sennblad,Marten A. Siemelink,Günther Silbernagel,P. Eline Slagboom,Harold Snieder,Jan A. Staessen,Jan A. Staessen,David J. Stott,Morris A. Swertz,Amy J. Swift,Kent D. Taylor,Bamidele O. Tayo,Barbara Thorand,Dorothée Thuillier,Jaakko Tuomilehto,André G. Uitterlinden,Liesbeth Vandenput,Marie-Claude Vohl,Henry Völzke,Judith M. Vonk,Gérard Waeber,Melanie Waldenberger,Rudi G. J. Westendorp,Sarah H. Wild,Gonneke Willemsen,Bruce H. R. Wolffenbuttel,Andrew Wong,Alan F. Wright,Wei Zhao,M. Carola Zillikens,Damiano Baldassarre,Beverley Balkau,Stefania Bandinelli,Carsten A. Böger,Dorret I. Boomsma,Claude Bouchard,Marcel Bruinenberg,Daniel I. Chasman,Yii-Der Ida Chen,Peter S. Chines,Richard S. Cooper,Francesco Cucca,Daniele Cusi,Ulf de Faire,Luigi Ferrucci,Paul W. Franks,Paul W. Franks,Paul W. Franks,Philippe Froguel,Penny Gordon-Larsen,Hans J. Grabe,Hans J. Grabe,Vilmundur Gudnason,Christopher A. Haiman,Caroline Hayward,Kristian Hveem,Andrew D. Johnson,J. Wouter Jukema,Sharon L.R. Kardia,Mika Kivimäki,Jaspal S. Kooner,Jaspal S. Kooner,Diana Kuh,Markku Laakso,Terho Lehtimäki,Loic Le Marchand,Winfried März,Winfried März,Mark I. McCarthy,Mark I. McCarthy,Andres Metspalu,Andrew P. Morris,Andrew P. Morris,Claes Ohlsson,Lyle J. Palmer,Gerard Pasterkamp,Oluf Pedersen,Annette Peters,Ulrike Peters,Ozren Polasek,Ozren Polasek,Bruce M. Psaty,Bruce M. Psaty,Lu Qi,Lu Qi,Rainer Rauramaa,Blair H. Smith,Blair H. Smith,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Konstantin Strauch,Henning Tiemeier,Elena Tremoli,Pim van der Harst,Henrik Vestergaard,Henrik Vestergaard,Peter Vollenweider,Nicholas J. Wareham,David R. Weir,John Whitfield,James F. Wilson,Jessica Tyrrell,Timothy M. Frayling,Inês Barroso,Inês Barroso,Michael Boehnke,Panagiotis Deloukas,Panagiotis Deloukas,Panagiotis Deloukas,Caroline S. Fox,Joel N. Hirschhorn,Joel N. Hirschhorn,David J. Hunter,David J. Hunter,Tim D. Spector,David P. Strachan,Cornelia M. van Duijn,Iris M. Heid,Karen L. Mohlke,Jonathan Marchini,Ruth J. F. Loos,Ruth J. F. Loos,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Ching-Ti Liu,Ingrid B. Borecki,Kari E. North,L. Adrienne Cupples,L. Adrienne Cupples +370 more
TL;DR: The results suggest that tobacco smoking may alter the genetic susceptibility to overall adiposity and body fat distribution, and highlight the importance of accounting for environment in genetic analyses.
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Anne E. Justice,Thomas W. Winkler,Mary F. Feitosa,Misa Graff,Virginia Fisher,Kristin L. Young,Llilda Barata,Xuan Deng,Jacek Czajkowski,David Hadley,Julius S. Ngwa,Tarunveer S. Ahluwalia,Audrey Y. Chu,Nancy L. Heard-Costa,Elise Lim,Jeremiah Perez,John D. Eicher,Zoltán Kutalik,Luting Xue,Anubha Mahajan,Frida Renström,Joseph M. Wu,Qibin Qi,Shafqat Ahmad,Tamuno Alfred,Najaf Amin,Lawrence F. Bielak,Amélie Bonnefond,Jennifer Bragg,Gemma Cadby,Martina Chittani,Scott Coggeshall,Tanguy Corre,Nese Direk,Joel Eriksson,Krista Fischer,Mathias Gorski,Marie Neergaard Harder,Momoko Horikoshi,Tao Huang,Jennifer E. Huffman,Anne U. Jackson,Johanne Marie Justesen,Stavroula Kanoni,Leena Kinnunen,Marcus E. Kleber,Pirjo Komulainen,Meena Kumari,Unhee Lim,Jian'an Luan,Leo-Pekka Lyytikäinen,Massimo Mangino,Ani Manichaikul,Jonathan Marten,Rita P. S. Middelberg,Martina Mueller-Nurasyid,Pau Navarro,Louis Pérusse,Natalia Pervjakova,Cinzia Sarti,Albert V. Smith,Jennifer A. Smith,Alena Stančáková,Rona J. Strawbridge,Heather M. Stringham,Yun Ju Sung,Toshiko Tanaka,Alexander Teumer,Stella Trompet,Sander W. van der Laan,Peter J. van der Most,Jana V. van Vliet-Ostaptchouk,Sailaja Vedantam,Niek Verweij,Jacqueline M. Vink,Veronique Vitart,Ying Wu,Loic Yengo,Weihua Zhang,Jing Hua Zhao,Martina E. Zimmermann,Niha Zubair,Gonçalo R. Abecasis,Linda S. Adair,Saima Afaq,Uzma Afzal,Stephan J. L. Bakker,Traci M. Bartz,John Beilby,Richard N. Bergman,Sven Bergmann,Reiner Biffar,John Blangero,Eric Boerwinkle,Lori L. Bonnycastle,Erwin P. Bottinger,Daniele Braga,Brendan M. Buckley,Steve Buyske,Harry Campbell,John C. Chambers,Francis S. Collins,Joanne E. Curran,Gert J. de Borst,Anton J. M. de Craen,Eco J. C. de Geus,George Dedoussis,Graciela E. Delgado,Hester M. den Ruijter,Gudny Eiriksdottir,Anna Eriksson,Tõnu Esko,Jessica D. Faul,Ian Ford,Terrence Forrester,Karl Gertow,Bruna Gigante,Nicola Glorioso,Jian Gong,Harald Grallert,Tanja B. Grammer,Niels Grarup,Saskia Haitjema,Göran Hallmans,Anders Hamsten,Torben Hansen,Tamara B. Harris,Catharina A. Hartman,Maija Hassinen,Nicholas D. Hastie,Andrew Heath,Dena G. Hernandez,Lucia A. Hindorff,Lynne J. Hocking,Mette Hollensted,Oddgeir L. Holmen,Georg Homuth,Jouke-Jan Hottenga,Jie Huang,Joseph Hung,Nina Hutri-Kähönen,Erik Ingelsson,Alan James,John-Olov Jansson,Marjo-Riitta Järvelin,Min A. Jhun,Marit E. Jørgensen,Markus Juonala,Mika Kähönen,Magnus Karlsson,Heikki A. Koistinen,Ivana Kolcic,Genovefa Kolovou,Charles Kooperberg,Bernhard K. Krämer,Johanna Kuusisto,Kirsti Kvaløy,Timo A. Lakka,Claudia Langenberg,Lenore J. Launer,Karin Leander,Nanette R. Lee,Lars Lind,Cecilia M. Lindgren,Allan Linneberg,Stéphane Lobbens,Marie Loh,Mattias Lorentzon,Robert Luben,Gitta H. Lubke,Anja Ludolph-Donislawski,Sara Lupoli,Pamela A. F. Madden,Reija Männikkö,Pedro Marques-Vidal,Nicholas G. Martin,Colin A. McKenzie,Barbara McKnight,Dan Mellström,Cristina Menni,Grant W. Montgomery,Arthur W. Musk,Narisu Narisu,Matthias Nauck,Ilja M. Nolte,Albertine J. Oldehinkel,Matthias Olden,Ken K. Ong,Sandosh Padmanabhan,Patricia A. Peyser,Charlotta Pisinger,David J. Porteous,Olli T. Raitakari,Tuomo Rankinen,Dabeeru C. Rao,Laura J. Rasmussen-Torvik,Rajesh Rawal,Treva Rice,Paul M. Ridker,Lynda M. Rose,Stephanie A. Bien,Igor Rudan,Serena Sanna,Mark A. Sarzynski,Naveed Sattar,Kai Savonen,David Schlessinger,Salome Scholtens,Claudia Schurmann,Robert A. Scott,Bengt Sennblad,Marten A. Siemelink,Günther Silbernagel,P. Eline Slagboom,Harold Snieder,Jan A. Staessen,David J. Stott,Morris A. Swertz,Amy J. Swift,Kent D. Taylor,Bamidele O. Tayo,Barbara Thorand,Dorothée Thuillier,Jaakko Tuomilehto,André G. Uitterlinden,Liesbeth Vandenput,Marie-Claude Vohl,Henry Völzke,Judith M. Vonk,Gérard Waeber,Melanie Waldenberger,Rudi G. J. Westendorp,Sarah H. Wild,Gonneke Willemsen,Bruce H. R. Wolffenbuttel,Andrew Wong,Alan F. Wright,Wei Zhao,M. Carola Zillikens,Damiano Baldassarre,Beverley Balkau,Stefania Bandinelli,Carsten A. Böger,Dorret I. Boomsma,Claude Bouchard,Marcel Bruinenberg,Daniel I. Chasman,Yii-Der Ida Chen,Peter S. Chines,Richard S. Cooper,Francesco Cucca,Daniele Cusi,Ulf de Faire,Luigi Ferrucci,Paul W. Franks,Philippe Froguel,Penny Gordon-Larsen,Hans-Jörgen Grabe,Vilmundur Gudnason,Christopher A. Haiman,Caroline Hayward,Kristian Hveem,Andrew D. Johnson,Wouter Jukema,Sharon L.R. Kardia,Mika Kivimäki,Jaspal S. Kooner,Diana Kuh,Markku Laakso,Terho Lehtimäki,Loic Le Marchand,Winfried März,Mark I. McCarthy,Andres Metspalu,Andrew P. Morris,Claes Ohlsson,Lyle J. Palmer,Gerard Pasterkamp,Oluf Pedersen,Annette Peters,Ulrike Peters,Ozren Polasek,Bruce M. Psaty,Lu Qi,Rainer Rauramaa,Blair H. Smith,Thorkild I. A. Sørensen,Konstantin Strauch,Henning Tiemeier,Elena Tremoli,Pim van der Harst,Henrik Vestergaard,Peter Vollenweider,Nicholas J. Wareham,David R. Weir,John Whitfield,James F. Wilson,Jessica Tyrrell,Timothy M. Frayling,Inês Barroso,Michael Boehnke,Panagiotis Deloukas,Caroline S. Fox,Joel N. Hirschhorn,David J. Hunter,Tim D. Spector,David P. Strachan,Cornelia M. van Duijn,Iris M. Heid,Karen L. Mohlke,Jonathan Marchini,Ruth J. F. Loos,Tuomas O. Kilpeläinen,Ching-Ti Liu,Ingrid B. Borecki,Kari E. North,L. Adrienne Cupples +316 more
TL;DR: In this paper, the authors used GWAS data from 51,080 current smokers and 190,178 nonsmokers (87% European descent) to identify loci influencing BMI and central adiposity, measured as waist circumference and waist-to-hip ratio both adjusted for BMI.