Rong Wang

TL;DR: It is demonstrated that tanshinol has protective effect on CCl4-induced liver fibrosis via inhibiting oxidative stress and inflammation, which may be associated with the regulation of nuclear factor erythroid2-related factor 2/hemeoxygenase-a and nuclear factor kappa B/inhibitor of kappa A alpha signaling pathways.

TL;DR: The physical origin of the shape resonance effect of second-harmonic generation from periodic arrays of subwavelength rectangular air hole with various aspect ratios perforated in gold thin films is clarified and a nonlinear coupled-mode theory is set up to solve energy conversion within the nanoscale air hole.

TL;DR: In this article, a polyamide thin film layer was synthesized via interfacial polymerization, by circulating the reactant monomers including polyethyleneimine (PEI), piperazine (PIP) and trimesoyl chloride (TMC) through the hollow fibre lumen.

TL;DR: In this article, a pH-responsive co-delivery platform was developed for metformin (Met), a known immuno-metabolic modulator, and short interfering RNA (siRNA) targeting fibrinogen-like protein 1 mRNA (siFGL1), using a hybrid biomimetic membrane (from macrophages and cancer cells)-camouflaged poly (lactic-co-glycolic acid) nanoparticles.

TL;DR: The method affords a series of 2-CF3-2-indole-substituted thiochromanes featuring a CF3-containing quaternary stereocenter in excellent yields, diastereoselectivity, and enantioselectivities.