R
Ruth Steward
Researcher at Rutgers University
Publications - 75
Citations - 7324
Ruth Steward is an academic researcher from Rutgers University. The author has contributed to research in topics: Drosophila Protein & Gene. The author has an hindex of 38, co-authored 72 publications receiving 6944 citations. Previous affiliations of Ruth Steward include University of Virginia & Princeton University.
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Journal ArticleDOI
Methylation as a Crucial Step in Plant microRNA Biogenesis
Bin Yu,Zhiyong Yang,Junjie Li,Svetlana Minakhina,Maocheng Yang,Richard W. Padgett,Ruth Steward,Xuemei Chen +7 more
TL;DR: It is shown that plant microRNAs (miRNAs) have a naturally occurring methyl group on the ribose of the last nucleotide, a new and crucial step in plant miRNA biogenesis and have profound implications in the function of miRNAs.
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PR-Set7 Is a Nucleosome-Specific Methyltransferase that Modifies Lysine 20 of Histone H4 and Is Associated with Silent Chromatin
Kenichi Nishioka,Judd C. Rice,Kavitha Sarma,Hediye Erdjument-Bromage,Janis Werner,Yanming Wang,Sergei Chuikov,Pablo Valenzuela,Paul Tempst,Ruth Steward,John T. Lis,C. David Allis,Danny Reinberg +12 more
TL;DR: The hypothesis that methylation of H4 lysine 20 maintains silent chromatin, in part, by precluding neighboring acetylation on the H4 tail is supported.
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Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel
TL;DR: The Drosophila gene, dorsal, is a maternal effect locus that is essential for the establishment of dorsal-ventral polarity in the developing embryo.
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Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function
TL;DR: It is suggested that nuclear localization is critical for dorsal to function as a morphogen and that the distribution of the dorsal protein determines cell fate along the dorsal-ventral axis.
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Transcriptome-wide distribution and function of RNA hydroxymethylcytosine
Benjamin Delatte,Fei Wang,Long Vo Ngoc,Evelyne Collignon,Elise Bonvin,Rachel Deplus,Emilie Calonne,Bouchra Hassabi,Pascale Putmans,Stephan Awe,Collin Wetzel,Judith Kreher,Romuald Soin,Catherine Creppe,Patrick A. Limbach,Cyril Gueydan,Véronique Kruys,Alexander Brehm,Svetlana Minakhina,Matthieu Defrance,Ruth Steward,François Fuks +21 more
TL;DR: It is found that RNA hydroxymethylation can favor mRNA translation and is found to be most abundant in the Drosophila brain, and Tet-deficient fruitflies suffer impaired brain development, accompanied by decreased RNA hydroxyethylation.