S
Scott C. Weaver
Researcher at University of Texas Medical Branch
Publications - 584
Citations - 40298
Scott C. Weaver is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Virus & Alphavirus. The author has an hindex of 92, co-authored 536 publications receiving 32230 citations. Previous affiliations of Scott C. Weaver include Mount Sinai St. Luke's and Mount Sinai Roosevelt & Lenox Hill Hospital.
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Zika Virus Vector Competency of Mosquitoes, Gulf Coast, United States
Charles E. Hart,Christopher M. Roundy,Sasha R. Azar,Jing H. Huang,Ruimei Yun,Erin S. Reynolds,Grace Leal,Martin Reyna Nava,Jeremy Vela,Pamela M. Stark,Mustapha Debboun,Shannan L. Rossi,Nikos Vasilakis,Saravanan Thangamani,Scott C. Weaver +14 more
TL;DR: This work tested Cx.
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Extended Preclinical Safety, Efficacy and Stability Testing of a Live-attenuated Chikungunya Vaccine Candidate
TL;DR: Compared to wild-type CHIK virus, both vaccines generated lower viral loads in a wide variety of tissues and organs, including the brain and leg muscle, but CHIKV/IRES exhibited marked restrictions in dissemination and viral loads compared to 181/clone25, and was never found outside the blood, spleen and muscle.
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Electron Microscopic Analysis of Infection Patterns for Venezuelan Equine Encephalomyelitis Virus in the Vector Mosquito, Culex (Melanoconion) Taeniopus
TL;DR: The results suggest that virus particles penetrate the mesenteron and accumulate in the abdominal fat body prior to replication within the vector, which differs from that reported for other arbovirus-vector pairs.
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Venezuelan Equine Encephalomyelitis Virus Structure and Its Divergence from Old World Alphaviruses
TL;DR: The 25-Åstructure of VEE virus, obtained from electron cryomicroscopy and image reconstruction, has a T=4 icosahedral arrangement, similar to that observed in Old World Sindbis, Semliki Forest, and Ross River alphaviruses.
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A Five-Amino-Acid Deletion of the Eastern Equine Encephalitis Virus Capsid Protein Attenuates Replication in Mammalian Systems but Not in Mosquito Cells
TL;DR: It is identified that amino acids 55 to 75, within the N terminus of the capsid, is critical for the inhibition of host cell gene expression and to the protection of EEEV from the antiviral effects of IFNs.