S
Scott C. Weaver
Researcher at University of Texas Medical Branch
Publications - 584
Citations - 40298
Scott C. Weaver is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Virus & Alphavirus. The author has an hindex of 92, co-authored 536 publications receiving 32230 citations. Previous affiliations of Scott C. Weaver include Mount Sinai St. Luke's and Mount Sinai Roosevelt & Lenox Hill Hospital.
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Journal ArticleDOI
Equine amplification and virulence of subtype IE Venezuelan equine encephalitis viruses isolated during the 1993 and 1996 Mexican epizootics.
Dante Gonzalez-Salazar,Jose G. Estrada-Franco,Anne Sophie Carrara,Judith F. Aronson,Scott C. Weaver +4 more
TL;DR: The duration and scope of the recent Mexican epizootics were limited by lack of equine amplification characteristic of previous, more extensive VEE outbreaks, which may have resulted from the circulation of a more equine-neurotropic, subtype IE virus strain or from increased transmission to horses due to amplification by other vertebrate hosts or transmission by more competent mosquito vectors.
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Vector competence of Aedes aegypti and Aedes vittatus (Diptera: Culicidae) from Senegal and Cape Verde archipelago for West African lineages of chikungunya virus.
Cheikh Tidiane Diagne,Oumar Faye,Mathilde Guerbois,Rachel Knight,Diawo Diallo,Ousmane Faye,Yamar Ba,Ibrahima Dia,Scott C. Weaver,Amadou A. Sall,Mawlouth Diallo +10 more
TL;DR: In this paper, vector competence of wild-type, urban, and non-urban Aedes aegypti and Ae. vittatus from Senegal and Cape Verde for chikungunya virus (CHIKV) was investigated.
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IRES-Containing VEEV Vaccine Protects Cynomolgus Macaques from IE Venezuelan Equine Encephalitis Virus Aerosol Challenge
Shannan L. Rossi,Kasi E. Russell-Lodrigue,Stephanie Z. Killeen,Eryu Wang,Grace Leal,Nicholas A. Bergren,Heather Vinet-Oliphant,Scott C. Weaver,Chad J. Roy +8 more
TL;DR: It is demonstrated that the IRES-based VEEV vaccine’s ability to protect against febrile disease in cynomolgus macaques was well tolerated and elicited robust neutralizing antibody titers noticed as early as day 14.
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Effects of Chikungunya virus immunity on Mayaro virus disease and epidemic potential.
Emily M. Webb,Sasha R. Azar,Sherry L. Haller,Rose M. Langsjoen,Candace E. Cuthbert,Anushka T. Ramjag,Huanle Luo,Kenneth S. Plante,Tian Wang,Graham Simmons,Christine V.F. Carrington,Scott C. Weaver,Shannan L. Rossi,Albert J. Auguste,Albert J. Auguste +14 more
TL;DR: It is suggested that CHIKV infection can confer cross-protective effects against MAYV, and the resultant reduction in viremia may limit the emergence potential of MAYV.
Posted ContentDOI
Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility
Pei Yong Shi,Jessica A. Plante,Yang Liu,Jianying Liu,Hongjie Xia,Bryan A. Johnson,Kumari G. Lokugamage,Xianwen Zhang,Antonio E. Muruato,Jing Zou,Camila R. Fontes-Garfias,Divya Mirchandani,Dionna Scharton,Birte Kalveram,John P. Bilello,Zhiqiang Ku,Zhiqiang An,Alexander N. Freiberg,Vineet D. Menachery,Xuping Xie,Kenneth S. Plante,Scott C. Weaver +21 more
TL;DR: The hamster results confirm clinical evidence that the D614G mutation enhances viral loads in the upper respiratory tract of COVID-19 patients and may increases transmission and antibody neutralization, and suggest therapeutic antibodies should be tested against the circulating G614 virus before clinical development.