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Scott C. Weaver

Researcher at University of Texas Medical Branch

Publications -  584
Citations -  40298

Scott C. Weaver is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Virus & Alphavirus. The author has an hindex of 92, co-authored 536 publications receiving 32230 citations. Previous affiliations of Scott C. Weaver include Mount Sinai St. Luke's and Mount Sinai Roosevelt & Lenox Hill Hospital.

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Equine amplification and virulence of subtype IE Venezuelan equine encephalitis viruses isolated during the 1993 and 1996 Mexican epizootics.

TL;DR: The duration and scope of the recent Mexican epizootics were limited by lack of equine amplification characteristic of previous, more extensive VEE outbreaks, which may have resulted from the circulation of a more equine-neurotropic, subtype IE virus strain or from increased transmission to horses due to amplification by other vertebrate hosts or transmission by more competent mosquito vectors.
Journal ArticleDOI

IRES-Containing VEEV Vaccine Protects Cynomolgus Macaques from IE Venezuelan Equine Encephalitis Virus Aerosol Challenge

TL;DR: It is demonstrated that the IRES-based VEEV vaccine’s ability to protect against febrile disease in cynomolgus macaques was well tolerated and elicited robust neutralizing antibody titers noticed as early as day 14.
Posted ContentDOI

Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility

TL;DR: The hamster results confirm clinical evidence that the D614G mutation enhances viral loads in the upper respiratory tract of COVID-19 patients and may increases transmission and antibody neutralization, and suggest therapeutic antibodies should be tested against the circulating G614 virus before clinical development.