S
Scott C. Weaver
Researcher at University of Texas Medical Branch
Publications - 584
Citations - 40298
Scott C. Weaver is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Virus & Alphavirus. The author has an hindex of 92, co-authored 536 publications receiving 32230 citations. Previous affiliations of Scott C. Weaver include Mount Sinai St. Luke's and Mount Sinai Roosevelt & Lenox Hill Hospital.
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Journal ArticleDOI
Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States.
Jennifer L Harcourt,Jennifer L Harcourt,Azaibi Tamin,Xiaoyan Lu,Shifaq Kamili,Senthil Kumar K. Sakthivel,Janna Murray,Krista Queen,Ying Tao,Clinton R. Paden,Jing Zhang,Yan Li,Anna Uehara,Haibin Wang,Cynthia S. Goldsmith,Hannah A. Bullock,Lijuan Wang,Brett Whitaker,Brian Lynch,Rashi Gautam,Craig Schindewolf,Kumari G. Lokugamage,Dionna Scharton,Jessica A. Plante,Divya Mirchandani,Steven G. Widen,Krishna Narayanan,Shinji Makino,Thomas G. Ksiazek,Kenneth S. Plante,Scott C. Weaver,Stephen Lindstrom,Suxiang Tong,Suxiang Tong,Vineet D. Menachery,Vineet D. Menachery,Natalie J. Thornburg,Natalie J. Thornburg,Natalie J. Thornburg +38 more
TL;DR: It is found that the virus replicates to high titer in Vero-CCL81 cells and Vero E6 cells in the absence of trypsin, and it is hoped that open access to this reagent will expedite development of medical countermeasures.
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Neutralizing Activity of BNT162b2-Elicited Serum.
Yang Liu,Jianying Liu,Hongjie Xia,Xianwen Zhang,Camila R. Fontes-Garfias,Kena A. Swanson,Hui Cai,Ritu Sarkar,Wei Chen,Mark Cutler,David A. Cooper,Scott C. Weaver,Alexander Muik,Ugur Sahin,Kathrin U. Jansen,Xuping Xie,Philip R. Dormitzer,Pei Yong Shi +17 more
TL;DR: In this paper, the BNT162b2 vaccine was shown to neutralize the P.1.1, B.1., B.7, and B.135 lineages of SARS-CoV-2.
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Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.
Bryan A. Johnson,Xuping Xie,Adam L. Bailey,Birte Kalveram,Kumari G. Lokugamage,Antonio E. Muruato,Jing Zou,Xianwen Zhang,Terry L. Juelich,Jennifer K. Smith,Lihong Zhang,Nathen E. Bopp,Craig Schindewolf,Michelle N Vu,Abigail Vanderheiden,Emma S. Winkler,Daniele M. Swetnam,Jessica A. Plante,Patricia V. Aguilar,Kenneth S. Plante,Vsevolod L. Popov,Benhur Lee,Scott C. Weaver,Mehul S. Suthar,Andrew Routh,Ping Ren,Zhiqiang Ku,Zhiqiang An,Kari Debbink,Michael S. Diamond,Pei Yong Shi,Alexander N. Freiberg,Vineet D. Menachery +32 more
TL;DR: In this paper, a mutant SARS-CoV-2 that lacks the furin cleavage site (ΔPRRA) was generated, which had faster kinetics, improved fitness in Vero E6 cells and reduced spike protein processing.
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Characterization of a Novel Murine Model to Study Zika Virus
Shannan L. Rossi,Robert B. Tesh,Sasha R. Azar,Antonio E. Muruato,Kathryn A. Hanley,Albert J. Auguste,Rose M. Langsjoen,Slobodan Paessler,Nikos Vasilakis,Scott C. Weaver +9 more
TL;DR: Characterization of an Asian lineage ZIKV strain in a murine model, and one of the few studies reporting a model of Zika disease and demonstrating age-dependent morbidity and mortality, could provide a platform for testing the efficacy of antivirals and vaccines.
Journal ArticleDOI
Venezuelan equine encephalitis.
Scott C. Weaver,Cristina Ferro,Roberto Barrera,Roberto Barrera,Jorge Boshell,Juan Carlos Navarro +5 more
TL;DR: Although epizootic VEEV strains are opportunistic in their use of mosquito vectors, the most widespread outbreaks appear to involve specific adaptation to Ochlerotatus taeniorhynchus, themost common vector in many coastal areas.