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Scott C. Weaver

Researcher at University of Texas Medical Branch

Publications -  584
Citations -  40298

Scott C. Weaver is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Virus & Alphavirus. The author has an hindex of 92, co-authored 536 publications receiving 32230 citations. Previous affiliations of Scott C. Weaver include Mount Sinai St. Luke's and Mount Sinai Roosevelt & Lenox Hill Hospital.

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A recombinant virus vaccine that protects against both Chikungunya and Zika virus infections.

TL;DR: A single-dose, bivalent experimental vaccine based on a chimeric vesicular stomatitis virus that expresses the CHIKV envelope polyprotein in place of the VSV glycoprotein and also expresses the membrane-envelope (ME) glycoproteins of ZIKV could provide durable, low-cost protection against both chikungunya virus and Zika virus for people traveling to or living in areas where both viruses are circulating.
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Arthritogenic alphaviruses: epidemiological and clinical perspective on emerging arboviruses.

TL;DR: This Review highlights key features of alphaviruses that are known to cause arthritic disease in humans and outlines the present findings pertaining to classification, immunogenicity, pathogenesis, and experimental approaches aimed at limiting disease manifestations.
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IRES-Based Venezuelan Equine Encephalitis Vaccine Candidate Elicits Protective Immunity in Mice

TL;DR: This IRES-based vaccine was unable to establish productive infection in mosquito cell cultures or in intrathoracically injected Aedes taeniorhynchus, demonstrating that it cannot be transmitted from a vaccinee.