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Scott C. Weaver

Researcher at University of Texas Medical Branch

Publications -  584
Citations -  40298

Scott C. Weaver is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Virus & Alphavirus. The author has an hindex of 92, co-authored 536 publications receiving 32230 citations. Previous affiliations of Scott C. Weaver include Mount Sinai St. Luke's and Mount Sinai Roosevelt & Lenox Hill Hospital.

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A trans-complementation system for SARS-CoV-2 recapitulates authentic viral replication without virulence.

TL;DR: In this article, a trans-complementation system that produces single-round infectious SARS-CoV-2 that recapitulates authentic viral replication is presented. But it does not produce wild-type SARS.
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Diagnostic performance of commercial IgM and IgG enzyme-linked immunoassays (ELISAs) for diagnosis of Zika virus infection.

TL;DR: In a setting of endemic dengue transmission, the ZIKV IgM-ELISA had high specificity, but poor sensitivity, whereas the IgG- ELISA is more suitable for ZikV diagnosis among travelers, who reside in areas free of flavivirus transmission, rather than for serosurveys in denge-endemic areas.
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Stability of RNA virus attenuation approaches

TL;DR: This work examines the stability of 3 attenuation strategies for the alphavirus, Venezuelan equine encephalitis virus, and suggests that the chimeric strain combines the initial attenuation of TC-83 with the greater phenotypic stability of V3526, highlighting the importance of the bothInitial attenuation and stability for live-attenuated vaccines.
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Identification and genetic analysis of Panama-genotype Venezuelan equine encephalitis virus subtype ID in Peru.

TL;DR: The recent Iquitos VEE viral isolates were the first Panama-genotype VEE ID virus strains identified outside of the Republic of Panama, and were more closely related to Panamanian ID strains than to isolates previously obtained in Iquito, Peru, or in Colombia and Venezuela.