S
Scott C. Weaver
Researcher at University of Texas Medical Branch
Publications - 584
Citations - 40298
Scott C. Weaver is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Virus & Alphavirus. The author has an hindex of 92, co-authored 536 publications receiving 32230 citations. Previous affiliations of Scott C. Weaver include Mount Sinai St. Luke's and Mount Sinai Roosevelt & Lenox Hill Hospital.
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Deciphering the protective role of adaptive immunity to CHIKV/IRES a novel candidate vaccine against Chikungunya in the A129 mouse model
Haiyan Chu,Subash C. Das,Jeremy Fuchs,M. Suresh,Scott C. Weaver,Dan T. Stinchcomb,Charalambos D. Partidos,Jorge E. Osorio +7 more
TL;DR: The findings demonstrate the immunogenic potential of the CHikV/IRES vaccine and highlight the important role that neutralizing antibodies play in protection against an acute CHIKV infection.
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A Chimeric Vesiculo/Alphavirus Is an Effective Alphavirus Vaccine
TL;DR: A potent experimental vaccine based on a chimeric vesicular stomatitis virus expressing the entire CHIKV envelope polyprotein in place of the VSV glycoprotein (G) has been developed and could have general applicability as alphavirus vaccines.
Journal ArticleDOI
Probing the attenuation and protective efficacy of a candidate chikungunya virus vaccine in mice with compromised interferon (IFN) signaling.
Charalambos D. Partidos,James Weger,Joseph N. Brewoo,Robert L. Seymour,Erin M. Borland,Jeremy P. Ledermann,Ann M. Powers,Scott C. Weaver,Dan T. Stinchcomb,Jorge E. Osorio +9 more
TL;DR: Results highlight the importance of IFNs in controlling CHIK 181/25 vaccine and demonstrate the ability of this vaccine to elicit neutralizing antibody responses that confer short-and long-term protection against wt CHIKV-LR challenge.
Journal ArticleDOI
Nucleotide sequences and phylogeny of the nucleocapsid gene of Oropouche virus.
Mohammad F. Saeed,Heiman Wang,Márcio Roberto Teixeira Nunes,Pedro Fernando da Costa Vasconcelos,Scott C. Weaver,Robert B Shope,Douglas M. Watts,Robert B. Tesh,Alan D.T. Barrett +8 more
TL;DR: The nucleotide sequence of the S RNA segment of the Oropouche (ORO) virus prototype strain TRVL 9760 was determined and found to be 754 nucleotides in length and all the ORO virus strains formed a monophyletic group that comprised three distinct lineages.
Short Report: Serologic Evidence of Arboviral Infections among Humans in Kenya
Laura J. Sutherland,Ayla A. Cash,Yan-Jang Scott Huang,Rosemary Sang,Indu Malhotra,Ann M. Moormann,Christopher L. King,Scott C. Weaver,Charles H. King,A. Desiree LaBeaud +9 more
TL;DR: In this paper, the authors assessed the prevalence of IgG against yellow fever virus (YFV), West Nile virus (WNV), tick-borne encephalitis virus (TBEV), dengue virus serotypes 1-4 (DENV1-4), and chikungunya virus (CHIKV).