S
Shisheng Sun
Researcher at Northwest University (China)
Publications - 57
Citations - 2822
Shisheng Sun is an academic researcher from Northwest University (China). The author has contributed to research in topics: Glycosylation & Glycoprotein. The author has an hindex of 24, co-authored 56 publications receiving 2053 citations. Previous affiliations of Shisheng Sun include Johns Hopkins University School of Medicine & Chinese Ministry of Education.
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Journal ArticleDOI
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Hui Zhang,Tao Liu,Zhen Zhang,Samuel H. Payne,Bai Zhang,Jason E. McDermott,Jian-Ying Zhou,Vladislav A. Petyuk,Li Chen,Debjit Ray,Shisheng Sun,Feng Yang,Lijun Chen,Jing Wang,Punit Shah,Seong Won Cha,Paul Aiyetan,Sunghee Woo,Yuan Tian,Marina A. Gritsenko,Therese R. W. Clauss,Caitlin H. Choi,Matthew E. Monroe,Stefani N. Thomas,Song Nie,Chaochao Wu,Ronald J. Moore,Kun-Hsing Yu,David L. Tabb,David Fenyö,Vineet Bafna,Yue Wang,Henry Rodriguez,Emily S. Boja,Tara Hiltke,Robert Rivers,Lori J. Sokoll,Heng Zhu,Ie Ming Shih,Leslie Cope,Akhilesh Pandey,Bing Zhang,Michael Snyder,Douglas A. Levine,Richard D. Smith,Daniel W. Chan,Karin D. Rodland,Steven A. Carr,Michael A. Gillette,Karl R. Klauser,Eric Kuhn,D. R. Mani,Philipp Mertins,Karen A. Ketchum,Ratna R. Thangudu,Shuang Cai,Mauricio Oberti,Amanda G. Paulovich,Jeffrey R. Whiteaker,Nathan Edwards,Peter B. McGarvey,Subha Madhavan,Pei Wang,Gordon Whiteley,Steven J. Skates,Forest M. White,Christopher R. Kinsinger,Mehdi Mesri,Kenna M. Shaw,Stephen E. Stein,Paul A. Rudnick,Michael Snyder,Yingming Zhao,Xian Chen,David F. Ransohoff,Andrew N. Hoofnagle,Daniel C. Liebler,Melinda E. Sanders,Zhiao Shi,Robbert J.C. Slebos,Lisa J. Zimmerman,Sherri R. Davies,Li Ding,Matthew J. Ellis,R. Reid Townsend +84 more
TL;DR: A view of how the somatic genome drives the cancer proteome and associations between protein and post-translational modification levels and clinical outcomes in HGSC is provided.
Journal ArticleDOI
Comprehensive analysis of protein glycosylation by solid-phase extraction of N -linked glycans and glycosite-containing peptides
Shisheng Sun,Punit Shah,Shadi Toghi Eshghi,Weiming Yang,Namita Trikannad,Shuang Yang,Lijun Chen,Paul Aiyetan,Naseruddin Höti,Zhen Zhang,Daniel W. Chan,Hui Zhang +11 more
TL;DR: A chemoenzymatic method called solid phase extraction of N-linked glycans and glycosite-containing peptides (NGAG) is described for the comprehensive characterization of glycoproteins that is able to determine glycan heterogeneity for individual glycosites in addition to providing information about the total N- linked glycan, glycosite -containing peptide and glycoprotein content of complex samples.
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Hui Zhang,Tao Liu,Zhen Zhang,Samuel H. Payne,Bai Zhang,Jason E. McDermott,Jian-Ying Zhou,Vladislav A. Petyuk,Li Chen,Debjit Ray,Shisheng Sun,Feng Yang,Lijun Chen,Jing Wang,Punit Shah,Seong Won Cha,Paul Aiyetan,Sunghee Woo,Yuan Tian,Marina A. Gritsenko,Therese R. W. Clauss,Caitlin H. Choi,Matthew E. Monroe,Stefani N. Thomas,Song Nie,Chaochao Wu,Ronald J. Moore,Kun-Hsing Yu,David L. Tabb,David Fenyö,Vineet Bafna,Yue Wang,Henry Rodriguez,Emily S. Boja,Tara Hiltke,Robert Rivers,Lori J. Sokoll,Heng Zhu,Ie Ming Shih,Leslie Cope,Akhilesh Pandey,Bing Zhang,Michael Snyder,Douglas A. Levine,Richard D. Smith,Daniel W. Chan,Karin D. Rodland,Steven A. Carr,Michael A. Gillette,Karl R. Klauser,Eric Kuhn,D. R. Mani,Philipp Mertins,Karen A. Ketchum,Ratna R. Thangudu,Shuang Cai,Mauricio Oberti,Amanda G. Paulovich,Jeffrey R. Whiteaker,Nathan Edwards,Peter B. McGarvey,Subha Madhavan,Pei Wang,Gordon Whiteley,Steven J. Skates,Forest M. White,Christopher R. Kinsinger,Mehdi Mesri,Kenna M. Shaw,Stephen E. Stein,Paul A. Rudnick,Michael Snyder,Yingming Zhao,Xian Chen,David F. Ransohoff,Andrew N. Hoofnagle,Daniel C. Liebler,Melinda E. Sanders,Zhiao Shi,Robbert J.C. Slebos,Lisa J. Zimmerman,Sherri R. Davies,Li Ding,Matthew J. Ellis,R. Reid Townsend +84 more
TL;DR: In this article, a detailed analysis of the molecular components and underlying mechanisms associated with ovarian cancer was provided, such as how different copy-number alterna-tions in the Proteome, the proteins associated with chromosomal instability, the sets of signalingpathways that diverse genome rearrangements converge on, and the ones associated with short overall survival.
Journal ArticleDOI
Glycosylation Site Alteration in the Evolution of Influenza A (H1N1) Viruses
TL;DR: The results showed that influenza H1N1 viruses underwent different alterations of protein glycosylation in different hosts, and the significant role of positional alteration of gly cosylation sites in the host adaptation of influenza virus was elucidated.
Journal ArticleDOI
An analysis of the sensitivity of proteogenomic mapping of somatic mutations and novel splicing events in cancer
Kelly V. Ruggles,Zuojian Tang,Xuya Wang,Himanshu Grover,Manor Askenazi,Jennifer Teubl,Song Cao,Michael D. McLellan,Karl R. Clauser,David L. Tabb,Philipp Mertins,Robbert J.C. Slebos,Petra Erdmann-Gilmore,Shunqiang Li,Harsha P. Gunawardena,Ling Xie,Tao Liu,Jian-Ying Zhou,Shisheng Sun,Katherine A. Hoadley,Charles M. Perou,Xian Chen,Sherri R. Davies,Christopher G. Maher,Christopher R. Kinsinger,Karen D. Rodland,Hui Zhang,Zhen Zhang,Li Ding,Raymond R. Townsend,Henry Rodriguez,Daniel W. Chan,Richard D. Smith,Daniel C. Liebler,Steven A. Carr,Samuel H. Payne,Matthew J. Ellis,David Fenyő +37 more
TL;DR: This large-scale proteogenomic integration allowed us to determine the degree to which mutations are translated and identify gaps in sequence coverage, thereby benchmarking current technology and progress toward whole cancer proteome and transcriptome analysis.