Z
Zuojian Tang
Researcher at New York University
Publications - 33
Citations - 2867
Zuojian Tang is an academic researcher from New York University. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 17, co-authored 33 publications receiving 2525 citations. Previous affiliations of Zuojian Tang include McGill University & Indiana University.
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Journal ArticleDOI
The ecoresponsive genome of Daphnia pulex
John K. Colbourne,Michael E. Pfrender,Michael E. Pfrender,Donald L. Gilbert,W. Kelley Thomas,Abraham E. Tucker,Abraham E. Tucker,Todd H. Oakley,Shin-ichi Tokishita,Andrea Aerts,Georg J. Arnold,Malay Kumar Basu,Malay Kumar Basu,Darren J Bauer,Carla E. Cáceres,Liran Carmel,Liran Carmel,Claudio Casola,Jeong Hyeon Choi,John C. Detter,Qunfeng Dong,Qunfeng Dong,Serge Dusheyko,Brian D. Eads,Thomas Fröhlich,Kerry Geiler-Samerotte,Kerry Geiler-Samerotte,Daniel Gerlach,Daniel Gerlach,Phil Hatcher,Sanjuro Jogdeo,Sanjuro Jogdeo,Jeroen Krijgsveld,Evgenia V. Kriventseva,Dietmar Kültz,Christian Laforsch,Erika Lindquist,Jacqueline Lopez,J. Robert Manak,J. Robert Manak,Jean Muller,Jasmyn Pangilinan,Rupali P Patwardhan,Rupali P Patwardhan,Samuel Pitluck,Ellen J. Pritham,Andreas Rechtsteiner,Andreas Rechtsteiner,Mina Rho,Igor B. Rogozin,Onur Sakarya,Onur Sakarya,Asaf Salamov,Sarah Schaack,Sarah Schaack,Harris Shapiro,Yasuhiro Shiga,Courtney Skalitzky,Zachary Smith,Alexander Souvorov,Way Sung,Zuojian Tang,Zuojian Tang,Dai Tsuchiya,Hank Tu,Hank Tu,Harmjan R. Vos,Mei Wang,Yuri I. Wolf,Hideo Yamagata,Takuji Yamada,Yuzhen Ye,Joseph R. Shaw,Justen Andrews,Teresa J. Crease,Haixu Tang,Susan Lucas,Hugh M. Robertson,Peer Bork,Eugene V. Koonin,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Igor V. Grigoriev,Michael Lynch,Jeffrey L. Boore,Jeffrey L. Boore +85 more
TL;DR: The Daphnia genome reveals a multitude of genes and shows adaptation through gene family expansions, and the coexpansion of gene families interacting within metabolic pathways suggests that the maintenance of duplicated genes is not random.
Journal ArticleDOI
Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
Panagiotis Ntziachristos,Panagiotis Ntziachristos,Aristotelis Tsirigos,Pieter Van Vlierberghe,Jelena Nedjic,Thomas Trimarchi,Maria Sol Flaherty,Dolors Ferres-Marco,Vanina Gabriela Da Ros,Zuojian Tang,Jasmin M. Siegle,Patrik Asp,Michael Hadler,Isaura Rigo,Kim De Keersmaecker,Kim De Keersmaecker,Jay P. Patel,Tien Huynh,Filippo Utro,Sandrine Poglio,Jeremy B. Samon,Elisabeth Paietta,Janis Racevskis,Jacob M. Rowe,Raul Rabadan,Ross L. Levine,Stuart M. Brown,Françoise Pflumio,Maria Dominguez,Adolfo A. Ferrando,Iannis Aifantis +30 more
TL;DR: It is demonstrated that activation of NOTCH1 specifically induces loss of the repressive mark lysine-27 tri-methylation of histone 3 (H3K27me3)4 by antagonizing the activity of the Polycomb Repressive Complex 2 (PRC2) complex.
Journal ArticleDOI
Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia.
Julia Meyer,Jinhua Wang,Laura E. Hogan,Laura E. Hogan,Jun J. Yang,Smita Dandekar,Jay P. Patel,Zuojian Tang,Paul Zumbo,Sheng-Bo Li,Jiri Zavadil,Ross L. Levine,Timothy Cardozo,Stephen P. Hunger,Stephen P. Hunger,Elizabeth A. Raetz,William E. Evans,Debra J. Morrison,Christopher E. Mason,William L. Carroll +19 more
TL;DR: Results suggest that mutations in NT5C2 are associated with the outgrowth of drug-resistant clones in ALL, and base substitutions conferred increased enzymatic activity and resistance to treatment with nucleoside analog therapies.
Journal ArticleDOI
Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond
Leslie A. Mitchell,Ann Wang,Ann Wang,Giovanni Stracquadanio,Giovanni Stracquadanio,Giovanni Stracquadanio,Zheng Kuang,Xuya Wang,Kun Yang,Kun Yang,Sarah M. Richardson,J. Andrew Martin,Yu Zhao,Roy Walker,Yisha Luo,Hongjiu Dai,Kang Dong,Zuojian Tang,Yanling Yang,Yizhi Cai,Adriana Heguy,Beatrix Ueberheide,David Fenyö,Junbiao Dai,Joel S. Bader,Joel S. Bader,Jef D. Boeke +26 more
TL;DR: Analyses of phenotypes, transcriptomics, and proteomics of synVI and poly-syn strains reveal, in general, WT cell properties and the existence of rare bugs resulting from genome editing.
Journal ArticleDOI
An analysis of the sensitivity of proteogenomic mapping of somatic mutations and novel splicing events in cancer
Kelly V. Ruggles,Zuojian Tang,Xuya Wang,Himanshu Grover,Manor Askenazi,Jennifer Teubl,Song Cao,Michael D. McLellan,Karl R. Clauser,David L. Tabb,Philipp Mertins,Robbert J.C. Slebos,Petra Erdmann-Gilmore,Shunqiang Li,Harsha P. Gunawardena,Ling Xie,Tao Liu,Jian-Ying Zhou,Shisheng Sun,Katherine A. Hoadley,Charles M. Perou,Xian Chen,Sherri R. Davies,Christopher G. Maher,Christopher R. Kinsinger,Karen D. Rodland,Hui Zhang,Zhen Zhang,Li Ding,Raymond R. Townsend,Henry Rodriguez,Daniel W. Chan,Richard D. Smith,Daniel C. Liebler,Steven A. Carr,Samuel H. Payne,Matthew J. Ellis,David Fenyő +37 more
TL;DR: This large-scale proteogenomic integration allowed us to determine the degree to which mutations are translated and identify gaps in sequence coverage, thereby benchmarking current technology and progress toward whole cancer proteome and transcriptome analysis.