Y
Yuan Tian
Researcher at Johns Hopkins University
Publications - 65
Citations - 3208
Yuan Tian is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 25, co-authored 52 publications receiving 2532 citations. Previous affiliations of Yuan Tian include University of Mississippi Medical Center & Institute for Systems Biology.
Papers
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Journal ArticleDOI
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Hui Zhang,Tao Liu,Zhen Zhang,Samuel H. Payne,Bai Zhang,Jason E. McDermott,Jian-Ying Zhou,Vladislav A. Petyuk,Li Chen,Debjit Ray,Shisheng Sun,Feng Yang,Lijun Chen,Jing Wang,Punit Shah,Seong Won Cha,Paul Aiyetan,Sunghee Woo,Yuan Tian,Marina A. Gritsenko,Therese R. W. Clauss,Caitlin H. Choi,Matthew E. Monroe,Stefani N. Thomas,Song Nie,Chaochao Wu,Ronald J. Moore,Kun-Hsing Yu,David L. Tabb,David Fenyö,Vineet Bafna,Yue Wang,Henry Rodriguez,Emily S. Boja,Tara Hiltke,Robert Rivers,Lori J. Sokoll,Heng Zhu,Ie Ming Shih,Leslie Cope,Akhilesh Pandey,Bing Zhang,Michael Snyder,Douglas A. Levine,Richard D. Smith,Daniel W. Chan,Karin D. Rodland,Steven A. Carr,Michael A. Gillette,Karl R. Klauser,Eric Kuhn,D. R. Mani,Philipp Mertins,Karen A. Ketchum,Ratna R. Thangudu,Shuang Cai,Mauricio Oberti,Amanda G. Paulovich,Jeffrey R. Whiteaker,Nathan Edwards,Peter B. McGarvey,Subha Madhavan,Pei Wang,Gordon Whiteley,Steven J. Skates,Forest M. White,Christopher R. Kinsinger,Mehdi Mesri,Kenna M. Shaw,Stephen E. Stein,Paul A. Rudnick,Michael Snyder,Yingming Zhao,Xian Chen,David F. Ransohoff,Andrew N. Hoofnagle,Daniel C. Liebler,Melinda E. Sanders,Zhiao Shi,Robbert J.C. Slebos,Lisa J. Zimmerman,Sherri R. Davies,Li Ding,Matthew J. Ellis,R. Reid Townsend +84 more
TL;DR: A view of how the somatic genome drives the cancer proteome and associations between protein and post-translational modification levels and clinical outcomes in HGSC is provided.
Journal ArticleDOI
Solid-phase extraction of N-linked glycopeptides.
TL;DR: A protocol for solid-phase extraction of N-linked glycopeptides and subsequent identification of N -linked glycosylation sites (N-glycosites) by tandem mass spectrometry is described.
Journal ArticleDOI
Proteomic Analysis of Chinese Hamster Ovary Cells
Deniz Baycin-Hizal,David L. Tabb,Raghothama Chaerkady,Lily Chen,Nathan E. Lewis,Harish Nagarajan,Vishaldeep Sarkaria,Amit Kumar,Daniel Wolozny,Joe Colao,Elena F. Jacobson,Yuan Tian,Robert N. O'Meally,Sharon S. Krag,Robert N. Cole,Bernhard O. Palsson,Hui Zhang,Michael J. Betenbaugh +17 more
TL;DR: This first large-scale proteomic analysis of Chinese hamster ovary (CHO) cells will enhance the knowledge base about CHO capabilities for recombinant expression and provide information useful in cell engineering efforts aimed at modifying CHO cellular functions.
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Hui Zhang,Tao Liu,Zhen Zhang,Samuel H. Payne,Bai Zhang,Jason E. McDermott,Jian-Ying Zhou,Vladislav A. Petyuk,Li Chen,Debjit Ray,Shisheng Sun,Feng Yang,Lijun Chen,Jing Wang,Punit Shah,Seong Won Cha,Paul Aiyetan,Sunghee Woo,Yuan Tian,Marina A. Gritsenko,Therese R. W. Clauss,Caitlin H. Choi,Matthew E. Monroe,Stefani N. Thomas,Song Nie,Chaochao Wu,Ronald J. Moore,Kun-Hsing Yu,David L. Tabb,David Fenyö,Vineet Bafna,Yue Wang,Henry Rodriguez,Emily S. Boja,Tara Hiltke,Robert Rivers,Lori J. Sokoll,Heng Zhu,Ie Ming Shih,Leslie Cope,Akhilesh Pandey,Bing Zhang,Michael Snyder,Douglas A. Levine,Richard D. Smith,Daniel W. Chan,Karin D. Rodland,Steven A. Carr,Michael A. Gillette,Karl R. Klauser,Eric Kuhn,D. R. Mani,Philipp Mertins,Karen A. Ketchum,Ratna R. Thangudu,Shuang Cai,Mauricio Oberti,Amanda G. Paulovich,Jeffrey R. Whiteaker,Nathan Edwards,Peter B. McGarvey,Subha Madhavan,Pei Wang,Gordon Whiteley,Steven J. Skates,Forest M. White,Christopher R. Kinsinger,Mehdi Mesri,Kenna M. Shaw,Stephen E. Stein,Paul A. Rudnick,Michael Snyder,Yingming Zhao,Xian Chen,David F. Ransohoff,Andrew N. Hoofnagle,Daniel C. Liebler,Melinda E. Sanders,Zhiao Shi,Robbert J.C. Slebos,Lisa J. Zimmerman,Sherri R. Davies,Li Ding,Matthew J. Ellis,R. Reid Townsend +84 more
TL;DR: In this article, a detailed analysis of the molecular components and underlying mechanisms associated with ovarian cancer was provided, such as how different copy-number alterna-tions in the Proteome, the proteins associated with chromosomal instability, the sets of signalingpathways that diverse genome rearrangements converge on, and the ones associated with short overall survival.
Journal ArticleDOI
A Novel Collagen Matricryptin Reduces Left Ventricular Dilation Post-Myocardial Infarction by Promoting Scar Formation and Angiogenesis.
Merry L. Lindsey,Rugmani Padmanabhan Iyer,Rogelio Zamilpa,Andriy Yabluchanskiy,Kristine Y. DeLeon-Pennell,Michael E. Hall,Abdullah Kaplan,Fouad A. Zouein,Dustin R. Bratton,Elizabeth R. Flynn,Presley L. Cannon,Yuan Tian,Yu-Fang Jin,Richard A. Lange,Dorota Tokmina-Roszyk,Gregg B. Fields,Lisandra E. de Castro Brás,Lisandra E. de Castro Brás,Lisandra E. de Castro Brás +18 more
TL;DR: Collagen Iα1 matricryptin p1158/59 facilitates LV remodeling post-MI by regulating scar formation through targeted ECM generation and stimulation of angiogenesis.