S
Sina Bavari
Researcher at United States Army Medical Research Institute of Infectious Diseases
Publications - 353
Citations - 21495
Sina Bavari is an academic researcher from United States Army Medical Research Institute of Infectious Diseases. The author has contributed to research in topics: Ebola virus & Virus. The author has an hindex of 69, co-authored 349 publications receiving 18782 citations. Previous affiliations of Sina Bavari include University of Nebraska Medical Center & Walter Reed Army Institute of Research.
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High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses.
Rajini Mudhasani,Krishna P. Kota,Cary Retterer,Julie P. Tran,Chris A. Whitehouse,Sina Bavari +5 more
TL;DR: High content image-based screening was developed as an approach to test a protease inhibitor small molecule library for antiviral activity against Rift Valley fever virus and to determine their mechanism of action and any possible deleterious effects on host cellular biology and demonstrates that high-content image analysis can be used to screen chemical libraries for new antivirals.
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Potentiation of Inhaled Staphylococcal Enterotoxin B-Induced Toxicity by Lipopolysaccharide in Mice
Ross D. LeClaire,Robert E. Hunt,Sina Bavari,James E. Estep,Gene O. Nelson,Catherine L. Wilhelmsen +5 more
TL;DR: This paper investigated the potentiation of staphylococcal enterotoxin B (SEB) inhalation toxicity by lipopolysaccharide (LPS) in BALB/c mice.
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Characterization of clinical and immunological parameters during Ebola virus infection of rhesus macaques.
Karen A. Martins,Christopher L. Cooper,Travis K. Warren,Jay Wells,Bell T,Raymond J,Kelly S. Stuthman,Jacqueline G. Benko,Nicole L. Garza,van Tongeren S,Ginger Donnelly,Cary Retterer,Dong L,Sina Bavari +13 more
TL;DR: In this paper, pathological and immunological data from EBOV-infected rhesus macaques are presented, including changes in blood chemistries, hematology, coagulation, and immune parameters during infection, which were consistently observed in the animals.
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Animal models for ebolavirus countermeasures discovery: what defines a useful model?
Amy C. Shurtleff,Sina Bavari +1 more
TL;DR: Complete development and licensure of therapeutic agents and vaccines will require demonstration that mechanisms conferring protection in NHP models of infection are predictive of protective responses in humans, for a given countermeasure.
Journal ArticleDOI
Development of cell-based assays to measure botulinum neurotoxin serotype A activity using cleavage-sensitive antibodies.
Jonathan E. Nuss,Gordon Ruthel,Lyal E. Tressler,Laura M. Wanner,Edna Torres-Melendez,Martha L. Hale,Sina Bavari +6 more
TL;DR: Novel BoNT serotype A (BoNT/A) cleavage-sensitive (BACS) antibodies that only interact with full-length SNAP-25 (synaptosomal-associated protein of 25 kDa) are developed, allowing for the high-throughput evaluation of experimental compounds.