S
Sina Bavari
Researcher at United States Army Medical Research Institute of Infectious Diseases
Publications - 353
Citations - 21495
Sina Bavari is an academic researcher from United States Army Medical Research Institute of Infectious Diseases. The author has contributed to research in topics: Ebola virus & Virus. The author has an hindex of 69, co-authored 349 publications receiving 18782 citations. Previous affiliations of Sina Bavari include University of Nebraska Medical Center & Walter Reed Army Institute of Research.
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Journal ArticleDOI
Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization
Mansour Mohamadzadeh,Scott D. Olson,Warren V. Kalina,Gordon Ruthel,Gretchen L. Demmin,Kelly L. Warfield,Sina Bavari,Todd R. Klaenhammer +7 more
TL;DR: The results emphasize a potentially important role for lactobacilli in modulating immunological functions of DCs and suggest that certain strains could be particularly advantageous as vaccine adjuvants, by promoting DCs to regulate T cell responses toward T helper 1 and Tc1 pathways.
Journal ArticleDOI
Lipid Raft Microdomains A Gateway for Compartmentalized Trafficking of Ebola and Marburg Viruses
Sina Bavari,Catharine M. Bosio,Elizabeth Wiegand,Gordon Ruthel,Amy B. Will,Thomas W. Geisbert,Michael Hevey,Connie S. Schmaljohn,Alan L. Schmaljohn,M. Javad Aman +9 more
TL;DR: The compartmentalization of Ebola and Marburg viral proteins within lipid rafts during viral assembly and budding is reported, suggesting that viral exit occurs at the rafts and that the entry of filoviruses requires functional rafts.
Journal ArticleDOI
Taxonomy of the order Mononegavirales: update 2016
Claudio L. Afonso,Gaya K. Amarasinghe,Krisztián Bányai,Yīmíng Bào,Christopher F. Basler,Sina Bavari,Nicolás Bejerman,Kim R. Blasdell,François Xavier Briand,Thomas Briese,Alexander Bukreyev,Charles H. Calisher,Kartik Chandran,Jiāsēn Chéng,Anna N. Clawson,Peter L. Collins,Ralf G. Dietzgen,Olga Dolnik,Leslie L. Domier,Ralf Dürrwald,John M. Dye,Andrew J. Easton,Hideki Ebihara,Szilvia L. Farkas,Juliana Freitas-Astúa,Pierre Formenty,Ron A. M. Fouchier,Yanping Fu,Elodie Ghedin,Michael M. Goodin,Roger Hewson,Masayuki Horie,Timothy H. Hyndman,Dàohóng Jiāng,E. W. Kitajima,Gary P. Kobinger,Hideki Kondo,Gael Kurath,Robert A. Lamb,Sergio Lenardon,Eric M. Leroy,C. Li,Xian Dan Lin,Lìjiāng Liú,Ben Longdon,Szilvia Marton,Andrea Maisner,Elke Mühlberger,Sergey V. Netesov,Norbert Nowotny,Norbert Nowotny,Jean L. Patterson,Susan Payne,Janusz T. Paweska,Richard E. Randall,Bertus K. Rima,Paul A. Rota,Dennis Rubbenstroth,Martin Schwemmle,Mang Shi,Sophie J. Smither,Mark D. Stenglein,David M. Stone,Ayato Takada,Calogero Terregino,Robert B. Tesh,Jun Hua Tian,Keizo Tomonaga,Noël Tordo,Jonathan S. Towner,Nikos Vasilakis,Martin Verbeek,Viktor E. Volchkov,Victoria Wahl-Jensen,John A. Walsh,Peter J. Walker,David Wang,Lin-Fa Wang,Thierry Wetzel,Anna E. Whitfield,Jiǎtāo Xiè,Kwok-Yung Yuen,Yong-Zhen Zhang,Jens H. Kuhn +83 more
TL;DR: The updated taxonomy of the order Mononegavirales is presented as now accepted by the International Committee on Taxonomy of Viruses (ICTV).
Journal ArticleDOI
Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose
Jasdave S. Chahal,Omar F. Khan,Christopher L. Cooper,Justine S. McPartlan,Jonathan K. Tsosie,Lucas D. Tilley,Saima M. Sidik,Sebastian Lourido,Robert Langer,Sina Bavari,Hidde L. Ploegh,Daniel G. Anderson +11 more
TL;DR: In this article, the authors developed a rapid response, fully synthetic, single-dose, adjuvant-free dendrimer nanoparticle vaccine platform wherein antigens are encoded by encapsulated mRNA replicons.
Journal ArticleDOI
Ebola and Marburg Viruses Replicate in Monocyte-Derived Dendritic Cells without Inducing the Production of Cytokines and Full Maturation
Catharine M. Bosio,M. Javad Aman,Case C. Grogan,Robert J. Hogan,Gordon Ruthel,Diane L. Negley,Mansour Mohamadzadeh,Sina Bavari,Alan L. Schmaljohn +8 more
TL;DR: It is demonstrated that EBOV and MARV infected and replicated in primary human DCs without inducing cytokine secretion, and DCs are disabled, and an effective early host response is delayed by the necessary reliance on less-efficient secondary mechanisms.