S
Sofia-Iris Bibli
Researcher at Goethe University Frankfurt
Publications - 23
Citations - 768
Sofia-Iris Bibli is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Ischemia & Enos. The author has an hindex of 12, co-authored 22 publications receiving 436 citations. Previous affiliations of Sofia-Iris Bibli include National and Kapodistrian University of Athens.
Papers
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Journal ArticleDOI
Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice
Constantinos Glynos,Sofia-Iris Bibli,Sofia-Iris Bibli,Paraskevi Katsaounou,Athanasia Pavlidou,Christina Magkou,Vassiliki Karavana,Stavros Topouzis,Ioannis Kalomenidis,Spyros Zakynthinos,Andreas Papapetropoulos +10 more
TL;DR: Exposure to e-cig vapor can trigger inflammatory responses and adversely affect respiratory system mechanics and it is concluded that both e- cig vaping and conventional cigarette smoking negatively impact lung biology.
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Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction
Lukas Tombor,David John,Simone F. Glaser,Guillermo Luxán,Elvira Forte,Milena B. Furtado,Nadia A. Rosenthal,Nina Baumgarten,Marcel H. Schulz,Janina Wittig,Eva-Maria Rogg,Yosif Manavski,Ariane Fischer,Marion Muhly-Reinholz,Kathrin Klee,Mario Looso,Carmen Selignow,Till Acker,Sofia-Iris Bibli,Ingrid Fleming,Ralph Patrick,Ralph Patrick,Richard P. Harvey,Richard P. Harvey,Wesley Abplanalp,Stefanie Dimmeler +25 more
TL;DR: In this paper, the authors explore the kinetics and individual cellular responses of endothelial cells after myocardial infarction by using single cell RNA sequencing and demonstrate a time dependent switch in endothelial cell proliferation and inflammation associated with transient changes in metabolic gene signatures.
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Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism
Ioanna Andreadou,Emmanuel Mikros,Konstantinos Ioannidis,Fragiska Sigala,Katerina K. Naka,Sarantos Kostidis,Dimitrios Farmakis,Roxane Tenta,Nikolaos Kavantzas,Sofia-Iris Bibli,Evangelos Gikas,Leandros Skaltsounis,Dimitrios Th. Kremastinos,Efstathios K. Iliodromitis +13 more
TL;DR: Activation of AMPK and suppression of iNOS by oleuropein seem to prevent the structural, functional and histopathological cardiac effects of chronic DXR toxicity.
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Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation.
Rubén Marín-Juez,Hadil El-Sammak,Christian S. M. Helker,Aosa Kamezaki,Sri Teja Mullapuli,Sofia-Iris Bibli,Matthew J. Foglia,Ingrid Fleming,Kenneth D. Poss,Didier Y.R. Stainier +9 more
TL;DR: It is shown that revascularization requires a coordinated multi-tissue response culminating with the formation of a complex vascular network available as a scaffold for cardiomyocyte repopulation.
Journal ArticleDOI
Pleiotropic effects of laminar flow and statins depend on the Krüppel-like factor-induced lncRNA MANTIS
Matthias S. Leisegang,Sofia-Iris Bibli,Stefan Günther,Beatrice Pflüger-Müller,James A. Oo,Cindy Höper,Sandra Seredinski,Michail Yekelchyk,Thomas Schmitz-Rixen,Christoph Schürmann,Jiong Hu,Mario Looso,Fragiska Sigala,Reinier A. Boon,Reinier A. Boon,Ingrid Fleming,Ralf P. Brandes +16 more
TL;DR: MANTIS is tightly regulated by the transcription factors KLF2 and KLF4 and limits the ICAM-1 mediated monocyte adhesion to endothelial cells and thus potentially atherosclerosis development in humans.