S
Stephan R. Targan
Researcher at Cedars-Sinai Medical Center
Publications - 577
Citations - 61849
Stephan R. Targan is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 108, co-authored 545 publications receiving 58069 citations. Previous affiliations of Stephan R. Targan include University of Münster & Mount Sinai Hospital, Toronto.
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Patent
DIAGNOSIS, PREVENTION AND TREATMENT OF CROHN'S DISEASE USING THE OmpC ANTIGEN
TL;DR: In this paper, a method of diagnosing Crohn's disease in a subject by determining the presence or absence of or IgA anti-OmpC antibodies in the subject, where the presence of the IAC antibodies indicates that the subject has Crohn disease.
Journal ArticleDOI
Sustained tl1a (tnfsf15) expression on both lymphoid and myeloid cells leads to mild spontaneous intestinal inflammation and fibrosis.
Libo Zheng,Xiaolan Zhang,Jeremy J.W. Chen,Ryan Ichikawa,Kori Wallace,Charalabos Pothoulakis,Hon Wai Koon,Stephan R. Targan,David Q. Shih +8 more
TL;DR: It is confirmed that TL1A-DR3 interaction is involved in T cell-dependent ileitis and fibrosis, and T cells with constitutive expression of Tl1a in both lymphoid and myeloid cells were found to have a more activated phenotype and increased gut homing marker CCR9 expression.
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Colorectal cancer screening and surveillance in Crohn's colitis
Robert J. Basseri,Benjamin Basseri,Maria Vassilaki,Gil Y. Melmed,Andrew Ippoliti,Eric A. Vasiliauskas,Philip Fleshner,Juan Lechago,Bing Hu,Dror Berel,Stephan R. Targan,Konstantinos A. Papadakis +11 more
TL;DR: In this paper, colonoscopy and biopsy records from patients with colonic Crohn's disease were evaluated at the Cedars-Sinai Inflammatory Bowel Disease Center during a 17-year period (19922009).
Journal ArticleDOI
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility
Aleksejs Sazonovs,Christine Stevens,Guhan Venkataraman,K. Yuan,Brandon E Avila,Maria T. Abreu,Tariq Ahmad,Matthieu Allez,Ashwin N. Ananthakrishnan,Gil Atzmon,Aris Baras,Jeffrey C. Barrett,Nir Barzilai,Laurent Beaugerie,Ashley Beecham,Charles N. Bernstein,Alain Bitton,Bernd Bokemeyer,Andrew T. Chan,Daniel Chung,Isabelle Cleynen,Jacques Cosnes,David M. Cutler,Allan Daly,Oriana M. Damas,Lisa W. Datta,Noor Dawany,Marcella Devoto,Sheila Dodge,Eva Ellinghaus,Laura Fachal,M. Farkkila,William A. Faubion,Manuel A. R. Ferreira,Denis Franchimont,Stacey Gabriel,Tian Ge,Michel Georges,Kyle Gettler,Mamta Giri,Benjamin Glaser,Siegfried Goerg,Philippe Goyette,Daniel B. Graham,Eija Hämäläinen,Talin Haritunians,Graham A. Heap,Mikko Hiltunen,Marc P. Hoeppner,Julie Horowitz,Peter M. Irving,Vivek Iyer,Chaim Jalas,Judith R. Kelsen,Hamed Khalili,Barbara S. Kirschner,Kimmo Kontula,Jukka Koskela,Subra Kugathasan,Juozas Kupcinskas,Christopher A. Lamb,Matthias Laudes,Chloé Lévesque,Adam P. Levine,James D. Lewis,Claire Liefferinckx,B. Loescher,Edouard Louis,John C. Mansfield,Sandra May,Jacob L. McCauley,Emebet Mengesha,Myriam Mni,Paul Moayyedi,Christopher J. Moran,Rodney D. Newberry,Sirimon O-Charoen,David T. Okou,Bas Oldenburg,Harry Ostrer,Aarno Palotie,Jean-Michel Paquette,Joel Pekow,Inga Peter,Marieke Pierik,Cyriel Y. Ponsioen,Nikolas Pontikos,Natalie J. Prescott,Ann E. Pulver,Souad Rahmouni,Daniel L. Rice,Päivi Saavalainen,Bruce E. Sands,R. Balfour Sartor,Elena R. Schiff,Stefan Schreiber,L. Philip Schumm,Anthony W. Segal,Philippe Seksik,Rasha Shawky,Shehzad Z. Sheikh,Mark S. Silverberg,Alison Simmons,Jurgita Skeiceviciene,Harry Sokol,Matthew Solomonson,Hari K. Somineni,Dylan Sun,Stephan R. Targan,Dan Turner,Holm H. Uhlig,Andrea Van Der Meulen,Severine Vermeire,Sare Verstockt,Michiel Voskuil,Harland S. Winter,J. Young,Richard H. Duerr,Andre Franke,Steven R. Brant,Judy H. Cho,Rinse K. Weersma,Miles Parkes,Ramnik J. Xavier,Manuel A. Rivas,John D. Rioux,Dermot P.B. McGovern,Hailiang Huang,Carl A. Anderson,Mark J. Daly +129 more
TL;DR: In this article , a large-scale sequence-based analysis identifies novel risk variants and susceptibility genes for Crohn's disease, and implicates mesenchymal cell-mediated intestinal homeostasis in disease etiology.