T
Thomas Foltynie
Researcher at UCL Institute of Neurology
Publications - 381
Citations - 26959
Thomas Foltynie is an academic researcher from UCL Institute of Neurology. The author has contributed to research in topics: Deep brain stimulation & Parkinson's disease. The author has an hindex of 80, co-authored 352 publications receiving 21023 citations. Previous affiliations of Thomas Foltynie include University College London & University of Kent.
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Journal ArticleDOI
Neural signatures of hyperdirect pathway activity in Parkinson's disease.
Ashwini Oswal,Ashwini Oswal,Chunyan Cao,Chien-Hung Yeh,Chien-Hung Yeh,Wolf-Julian Neumann,James Gratwicke,Harith Akram,Andreas Horn,Dianyou Li,Shikun Zhan,Chao Zhang,Qiang Wang,Ludvic Zrinzo,Thomas Foltynie,Patricia Limousin,Rafal Bogacz,Bomin Sun,Masud Husain,Peter Brown,Vladimir Litvak +20 more
TL;DR: In this paper, the relationship between the anatomy of this circuit and oscillatory synchronisation within it was investigated by combining recordings from human subthalamic nucleus (STN) and internal globus pallidus (GPi) with magnetoencephalography, tractography and computational modelling.
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Equating scores of the University of Pennsylvania Smell Identification Test and Sniffin' Sticks test in patients with Parkinson's disease
Michael T. Lawton,Michele T.M. Hu,Fahd Baig,Claudio Ruffmann,Eilidh Barron,Diane M A Swallow,Naveed Malek,Katherine A Grosset,Nin Bajaj,Roger A. Barker,Nigel Williams,David J. Burn,Thomas Foltynie,Huw R. Morris,Nicholas W. Wood,Margaret T May,Donald G. Grosset,Yoav Ben-Shlomo +17 more
TL;DR: It is demonstrated that one can convert UPSIT to B-SIT or Sniffin' 16, and Sniffin’ 12 to 16 scores in a valid way, which can facilitate direct comparison between tests aiding future collaborative analyses and evidence synthesis.
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11C-PE2I and 18F-Dopa PET for assessing progression rate in Parkinson's: A longitudinal study
Weihua Li,Nicholas P. Lao-Kaim,Andreas A. Roussakis,Antonio Martin-Bastida,Natalie Valle-Guzman,Gesine Paul,Clare Loane,Håkan Widner,Marios Politis,Thomas Foltynie,Roger A. Barker,Paola Piccini +11 more
TL;DR: This study directly compares 18F‐dopa with the highly selective dopamine transporter radioligand 11C‐PE2I for the assessment of motor severity and rate of progression in Parkinson's disease.
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Subthalamic Nucleus Local Field Potential Activity Helps Encode Motor Effort Rather Than Force in Parkinsonism
Huiling Tan,Alek Pogosyan,Keyoumars Ashkan,Binith Cheeran,James J. FitzGerald,Alexander L. Green,Tipu Z. Aziz,Thomas Foltynie,Patricia Limousin,Ludvic Zrinzo,Peter Brown,Peter Brown +11 more
TL;DR: The results argue against the hypothesis that the basal ganglia are directly involved in the parameterization of force during movement and support a role of the STN in the control of motor effort to be attributed to a response.
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Development and external validation of a prognostic model in newly diagnosed Parkinson disease
Daan C. Velseboer,Rob M.A. de Bie,Luuk Wieske,Jonathan R. Evans,Sarah L Mason,Thomas Foltynie,Ben Schmand,Rob J. de Haan,Bart Post,Roger A. Barker,Caroline H. Williams-Gray +10 more
TL;DR: A model that allows individual patient prognostication at 5 years from diagnosis, using a small set of predictor variables that can easily be obtained by clinicians or research nurses is constructed.