Thomas Foltynie

TL;DR: This review provides an up-to-date repository and synthesis of the current literature regarding technology used for assessing limb bradykinesia in PD and discusses the current trends with regards to technology.

TL;DR: Cranial MRI at 3T can readily produce heating exceeding international guidelines, patients with ActivaPC Medtronic systems are safe to be recruited to future fMRI experiments performed under the specific conditions defined by the protocol, with no likelihood of confound by inappropriate stimulus delivery.

TL;DR: The results enhance the understanding of how the basal ganglia control gripping force, and suggest that deep brain LFPs could potentially be used to decode movement parameters related to force and movement vigour for the development of advanced human-machine interfaces.

TL;DR: Low frequency NBM DBS can be safely conducted in DLB patients and its potential effects on both clinical symptoms and functional connectivity in underlying cognitive networks are explored, encouraging further exploration of the possible effects of stimulation on neuropsychiatric symptoms and corresponding changes infunctional connectivity in cognitive networks.

TL;DR: Frequency specific oscillatory activities in the subthalamic nucleus region (STNr) impact on motor performance from the beginning to the end of a voluntary grip and that deficiencies of such activities lead to motor impairments are suggested.