T
Thomas Foltynie
Researcher at UCL Institute of Neurology
Publications - 381
Citations - 26959
Thomas Foltynie is an academic researcher from UCL Institute of Neurology. The author has contributed to research in topics: Deep brain stimulation & Parkinson's disease. The author has an hindex of 80, co-authored 352 publications receiving 21023 citations. Previous affiliations of Thomas Foltynie include University College London & University of Kent.
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Journal ArticleDOI
Genetic and pathological links between Parkinson's disease and the lysosomal disorder Sanfilippo syndrome†‡§
Sophie Winder-Rhodes,P Garcia-Reitbock,P Garcia-Reitbock,Maria Ban,Evans,Thomas S. Jacques,A Kemppinen,Thomas Foltynie,Caroline H. Williams-Gray,Patrick F. Chinnery,Gavin Hudson,David J. Burn,Liesl M. Allcock,Stephen Sawcer,Roger A. Barker,Maria Grazia Spillantini +15 more
TL;DR: The genetic links between these disorders are explored and the pathology of Sanfilippo syndrome is studied to investigate a common pathway toward α‐synuclein aggregation.
Journal ArticleDOI
Gene expression changes in long term expanded human neural progenitor cells passaged by chopping lead to loss of neurogenic potential in vivo.
Lucy Anderson,Rowan M Burnstein,Xiaoling He,Richard Luce,Rob Furlong,Thomas Foltynie,Peter Sykacek,David K. Menon,Maeve A. Caldwell +8 more
TL;DR: In this article, human foetal cortical tissue was cultured in the presence of either EGF, or FGF-2, or a combination of both using a unique chopping method in which cell to cell contact is maintained.
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Differences in MDS‐UPDRS Scores Based on Hoehn and Yahr Stage and Disease Duration
Matej Skorvanek,Pablo Martinez-Martin,Norbert Kovács,Mayela Rodríguez-Violante,Jean-Christophe Corvol,Pille Taba,Klaus Seppi,Oleg Levin,Anette Schrag,Thomas Foltynie,Mario Alvarez-Sanchez,Tomoko Arakaki,Zsuzsanna Aschermann,Iciar Aviles-Olmos,Eve Benchetrit,Charline Benoit,Alberto Bergareche-Yarza,Amin Cervantes-Arriaga,Anabel Chade,Florence Cormier,Veronika Datieva,David A. Gallagher,Nelida Garretto,Zuzana Gdovinova,Oscar S. Gershanik,Milan Grofik,Vladimir Han,Jing Huang,Liis Kadastik-Eerme,Monica M. Kurtis,Graziella Mangone,Juan Carlos Martínez-Castrillo,Amelia Mendoza-Rodriguez,Michal Minár,Henry Moore,Mari Muldmaa,Christoph Mueller,Bernadette Pinter,Werner Poewe,Karin Rallmann,Eva Reiter,Carmen Rodriguez-Blazquez,Carlos Singer,Barbara C. Tilley,Peter Valkovič,Christopher G. Goetz,Glenn T. Stebbins +46 more
TL;DR: In this paper, the authors analyzed MDS-UPDRS scores on Parts I through IV and their differences based on HY stage and disease duration in a large cohort of patients with Parkinson's disease.
Journal ArticleDOI
Tracking Parkinson's: study design and baseline patient data
Naveed Malek,Diane M A Swallow,Katherine A Grosset,Michael A Lawton,Sarah L Marrinan,Alexander C Lehn,Catherine Bresner,Nin Bajaj,Roger A. Barker,Yoav Ben-Shlomo,David J. Burn,Thomas Foltynie,John Hardy,Huw R. Morris,Nigel Williams,Nicholas W. Wood,Donald G. Grosset +16 more
TL;DR: The Tracking Parkinson's (TPD) study as mentioned in this paper is a multicentre prospective longitudinal epidemiologic and biomarker study of Parkinson's disease (PD), which is driven by both genetic and epidemiological influences.
Journal ArticleDOI
Localization of beta and high-frequency oscillations within the subthalamic nucleus region
B. C. M. van Wijk,B. C. M. van Wijk,A Pogosyan,Marwan Hariz,Marwan Hariz,Harith Akram,Thomas Foltynie,Patricia Limousin,Andreas Horn,Andreas Horn,Siobhan Ewert,Siobhan Ewert,Peter Brown,Peter Brown,Vladimir Litvak +14 more
TL;DR: High-frequency oscillations within the 150–400 Hz range are found to correlate with severity of motor impairment and phase-amplitude coupling, and are likely to arise from spatially close, but slightly more superior neural populations than beta oscillations.