T
Thomas Foltynie
Researcher at UCL Institute of Neurology
Publications - 381
Citations - 26959
Thomas Foltynie is an academic researcher from UCL Institute of Neurology. The author has contributed to research in topics: Deep brain stimulation & Parkinson's disease. The author has an hindex of 80, co-authored 352 publications receiving 21023 citations. Previous affiliations of Thomas Foltynie include University College London & University of Kent.
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Journal ArticleDOI
Saccadic latency distributions in Parkinson’s disease and the effects of l -dopa
Andrew W. Michell,Zheyu Xu,D. Fritz,Simon J.G. Lewis,Thomas Foltynie,Caroline H. Williams-Gray,Trevor W. Robbins,Roger H. S. Carpenter,Roger A. Barker +8 more
TL;DR: A novel effect of dopamine on saccadic latency, implying that it influences the neural decision process itself, is demonstrated, and the effects of l-dopa on neural decision making are discussed, where it is postulated to increase the criterion level of evidence required before the decision to move is made.
Journal ArticleDOI
Differentiation and migration of long term expanded human neural progenitors in a partial lesion model of Parkinson's disease.
Rowan M Burnstein,Thomas Foltynie,Xiaoling He,David K. Menon,Clive N. Svendsen,Maeve A. Caldwell +5 more
TL;DR: Human neural progenitor cells may provide a source of cells for use in the treatment of Parkinson's disease, and there was no significant behavioural recovery or effect of transplanted HNPCs on the loss of dopaminergic cells from the host brain.
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Diabetes medications and risk of Parkinson's disease: a cohort study of patients with diabetes
Ruth Brauer,Li Wei,Tian-Tian Ma,Dilan Athauda,Christine Girges,Nirosen Vijiaratnam,Grace Auld,Cate Whittlesea,Ian C. K. Wong,Ian C. K. Wong,Thomas Foltynie +10 more
TL;DR: A longitudinal study of approximately 100,000 patients with diabetes reveals a lower risk of incident Parkinson’s disease in those treated with GLP-1 mimetics or DPP-4 inhibitors compared to users of other oral antidiabetic drugs.
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Decision making, impulsivity, and addictions: Do Parkinson's disease patients jump to conclusions?
Atbin Djamshidian,Sean S. O'Sullivan,Y Sanotsky,Stephen Sharman,Yuriy Matviyenko,Thomas Foltynie,Rosanna Michalczuk,Iciar Aviles-Olmos,Ludmyla Fedoryshyn,Karen M. Doherty,Yuriy Filts,Marianna Selikhova,Henrietta Bowden-Jones,Eileen M. Joyce,Andrew J. Lees,Bruno B. Averbeck,Bruno B. Averbeck +16 more
TL;DR: PD patients who had an ICB showed similar behavior to illicit substance abusers, whereas patients without ICBs more closely resembled pathological gamblers, and there was no difference in working memory performance within the PD groups.
Journal ArticleDOI
Improving Targeting in Image-Guided Frame-Based Deep Brain Stimulation
Etienne Holl,Erika A. Petersen,Thomas Foltynie,Irene Martinez-Torres,Patricia Limousin,Marwan Hariz,Ludvic Zrinzo +6 more
TL;DR: After calibration of a systematic targeting error an MR image-guided stereotactic approach would be expected to deliver 97% of all electrodes to within 2 mm of the intended target point with a single brain pass.