U
Urban Lendahl
Researcher at Karolinska Institutet
Publications - 242
Citations - 31645
Urban Lendahl is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Notch signaling pathway & Nestin. The author has an hindex of 79, co-authored 228 publications receiving 28639 citations. Previous affiliations of Urban Lendahl include University of Hong Kong & Åbo Akademi University.
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Journal ArticleDOI
Fetal ventral mesencephalon of human and rat origin maintained in vitro and transplanted to 6-hydroxydopamine-lesioned rats gives rise to grafts rich in dopaminergic neurons
Christian Spenger,Nadia S. K. Haque,Lorenz Studer,L. Evtouchenko,Bendicht Peter Wagner,Beatrice Bühler,Urban Lendahl,Stephen B. Dunnett,Rolf W. Seiler +8 more
TL;DR: The results promote the feasibility of in vitro maintenance of fetal human and rat nigral tissue prior to transplantation using the free-floating roller tube technique.
Journal ArticleDOI
Cholangiopathies - Towards a molecular understanding.
TL;DR: The current understanding of the causes of cholangiopathies, which can be genetic, viral or environmental, and the few treatment options that are currently available beyond liver transplantation are described.
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Biliary Atresia – emerging diagnostic and therapy opportunities
Urban Lendahl,Urban Lendahl,Vincent C.H. Lui,Vincent C.H. Lui,Patrick Ho Yu Chung,Patrick Ho Yu Chung,Paul K.H. Tam,Paul K.H. Tam +7 more
TL;DR: A review of recent progress in the understanding of liver development with a focus on cholangiocyte differentiation and how use of technical platforms, including rodent, zebrafish and organoid models, advances our understanding of Biliary Atresia is presented in this article.
Journal ArticleDOI
The Balbiani ring 2 gene in Chironomus tentans is built from two types of tandemly arranged major repeat units with a common evolutionary origin.
Lars Wieslander,Urban Lendahl +1 more
TL;DR: The two major repeat units of the Balbiani ring 2 gene show a high degree of sequence homology, indicating that the pCt 7 and pCt 63 sequence blocks within the Br 2 gene have evolved through stepwise amplification from a common ancestral sequence.
Journal ArticleDOI
A 1.8kb GFAP-promoter fragment is active in specific regions of the embryonic CNS.
Johanna Andrae,Erik Bongcam-Rudloff,Inga Hansson,Urban Lendahl,Bengt Westermark,Monica Nistér +5 more
TL;DR: The results indicate that GFAP activity is regulated in a region-specific manner during central nervous system (CNS) development and that the gene is turned on in different cell types independently.