V
Vojo Deretic
Researcher at University of New Mexico
Publications - 278
Citations - 51981
Vojo Deretic is an academic researcher from University of New Mexico. The author has contributed to research in topics: Autophagy & Phagosome. The author has an hindex of 101, co-authored 269 publications receiving 45639 citations. Previous affiliations of Vojo Deretic include University of Texas at Austin & University of Michigan.
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Journal ArticleDOI
Control of AlgU, a member of the sigma E-like family of stress sigma factors, by the negative regulators MucA and MucB and Pseudomonas aeruginosa conversion to mucoidy in cystic fibrosis.
TL;DR: The biochemical basis of conversion to mucoidy in P. aeruginosa is analyzed to support a model in which a multicomponent system, encompassing an anti-delta factor and elements in the periplasmic compartment, modulates activity of AlgU.
Journal ArticleDOI
A comprehensive glossary of autophagy-related molecules and processes.
Daniel J. Klionsky,Patrice Codogno,Ana Maria Cuervo,Vojo Deretic,Zvulun Elazar,Juan Fueyo-Margareto,David A. Gewirtz,Guido Kroemer,Beth Levine,Noboru Mizushima,David C. Rubinsztein,Michael Thumm,Sharon A. Tooze +12 more
TL;DR: A comprehensive glossary of autophagy-related terms is developed to provide a quick reference for researchers who need a brief reminder of the regulatory effects of transcription factors or chemical agents that induce or inhibit Autophagy.
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Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria
Sudha Singh,Wojciech Ornatowski,Isabelle Vergne,John Naylor,Mónica A. Delgado,Esteban A. Roberts,Marisa Ponpuak,Marisa Ponpuak,Sharon Master,Manohar Pilli,Eileen White,Masaaki Komatsu,Masaaki Komatsu,Vojo Deretic +13 more
TL;DR: By acting on mitochondria, IRGM confers autophagic protection or cell death, explaining IRGM action both in defence against tuberculosis and in the damaging inflammation caused by Crohn's disease.
Journal ArticleDOI
Mycobacterium tuberculosis signal transduction system required for persistent infections.
Thomas C. Zahrt,Vojo Deretic +1 more
TL;DR: Results indicate that two-component systems are important for adaptation of the tubercle bacillus during stages of persistent infection.
Journal ArticleDOI
Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy.
Tomonori Kimura,Jingyue Jia,Suresh Kumar,Seong Won Choi,Yuexi Gu,Michal H. Mudd,Nicolas Dupont,Shanya Jiang,Ryan Peters,Farzin Farzam,Ashish Jain,Keith A. Lidke,Christopher M. Adams,Terje Johansen,Vojo Deretic +14 more
TL;DR: It is shown that in response to lysosomal damage, the prototypical cytosolic secretory autophagy cargo IL‐1β is recognized by specialized secretoryautosolic cargo receptor TRIM16 and that this receptor interacts with the R‐SNARE Sec22b to recruit cargo to the LC3‐II+ sequestration membranes.