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Christopher M. Adams

Researcher at Roy J. and Lucille A. Carver College of Medicine

Publications -  131
Citations -  14482

Christopher M. Adams is an academic researcher from Roy J. and Lucille A. Carver College of Medicine. The author has contributed to research in topics: Skeletal muscle & Muscle atrophy. The author has an hindex of 47, co-authored 126 publications receiving 12123 citations. Previous affiliations of Christopher M. Adams include University of Iowa & Mayo Clinic.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Genetic mechanisms of critical illness in Covid-19.

Erola Pairo-Castineira, +1449 more
- 04 Mar 2021 - 
TL;DR: The GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2244 critically ill Covid-19 patients from 208 UK intensive care units is reported, finding evidence in support of a causal link from low expression of IFNAR2, and high expression of TYK2, to life-threatening disease.
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Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na^+ channel

Peter M. Snyder, +7 more
- 15 Dec 1995 - 
TL;DR: By deleting a conserved motif, Liddle's mutations increase the number of Na+ channels in the apical membrane, which increases renal Na+ absorption and creates a predisposition to hypertension.
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Cholesterol and 25-Hydroxycholesterol Inhibit Activation of SREBPs by Different Mechanisms, Both Involving SCAP and Insigs

Christopher M. Adams, +6 more
- 10 Dec 2004 - 
TL;DR: It is demonstrated that cholesterol and its hydroxylated derivative, 25-hydroxycholesterol (25-HC), inhibit cholesterol synthesis by two different mechanisms, both involving the proteins that control sterol regulatory element-binding proteins (SREBPs), membrane-bound transcription factors that activate genes encoding enzymes of lipid synthesis.
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Prospective Randomized Controlled Trial of an Intramedullary Nail Versus Dynamic Screw and Plate for Intertrochanteric Fractures of the Femur

Christopher M. Adams, +3 more
- 01 Aug 2001 - 
TL;DR: The use of an intramedullary device in the treatment of intertrochanteric femoral fractures is still associated with a higher but nonsignificant risk of postoperative complications and routine use of the Gamma nail in this type of fracture cannot be recommended over the current standard treatment of dynamic hip screw and plate.