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Daniel J. Klionsky

Researcher at University of Michigan

Publications -  627
Citations -  106958

Daniel J. Klionsky is an academic researcher from University of Michigan. The author has contributed to research in topics: Autophagy & Vacuole. The author has an hindex of 131, co-authored 565 publications receiving 90977 citations. Previous affiliations of Daniel J. Klionsky include National Institute for Basic Biology, Japan & Royal Veterinary College.

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Journal ArticleDOI

Autophagy fights disease through cellular self-digestion

TL;DR: Understanding autophagy may ultimately allow scientists and clinicians to harness this process for the purpose of improving human health, and to play a role in cell death.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Development by Self-Digestion: Molecular Mechanisms and Biological Functions of Autophagy

TL;DR: This review summarizes the current knowledge about the molecular machinery of autophagy and the role of the autophagic machinery in eukaryotic development and identifies a set of evolutionarily conserved genes that are essential forAutophagy.
Journal ArticleDOI

Autophagy as a Regulated Pathway of Cellular Degradation

TL;DR: The core protein machinery that is necessary to drive formation and consumption of intermediates in the macroautophagy pathway includes a ubiquitin-like protein conjugation system and a protein complex that directs membrane docking and fusion at the lysosome or vacuole.