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Wenjun Song
Researcher at University of Hong Kong
Publications - 38
Citations - 2717
Wenjun Song is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 19, co-authored 31 publications receiving 2331 citations. Previous affiliations of Wenjun Song include Guangzhou Medical University & Li Ka Shing Faculty of Medicine, University of Hong Kong.
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Journal ArticleDOI
Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome
Yu Chen,Weifeng Liang,Shigui Yang,Nanping Wu,Hainv Gao,Jifang Sheng,Hangping Yao,Jianer Wo,Qiang Fang,Dawei Cui,Yongcheng Li,Xing Yao,Yun-Tao Zhang,Haibo Wu,Shufa Zheng,Hongyan Diao,Shichang Xia,Yanjun Zhang,Kwok-Hung Chan,Hoi-Wah Tsoi,Jade Lee-Lee Teng,Wenjun Song,Pui Wang,Siu-Ying Lau,Min Zheng,Jasper Fuk-Woo Chan,Kelvin K. W. To,Honglin Chen,Lanjuan Li,Kwok-Yung Yuen +29 more
TL;DR: Cross species poultry-to-person transmission of this new reassortant H7N9 virus is associated with severe pneumonia and multiorgan dysfunction in human beings and monitoring of the viral evolution and further study of disease pathogenesis will improve disease management, epidemic control, and pandemic preparedness.
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Prevalence and Genetic Diversity of Coronaviruses in Bats from China
Xianchun Tang,Jinxia Zhang,Shuyi Zhang,Peigang Wang,Xiaohui Fan,Lifeng Li,Gang Li,Bai Qing Dong,William J. Liu,C. L. Cheung,K. M. Xu,Wenjun Song,Dhanasekaran Vijaykrishna,Leo L.M. Poon,Joseph S. M. Peiris,Gavin J. D. Smith,Honglin Chen,Yi Guan +17 more
TL;DR: The findings of this study suggest that bats may play an integral role in the ecology and evolution of coronavirus ecology, in particular the role of bats and other wild animals.
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Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction.
Siu Ying Lau,Pui Wang,Bobo Wing-Yee Mok,Anna Jinxia Zhang,Hin Chu,Andrew Chak-Yiu Lee,Shaofeng Deng,Pin Chen,Kwok-Hung Chan,Wenjun Song,Zhiwei Chen,Kelvin K. W. To,Jasper Fuk-Woo Chan,Kwok-Yung Yuen,Honglin Chen +14 more
TL;DR: Infection of hamsters shows that one of the variants which carries deletion of 10 amino acids does not cause the body weight loss or more severe pathological changes in the lungs that is associated with wild type virus infection, and it is suggested that the unique cleavage motif promoting SARS-CoV-2 infection in humans may be under strong selective pressure.
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Differentiated human airway organoids to assess infectivity of emerging influenza virus
Jie Zhou,Cun Li,Norman Sachs,Man Chun Chiu,Bosco Ho-Yin Wong,Hin Chu,Vincent Kwok-Man Poon,Dong Wang,Xiaoyu Zhao,Lei Wen,Wenjun Song,Wenjun Song,Shuofeng Yuan,Kenneth K. Y. Wong,Jasper Fuk-Woo Chan,Kelvin K. W. To,Honglin Chen,Hans Clevers,Kwok-Yung Yuen +18 more
TL;DR: The proximal differentiated airway organoids can be utilized to predict the infectivity of influenza viruses and, more broadly, provide a universal platform for studying the biology and pathology of the human airway.
Journal ArticleDOI
Human Infection with Highly Pathogenic Avian Influenza A(H7N9) Virus, China.
Changwen Ke,Chris Ka Pun Mok,Wenfei Zhu,Haibo Zhou,Jianfeng He,Wenda Guan,Jie Wu,Wenjun Song,Dayan Wang,Jiexiong Liu,Qinhan Lin,Daniel Ka Wing Chu,Lei Yang,Nanshan Zhong,Zifeng Yang,Yuelong Shu,Joseph S. M. Peiris +16 more
TL;DR: The fatal case of a patient in China who was infected with an A(H7N9) virus having a polybasic amino acid sequence at its hemagglutinin cleavage site (PEVPKRKRTAR/GL), a sequence suggestive of high pathogenicity in birds, is reported.