W
Winfried März
Researcher at Heidelberg University
Publications - 398
Citations - 46505
Winfried März is an academic researcher from Heidelberg University. The author has contributed to research in topics: Vitamin D and neurology & Genome-wide association study. The author has an hindex of 74, co-authored 361 publications receiving 36423 citations. Previous affiliations of Winfried März include University of Ulm & University of Graz.
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Journal ArticleDOI
Quantification of HDL Proteins, Cardiac Events, and Mortality in Patients with Type 2 Diabetes on Hemodialysis
Chantal Kopecky,Bernd Genser,Bernd Genser,Christiane Drechsler,Vera Krane,Christopher C. Kaltenecker,Markus Hengstschläger,Winfried März,Winfried März,Winfried März,Christoph Wanner,Marcus D. Säemann,Thomas Weichhart +12 more
TL;DR: Findings indicate that a remodeling of the HDL proteome was associated with a higher risk for cardiovascular events and mortality in patients with ESRD.
Journal ArticleDOI
Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality
Stefan J Schunk,Marcus E. Kleber,Marcus E. Kleber,Winfried März,Winfried März,Winfried März,Shichao Pang,Stephen Zewinger,Sarah Triem,Philipp Ege,Matthias C. Reichert,Marcin Krawczyk,Marcin Krawczyk,Susanne N. Weber,Isabella Jaumann,David Schmit,Tamim Sarakpi,Stefan Wagenpfeil,Rafael Kramann,Eric Boerwinkle,Eric Boerwinkle,Christie M. Ballantyne,Megan L. Grove,Vinicius Tragante,Anna P. Pilbrow,A. Mark Richards,Vicky A. Cameron,Robert N. Doughty,Marie-Pierre Dubé,Jean-Claude Tardif,Yassamin Feroz-Zada,Maxine Sun,Chang Liu,Yi-An Ko,Arshed A. Quyyumi,Jaana Hartiala,W.H. Wilson Tang,W.H. Wilson Tang,Stanley L. Hazen,Stanley L. Hazen,Hooman Allayee,Caitrin W. McDonough,Yan Gong,Rhonda M. Cooper-DeHoff,Julie A. Johnson,Markus Scholz,Andrej Teren,Ralph Burkhardt,Ralph Burkhardt,Andreas Martinsson,J. Gustav Smith,Lars Wallentin,Lars Wallentin,Stefan James,Stefan James,Niclas Eriksson,Niclas Eriksson,Harvey D. White,Claes Held,Claes Held,Dawn M. Waterworth,Stella Trompet,J. Wouter Jukema,Ian Ford,David J. Stott,Naveed Sattar,Sharon Cresci,John A. Spertus,Hannah Campbell,Sascha Tierling,Jörn Walter,Emmanuel Ampofo,Barbara A. Niemeyer,Peter Lipp,Heribert Schunkert,Michael Böhm,Wolfgang Koenig,Wolfgang Koenig,Danilo Fliser,Ulrich Laufs,Thimoteus Speer +80 more
TL;DR: This study provides evidence for a substantial role of genetically driven systemic inflammation in CVD and highlights the NLRP3 inflammasome as a therapeutic target.
Journal ArticleDOI
Vitamin D deficiency parallels inflammation and immune activation, the Ludwigshafen Risk and Cardiovascular Health (LURIC) study
Christian Murr,Stefan Pilz,Tanja B. Grammer,Marcus E. Kleber,Andreas Meinitzer,Bernhard O. Boehm,Winfried März,Dietmar Fuchs +7 more
TL;DR: The results indicate increased inflammatory processes in patients with low vitamin D status and further studies should clarify the underlying mechanisms for the observed associations of vitamin Dstatus and inflammatory parameters.
Journal ArticleDOI
Lipopolysaccharide-binding protein (LBP) is associated with total and cardiovascular mortality in individuals with or without stable coronary artery disease – Results from the Ludwigshafen Risk and Cardiovascular Health Study (LURIC)
Philipp M. Lepper,Marcus E. Kleber,Tanja B. Grammer,K Hoffmann,Simone Dietz,Bernhard R. Winkelmann,Bernhard O. Boehm,Winfried März,Winfried März +8 more
TL;DR: Serum LBP concentration was significantly increased in 2298 patients with angiographically confirmed CAD and LBP was a significant and independent predictor of total and cardiovascular mortality, which underscores the potential importance of innate immune mechanisms for atherosclerosis.
Journal ArticleDOI
Routinely available biomarkers improve prediction of long-term mortality in stable coronary artery disease: the Vienna and Ludwigshafen Coronary Artery Disease (VILCAD) risk score
Georg Goliasch,Marcus E. Kleber,Bernhard Richter,Max Plischke,Matthias Hoke,Arvand Haschemi,Rodrig Marculescu,Georg Endler,Tanja B. Grammer,Stefan Pilz,Andreas Tomaschitz,Günther Silbernagel,Gerald Maurer,Oswald Wagner,Kurt Huber,Winfried März,Winfried März,Winfried März,Christine Mannhalter,Alexander Niessner +19 more
TL;DR: The VILCAD score based on a routinely available set of risk factors, measures of cardiac function, and comorbidities outperforms established risk prediction algorithms and might improve the identification of high-risk patients for a more intensive treatment.